Pharmacology- Pharmacokinetics (Exam 1) Questions With Correct Answers.

Pharmacology- Pharmacokinetics (Exam 1)
Questions With Correct Answers

What is Pharmacokinetics? - CORRECT ANSWER✔✔-What the body does to the
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drug


What are the processes of pharmacokinetics? - CORRECT ANSWER✔✔-
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Absorption
Distribution
Metabolism (bio-transformation) |




Excretion


EXCEPT ORAL: Absorption, HEPATIC FIRST PASS, distribution, metabolism,
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excretion


What types of drug molecules move across membranes more easily? - CORRECT
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ANSWER✔✔-small
non ionized
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lipid soluable
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What drugs are absorbed faster? Why is this? - CORRECT ANSWER✔✔-IV, IM, SQ;
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Because it is already i solution and has no barrier it goes directly into the blood
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stream

, What other factors impact absorption? - CORRECT ANSWER✔✔-Route of the
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drug (IV, IM, SQ faster)
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Drug formulation (water soluble needs carrier; lipid soluble is faster)
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Circulatory status (Impaired/Immature slower)
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Acidity of stomach (lower pH takes longer to absorb)
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Food


Integrity of mucous membranes
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What is the blood brain barrier and how does it impact distribution? - CORRECT
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ANSWER✔✔-Super tight packed capillaries, protective mechanism very hard for| | | | | | | | |


any drugs to get in or out
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Does the placenta work the same way as the blood brain barrier? - CORRECT
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ANSWER✔✔-No, the placenta is an open system which easily lets drugs get in
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What protein should the RN be monitoring and how does protein impact
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distribution? - CORRECT ANSWER✔✔-Albumin 3.5-5 g/dL
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