The lectin Dolichus biflorus agglutinates which types of cells - ANSWER A1B
Transfusion-related acute lung injury (TRALI) is a serious blood transfusion complication that
can be characterized by all of the following except - ANSWER increased central venous
pressure
What would be considered a common characteristic of anti-Jka and anti-Jkb - ANSWER
the antibodies show dosage with Kidd antigens on red cells
ABO antibodies are classified as which of the following two immunoglobulin classes - AN-
SWER IgG and IgM
Which of the following is true regarding the Lutheran blood group system - ANSWER Lub
is a high frequency antigen
A Bombay individual's blood specimen can be differentiated from a blood specimen of a
group O person by which of the following - ANSWER testing with anti-H lectin (Ulex eru-
opaeus)
If Jka is showing dosage, how might reactions on an antibody panel appear - ANSWER
Weaker if heterozygous for Jka and Jkb
Why is it dangerous to transfuse a blood group O person with a unit of blood group A - AN-
SWER The patient's anti-A would destroy the donor's cells with severe consequences to
the patient
1
,A woman with the blood type AB will show antigens for both the A and B blood groups. This
is an example of what type of inheritance - ANSWER codominance
A primary immune response typically presents with which class of antibody - ANSWER
IgM
Which of the following blood components contains the most factor VIII concentration rela-
tive to the unit volume - ANSWER cyoprecipitated AHF
What is the minimum volume (milliliters) of Rh positive red blood cells that would be
needed to produce anti-D in an Rh negative individual - ANSWER < 0.1 mL
If an individual has blood type O, which of the following are possible genotypes - AN-
SWER OO only
When a unit of packed RBC's split using the open system, each portion of the unit must be
issued - ANSWER within 24 hours
An exchange transfusion has been ordered for a low birth weight infant. The physician has
ordered irradiated Red Blood Cells for this purpose. Why is it necessary to irradiate the
blood products for this patient - ANSWER to prevent transfusion-associated graft-versus-
host disease (TA-GVHD)
When a unit of packed RBC's is split using the open system, each portion of the unit must be
issued - ANSWER within 24 hrs
Which of the following ABO blood groups has the highest number of H antigen sites on the
RBC membrane - ANSWER Group O cells
What is the minimum acceptable hematocrit level for a male that wants to donate double
RBC units through RBC apheresis - ANSWER 40%
2
,Donor and recipient blood samples must be kept for at least how long after transfusion - AN-
SWER 7 days
Which of the following patients are at risk for transfusion-associated graft versus host dis-
ease (TA-GVHD) and require irradiated cellular blood products - ANSWER immunocom-
promised patients including neonates less than 4 months of age and patients receiving
chemotherapy
What is considered the definition of allogeneic blood - ANSWER donated by a donor for a
recipient other than the donor to use
Compared to plasma frozen within 8 hours of collection, plasma frozen within 24 hours of
collection will likely have reduced levels of Factor - ANSWER VIII
The immediate spin phase of an indirect antiglobulin test (antibody screen and antibody
identification) could most likely lead to the detection of which of the following - ANSWER
clinically insignificant cold antibodies
Leukocyte-reduced blood products may be administered to reduce the risk of febrile reac-
tions and what disease or condition - ANSWER cytomegalovirus
Which is in the correct order from the lowest concentration of H antigen to the highest con-
centration of H antigen - ANSWER Bombay, A1B, A2, A2B, B, A1, O
Compared to the primary immune response, the secondary immune response typically
demonstrates - ANSWER more antibodies produced
Which Lewis antigen(s) would be detected when phenotyping the red cells of an adult who
has the Le, Se, and H genes - ANSWER Leb
3
, What are the possible ABO genotypes of offspring from parents whose genotypes are OO
and AB - ANSWER OA and OB
Which blood group is considered the "universal" donor when transfusing Red Blood Cells -
ANSWER Group O
What is the minimum hemoglobin concentration required for autologous blood donation -
ANSWER 11 g/dL
Which of the following noninfectious complications of blood transfusion is prevented by the
irradiation of blood components - ANSWER transfusion-associated graft versus host dis-
ease (TA-GVHD)
Donor red blood cells (RBCs) were collected on July 12th of this year. The RBCs where then
frozen in glycerol on July 17th (5days later) and stored at -65C.
What should the expiration date read on the frozen RBC unit - ANSWER July 12th: 10
years from collection date
Which of the following packed RBCs could be transfused to a group O patient - ANSWER
Group O
Which of the following group B antigens is generally associated with a mixed field reaction -
ANSWER B3
Persons who have received a dura mater transplant are not eligible to donate blood and are
permanently deferred. This is due to an increased risk of which of the following - AN-
SWER CJD or vCJD
what is the most common treatment for hemolytic disease of the fetus and newborn (HDFN)
due to ABO incompatibility - ANSWER phototherapy
4
Transfusion-related acute lung injury (TRALI) is a serious blood transfusion complication that
can be characterized by all of the following except - ANSWER increased central venous
pressure
What would be considered a common characteristic of anti-Jka and anti-Jkb - ANSWER
the antibodies show dosage with Kidd antigens on red cells
ABO antibodies are classified as which of the following two immunoglobulin classes - AN-
SWER IgG and IgM
Which of the following is true regarding the Lutheran blood group system - ANSWER Lub
is a high frequency antigen
A Bombay individual's blood specimen can be differentiated from a blood specimen of a
group O person by which of the following - ANSWER testing with anti-H lectin (Ulex eru-
opaeus)
If Jka is showing dosage, how might reactions on an antibody panel appear - ANSWER
Weaker if heterozygous for Jka and Jkb
Why is it dangerous to transfuse a blood group O person with a unit of blood group A - AN-
SWER The patient's anti-A would destroy the donor's cells with severe consequences to
the patient
1
,A woman with the blood type AB will show antigens for both the A and B blood groups. This
is an example of what type of inheritance - ANSWER codominance
A primary immune response typically presents with which class of antibody - ANSWER
IgM
Which of the following blood components contains the most factor VIII concentration rela-
tive to the unit volume - ANSWER cyoprecipitated AHF
What is the minimum volume (milliliters) of Rh positive red blood cells that would be
needed to produce anti-D in an Rh negative individual - ANSWER < 0.1 mL
If an individual has blood type O, which of the following are possible genotypes - AN-
SWER OO only
When a unit of packed RBC's split using the open system, each portion of the unit must be
issued - ANSWER within 24 hours
An exchange transfusion has been ordered for a low birth weight infant. The physician has
ordered irradiated Red Blood Cells for this purpose. Why is it necessary to irradiate the
blood products for this patient - ANSWER to prevent transfusion-associated graft-versus-
host disease (TA-GVHD)
When a unit of packed RBC's is split using the open system, each portion of the unit must be
issued - ANSWER within 24 hrs
Which of the following ABO blood groups has the highest number of H antigen sites on the
RBC membrane - ANSWER Group O cells
What is the minimum acceptable hematocrit level for a male that wants to donate double
RBC units through RBC apheresis - ANSWER 40%
2
,Donor and recipient blood samples must be kept for at least how long after transfusion - AN-
SWER 7 days
Which of the following patients are at risk for transfusion-associated graft versus host dis-
ease (TA-GVHD) and require irradiated cellular blood products - ANSWER immunocom-
promised patients including neonates less than 4 months of age and patients receiving
chemotherapy
What is considered the definition of allogeneic blood - ANSWER donated by a donor for a
recipient other than the donor to use
Compared to plasma frozen within 8 hours of collection, plasma frozen within 24 hours of
collection will likely have reduced levels of Factor - ANSWER VIII
The immediate spin phase of an indirect antiglobulin test (antibody screen and antibody
identification) could most likely lead to the detection of which of the following - ANSWER
clinically insignificant cold antibodies
Leukocyte-reduced blood products may be administered to reduce the risk of febrile reac-
tions and what disease or condition - ANSWER cytomegalovirus
Which is in the correct order from the lowest concentration of H antigen to the highest con-
centration of H antigen - ANSWER Bombay, A1B, A2, A2B, B, A1, O
Compared to the primary immune response, the secondary immune response typically
demonstrates - ANSWER more antibodies produced
Which Lewis antigen(s) would be detected when phenotyping the red cells of an adult who
has the Le, Se, and H genes - ANSWER Leb
3
, What are the possible ABO genotypes of offspring from parents whose genotypes are OO
and AB - ANSWER OA and OB
Which blood group is considered the "universal" donor when transfusing Red Blood Cells -
ANSWER Group O
What is the minimum hemoglobin concentration required for autologous blood donation -
ANSWER 11 g/dL
Which of the following noninfectious complications of blood transfusion is prevented by the
irradiation of blood components - ANSWER transfusion-associated graft versus host dis-
ease (TA-GVHD)
Donor red blood cells (RBCs) were collected on July 12th of this year. The RBCs where then
frozen in glycerol on July 17th (5days later) and stored at -65C.
What should the expiration date read on the frozen RBC unit - ANSWER July 12th: 10
years from collection date
Which of the following packed RBCs could be transfused to a group O patient - ANSWER
Group O
Which of the following group B antigens is generally associated with a mixed field reaction -
ANSWER B3
Persons who have received a dura mater transplant are not eligible to donate blood and are
permanently deferred. This is due to an increased risk of which of the following - AN-
SWER CJD or vCJD
what is the most common treatment for hemolytic disease of the fetus and newborn (HDFN)
due to ABO incompatibility - ANSWER phototherapy
4
