and Midterm and final Questions
And Answers Latest Update 2026
package
Pharmacokinetics - CORRECT ANSWERSThe study of drug absorption, distribution,
metabolism, and excretion in the body
"What the body does to the drug"
, Factors that affect drug absorption (5) - CORRECT ANSWERSRate of dissolution
Surface area
Blood flow
Lipid solubility
PH partitioning
Factors that affect drug distribution (4) - CORRECT ANSWERSBlood flow to tissues
Ability to exit vascular system
Blood-brain barrier
Protein-binding capacity
Adverse reactions: drug reaction - CORRECT ANSWERSMost complex, difficult to
determine
Teratogenic effects - CORRECT ANSWERSCauses birth defects
Mutagenic effects - CORRECT ANSWERSAble to cause changes in genetic tissue
Carcinogen - CORRECT ANSWERSSubstances that can cause cancer
Toxicology - CORRECT ANSWERSThe study of adverse effects of chemicals and their
compounds on living organisms and tissues
Xenobiotics - CORRECT ANSWERSSubstances that are foreign to the body
Synthetic chemical compounds
Medications
All can potentially adversely affect the body
*Occasionally can be transformed into toxic metabolite
Cytochrome P450 (CYP450) - CORRECT ANSWERSXenobioitic-metabolizing enzymes
Necessary for the production of cholesterol and steroids
Role of CYP450 - CORRECT ANSWERSDetoxification of chemicals
Drug metabolism
CYP450: cyto - CORRECT ANSWERSBinds to cell membrane
CYP450: chrome + p - CORRECT ANSWERSContains heme pigment
CYP450: 450 mm - CORRECT ANSWERSAbsorbs light at 450 mm wavelength when
exposed to carbon monoxide (CO)