NR-566: ADVANCED PHARMACOLOGY
CARE OF THE FAMILY COMPLETE
STUDY & EXAM BUNDLE (250+
QUESTIONS)
Level: Family Nurse Practitioner (FNP) Graduate
========================================
========================================
TABLE OF CONTENTS
1. Study Guide – Drug Classifications by Body System
• Cardiovascular Pharmacology
• Respiratory Pharmacology
• Endocrine & Diabetes Pharmacology
• Infectious Disease & Antimicrobials
• CNS & Psychiatric Pharmacology
• Pain Management & Opioids
• GI Pharmacology
• Special Populations (Peds, Pregnancy, Geriatrics, Lactation)
• Drug Interactions & Adverse Effects
2. Review Sheets – High-Yield Tables & Mnemonics
3. Practice Exam with Rationales (250+ Questions)
• Part A: Multiple Choice (150 questions)
,
• Part B: Multiple Answer / SATA (100 questions)
• Rationales immediately follow each question
======================================== SECTION 1:
STUDY GUIDE
1.1 Cardiovascular Pharmacology
ANTIHYPERTENSIVES – FIRST-LINE BY CONDITION
Drug Class Examples Indication Key Counseling
& Monitoring
ACE inhibitors Lisinopril, HTN, HF, CKD, Dry cough (5-
(ACEi) enalapril, diabetes, post-MI 20%),
captopril, angioedema (rare
ramipril but serious),
hyperkalemia,
↑Cr (20-30%
acceptable).
Teratogenic –
avoid pregnancy.
Monitor K+, Cr,
BP.
ARBs Losartan, HTN, HF, CKD No cough, still
valsartan, (ACEi teratogenic, risk
candesartan, alternative if of hyperkalemia
irbesartan, cough) and ↑Cr. Less
olmesartan angioedema.
DHP CCBs Amlodipine, HTN, angina, Peripheral edema
nifedipine ER, African (dose-
felodipine Americans, dependent),
isolated systolic gingival
HTN in elderly hyperplasia,
flushing,
headache. No
,
Drug Class Examples Indication Key Counseling
& Monitoring
negative inotrope
effect.
Non-DHP CCBs Diltiazem, Rate control in Constipation
verapamil AF, angina, HTN (verapamil),
heart block,
negative inotrope
– avoid in
HFrEF. Monitor
HR, BP.
Thiazide HCTZ, HTN, edema Hypokalemia,
diuretics chlorthalidone, hyperglycemia,
indapamide hyperuricemia,
hyponatremia,
hyperlipidemia.
Chlorthalidone
preferred for CV
outcome data.
Loop diuretics Furosemide, HF (volume Hypokalemia,
torsemide, overload), hypomagnesemia
bumetanide edema, HTN , ototoxicity
with CKD (rapid IV),
metabolic
alkalosis.
Torsemide has
better
bioavailability.
Beta-blockers Metoprolol HTN, HF, Bradycardia,
(cardioselective) succinate, angina, post-MI, fatigue, masks
bisoprolol, AF (rate control) hypoglycemia,
atenolol dyslipidemia,
sexual
dysfunction. Safe
,
Drug Class Examples Indication Key Counseling
& Monitoring
in COPD/asthma
(cardioselective).
Beta-blockers Carvedilol, HTN, HF May cause
(non-selective) labetalol, (carvedilol), bronchospasm –
propranolol, migraine, tremor, avoid in asthma.
nadolol performance Labetalol used in
anxiety pregnancy.
Carvedilol has
alpha-blocking
effect →
vasodilation.
Alpha-1 blockers Doxazosin, BPH First-dose
terazosin, (tamsulosin), orthostatic
tamsulosin, HTN (not first- hypotension
alfuzosin line) (give at
bedtime),
retrograde
ejaculation, nasal
congestion.
Tamsulosin is
BPH-specific
(less
hypotension).
Central alpha Clonidine, HTN (2nd/3rd Rebound HTN
agonists methyldopa, line), pregnancy (do NOT stop
guanfacine (methyldopa), abruptly),
ADHD sedation, dry
(guanfacine) mouth.
Methyldopa is
safe in
pregnancy.
Direct Hydralazine, HTN (3rd/4th Hydralazine:
CARE OF THE FAMILY COMPLETE
STUDY & EXAM BUNDLE (250+
QUESTIONS)
Level: Family Nurse Practitioner (FNP) Graduate
========================================
========================================
TABLE OF CONTENTS
1. Study Guide – Drug Classifications by Body System
• Cardiovascular Pharmacology
• Respiratory Pharmacology
• Endocrine & Diabetes Pharmacology
• Infectious Disease & Antimicrobials
• CNS & Psychiatric Pharmacology
• Pain Management & Opioids
• GI Pharmacology
• Special Populations (Peds, Pregnancy, Geriatrics, Lactation)
• Drug Interactions & Adverse Effects
2. Review Sheets – High-Yield Tables & Mnemonics
3. Practice Exam with Rationales (250+ Questions)
• Part A: Multiple Choice (150 questions)
,
• Part B: Multiple Answer / SATA (100 questions)
• Rationales immediately follow each question
======================================== SECTION 1:
STUDY GUIDE
1.1 Cardiovascular Pharmacology
ANTIHYPERTENSIVES – FIRST-LINE BY CONDITION
Drug Class Examples Indication Key Counseling
& Monitoring
ACE inhibitors Lisinopril, HTN, HF, CKD, Dry cough (5-
(ACEi) enalapril, diabetes, post-MI 20%),
captopril, angioedema (rare
ramipril but serious),
hyperkalemia,
↑Cr (20-30%
acceptable).
Teratogenic –
avoid pregnancy.
Monitor K+, Cr,
BP.
ARBs Losartan, HTN, HF, CKD No cough, still
valsartan, (ACEi teratogenic, risk
candesartan, alternative if of hyperkalemia
irbesartan, cough) and ↑Cr. Less
olmesartan angioedema.
DHP CCBs Amlodipine, HTN, angina, Peripheral edema
nifedipine ER, African (dose-
felodipine Americans, dependent),
isolated systolic gingival
HTN in elderly hyperplasia,
flushing,
headache. No
,
Drug Class Examples Indication Key Counseling
& Monitoring
negative inotrope
effect.
Non-DHP CCBs Diltiazem, Rate control in Constipation
verapamil AF, angina, HTN (verapamil),
heart block,
negative inotrope
– avoid in
HFrEF. Monitor
HR, BP.
Thiazide HCTZ, HTN, edema Hypokalemia,
diuretics chlorthalidone, hyperglycemia,
indapamide hyperuricemia,
hyponatremia,
hyperlipidemia.
Chlorthalidone
preferred for CV
outcome data.
Loop diuretics Furosemide, HF (volume Hypokalemia,
torsemide, overload), hypomagnesemia
bumetanide edema, HTN , ototoxicity
with CKD (rapid IV),
metabolic
alkalosis.
Torsemide has
better
bioavailability.
Beta-blockers Metoprolol HTN, HF, Bradycardia,
(cardioselective) succinate, angina, post-MI, fatigue, masks
bisoprolol, AF (rate control) hypoglycemia,
atenolol dyslipidemia,
sexual
dysfunction. Safe
,
Drug Class Examples Indication Key Counseling
& Monitoring
in COPD/asthma
(cardioselective).
Beta-blockers Carvedilol, HTN, HF May cause
(non-selective) labetalol, (carvedilol), bronchospasm –
propranolol, migraine, tremor, avoid in asthma.
nadolol performance Labetalol used in
anxiety pregnancy.
Carvedilol has
alpha-blocking
effect →
vasodilation.
Alpha-1 blockers Doxazosin, BPH First-dose
terazosin, (tamsulosin), orthostatic
tamsulosin, HTN (not first- hypotension
alfuzosin line) (give at
bedtime),
retrograde
ejaculation, nasal
congestion.
Tamsulosin is
BPH-specific
(less
hypotension).
Central alpha Clonidine, HTN (2nd/3rd Rebound HTN
agonists methyldopa, line), pregnancy (do NOT stop
guanfacine (methyldopa), abruptly),
ADHD sedation, dry
(guanfacine) mouth.
Methyldopa is
safe in
pregnancy.
Direct Hydralazine, HTN (3rd/4th Hydralazine:
