tion, predictability, ease of administration, freedom of drug interactions, low cost, chemical
stability, simple generic name
Properties of medicines to consider when prescribing to patients - ANSWER 1. Absorp-
tion 2. Distribution 3. Metabolism 4. Excretion 5. Half-life 6. 1st pass effect 7. Bioavailability
8. Onset 9. Peak 10. Duration
Patient specific variabilities affecting response to medications - ANSWER 1. Bodyweight
and composition 2. Age 3. Diseasess 4. Tolerance
Pharmacodynamics - ANSWER Biochemical changes in the body from a drug.
Routes of medication administration - ANSWER PO, SC, IM, IV, TOPICAL
Therapeutic threshold - ANSWER the amount of drug needed to create a therapeutic ef-
fect and the amount of drug needed to reach toxicity.
Adverse Reaction - ANSWER Unintended and harmful reaction from the medication given
and can be life threatening.
Side effects - ANSWER Unavoidable secondary drug effect produced at therapeutic doses
example: nausea, vomiting
Allegic reactions - ANSWER An immunie response to a drug examples: rash, itching, hives,
redness, swelling, bronchospasm or anaphylaxis
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