N677 Controlled Substance
Section 1: Controlled Substance Schedules (Questions 1–20)
1. Which of the following is a Schedule I controlled substance?
A. Codeine
B. Heroin
C. Amphetamine
D. Alprazolam
Answer: B. Heroin
Rationale: Heroin has no accepted medical use in the US and high abuse potential (Schedule
I). Codeine (with exceptions) is Schedule II–V depending on formulation; amphetamine is
Schedule II; alprazolam is Schedule IV.
2. A Schedule II drug must have a prescription that is:
A. Verbal, followed by written within 7 days
B. Electronic or written, no refills
C. Oral with unlimited refills
D. Written only, can be refilled twice
Answer: B. Electronic or written, no refills
Rationale: Schedule II requires written or e-prescription (with exceptions in emergencies).
No refills permitted. Verbal only allowed in emergencies with written follow-up within 7 days
– but that is not the standard rule.
3. Which schedule has the lowest abuse potential?
A. Schedule I
B. Schedule II
C. Schedule III
D. Schedule V
Answer: D. Schedule V
Rationale: Schedule V drugs (e.g., cough suppressants with codeine) have lowest abuse
potential among controlled substances; Schedule I highest.
4. Buprenorphine (alone) is classified as:
A. Schedule I
B. Schedule II
C. Schedule III
D. Schedule V
,Answer: C. Schedule III
Rationale: Buprenorphine has moderate abuse potential and is used for opioid use disorder;
it is Schedule III.
5. Which of the following is NOT a Schedule II drug?
A. Methadone
B. Oxycodone
C. Phentermine
D. Diazepam
Answer: D. Diazepam
Rationale: Diazepam (Valium) is Schedule IV. Methadone, oxycodone are Schedule II;
phentermine is Schedule IV (some formulations are Schedule III? No, phentermine is
Schedule IV – correct: phentermine is Schedule IV).
(Adjust: Phentermine is Schedule IV; thus D is correct Answer.)
6. A prescription for methylphenidate (Schedule II) can be refilled:
A. Up to 5 times within 6 months
B. Once within 30 days
C. Zero times
D. Unlimited with provider approval
Answer: C. Zero times
Rationale: No refills for Schedule II. Must obtain new prescription each time.
7. Which schedule allows for a prescription to be oral and refillable up to 5 times within 6
months?
A. Schedule II
B. Schedule III
C. Schedule IV
D. Schedules III, IV, and V
Answer: D. Schedules III, IV, and V
Rationale: Schedules III-V allow oral prescriptions (with limits) and up to 5 refills within 6
months.
8. A medication with accepted medical use, high abuse potential, and severe dependence
potential is:
A. Schedule I
B. Schedule II
C. Schedule III
D. Schedule IV
, Answer: B. Schedule II
Rationale: Schedule II = high abuse potential + accepted medical use + severe dependence
(e.g., morphine, oxycodone).
9. Which is Schedule IV?
A. Cocaine
B. Fentanyl
C. Lorazepam
D. Testosterone
Answer: C. Lorazepam
Rationale: Lorazepam (benzodiazepine) = Schedule IV. Cocaine, fentanyl = II; testosterone =
III.
10. Partial filling of Schedule II is allowed for long-term care facility patients:
A. True, up to 60 days
B. False, must be full fill
C. Only for hospice patients
D. Only if written by a pharmacist
Answer: A. True, up to 60 days
Rationale: For LTCF or terminal illness, partial filling is allowed with documentation, and total
quantity not exceeded within 60 days (DEA rule).
11. Which drug is Schedule I?
A. Marijuana (cannabis)
B. Hydrocodone
C. Carisoprodol
D. Pregabalin
Answer: A. Marijuana (cannabis)
Rationale: Federally Schedule I (though state laws vary). Hydrocodone = II; carisoprodol = IV;
pregabalin = V.
12. A Schedule V prescription for cough syrup with codeine:
A. Cannot be dispensed without a DEA form
B. May be refilled up to 5 times in 6 months
C. Requires a new prescription each month
D. Cannot be sold OTC in any state
Answer: B. May be refilled up to 5 times in 6 months
Rationale: Schedule V allows refills as above. Some states allow OTC sale of certain Schedule
V products (e.g., low-dose codeine) but federally prescription required.
13. The DEA requires that Schedule II prescriptions be signed and dated:
A. On the day of dispensing only
Section 1: Controlled Substance Schedules (Questions 1–20)
1. Which of the following is a Schedule I controlled substance?
A. Codeine
B. Heroin
C. Amphetamine
D. Alprazolam
Answer: B. Heroin
Rationale: Heroin has no accepted medical use in the US and high abuse potential (Schedule
I). Codeine (with exceptions) is Schedule II–V depending on formulation; amphetamine is
Schedule II; alprazolam is Schedule IV.
2. A Schedule II drug must have a prescription that is:
A. Verbal, followed by written within 7 days
B. Electronic or written, no refills
C. Oral with unlimited refills
D. Written only, can be refilled twice
Answer: B. Electronic or written, no refills
Rationale: Schedule II requires written or e-prescription (with exceptions in emergencies).
No refills permitted. Verbal only allowed in emergencies with written follow-up within 7 days
– but that is not the standard rule.
3. Which schedule has the lowest abuse potential?
A. Schedule I
B. Schedule II
C. Schedule III
D. Schedule V
Answer: D. Schedule V
Rationale: Schedule V drugs (e.g., cough suppressants with codeine) have lowest abuse
potential among controlled substances; Schedule I highest.
4. Buprenorphine (alone) is classified as:
A. Schedule I
B. Schedule II
C. Schedule III
D. Schedule V
,Answer: C. Schedule III
Rationale: Buprenorphine has moderate abuse potential and is used for opioid use disorder;
it is Schedule III.
5. Which of the following is NOT a Schedule II drug?
A. Methadone
B. Oxycodone
C. Phentermine
D. Diazepam
Answer: D. Diazepam
Rationale: Diazepam (Valium) is Schedule IV. Methadone, oxycodone are Schedule II;
phentermine is Schedule IV (some formulations are Schedule III? No, phentermine is
Schedule IV – correct: phentermine is Schedule IV).
(Adjust: Phentermine is Schedule IV; thus D is correct Answer.)
6. A prescription for methylphenidate (Schedule II) can be refilled:
A. Up to 5 times within 6 months
B. Once within 30 days
C. Zero times
D. Unlimited with provider approval
Answer: C. Zero times
Rationale: No refills for Schedule II. Must obtain new prescription each time.
7. Which schedule allows for a prescription to be oral and refillable up to 5 times within 6
months?
A. Schedule II
B. Schedule III
C. Schedule IV
D. Schedules III, IV, and V
Answer: D. Schedules III, IV, and V
Rationale: Schedules III-V allow oral prescriptions (with limits) and up to 5 refills within 6
months.
8. A medication with accepted medical use, high abuse potential, and severe dependence
potential is:
A. Schedule I
B. Schedule II
C. Schedule III
D. Schedule IV
, Answer: B. Schedule II
Rationale: Schedule II = high abuse potential + accepted medical use + severe dependence
(e.g., morphine, oxycodone).
9. Which is Schedule IV?
A. Cocaine
B. Fentanyl
C. Lorazepam
D. Testosterone
Answer: C. Lorazepam
Rationale: Lorazepam (benzodiazepine) = Schedule IV. Cocaine, fentanyl = II; testosterone =
III.
10. Partial filling of Schedule II is allowed for long-term care facility patients:
A. True, up to 60 days
B. False, must be full fill
C. Only for hospice patients
D. Only if written by a pharmacist
Answer: A. True, up to 60 days
Rationale: For LTCF or terminal illness, partial filling is allowed with documentation, and total
quantity not exceeded within 60 days (DEA rule).
11. Which drug is Schedule I?
A. Marijuana (cannabis)
B. Hydrocodone
C. Carisoprodol
D. Pregabalin
Answer: A. Marijuana (cannabis)
Rationale: Federally Schedule I (though state laws vary). Hydrocodone = II; carisoprodol = IV;
pregabalin = V.
12. A Schedule V prescription for cough syrup with codeine:
A. Cannot be dispensed without a DEA form
B. May be refilled up to 5 times in 6 months
C. Requires a new prescription each month
D. Cannot be sold OTC in any state
Answer: B. May be refilled up to 5 times in 6 months
Rationale: Schedule V allows refills as above. Some states allow OTC sale of certain Schedule
V products (e.g., low-dose codeine) but federally prescription required.
13. The DEA requires that Schedule II prescriptions be signed and dated:
A. On the day of dispensing only
