ASCP HEMATOLOGY EXAM REVIEW
WITH EXAM QUESTIONS AND
CORRECT SOLUTIONS||100%
GUARANTEED PASS||ALREADY
GRADED A+||UPDATED 2026/2027
SYLLABUS||<<RECENT VERSION>>
What is commonly seen in the blood smear of individuals who have hemoglobin
C? - ANSWER ✓ Hgb C crystals (bar shaped), target cells
In what condition is there a decrease or absence of the production of either beta or
alpha globin chains? - ANSWER ✓ thalassemia
What type of anemia is seen in individuals with beta thalassemia? - ANSWER ✓
microcytic hypochromic anemia
In individuals with beta thalassemia, what other hemoglobin types are produced to
make up for the lack of beta chain synthesis? What type of hemoglobin is
decreased in production (or absent)? - ANSWER ✓ A2 and F are increased, A is
decreased or absent
Individuals suffering from alpha thalassemia with 2 deleted alpha genes
experience what type of anemia? - ANSWER ✓ mild microcytic hypochromic
anemia
Hemoglobin H disease is characterized by the deletion of how many alpha genes?
- ANSWER ✓ 3
What type of anemia do individuals suffering from hemoglobin H disease
experience? - ANSWER ✓ chronic hemolytic anemia
Hgb Bart's may be present at birth in individuals suffering from what condition? -
ANSWER ✓ hemoglobin H disease
, 4 deleted alpha genes can result in the development of? - ANSWER ✓ hydrops
fetalis, nonviable fetus
What problems/conditions can lead to the development of microcytic
hypochromic anemia? - ANSWER ✓ iron deficiency, chronic disease
(inflammation), lead poisoning, thalassemia trait
What lab findings are commonly seen in iron deficiency anemia? - ANSWER ✓
decreased serum ferritin, iron, and % saturation and increased TIBC
What lab findings are commonly seen in anemia of chronic disease? - ANSWER
✓ decreased serum iron and TIBC and increased to normal serum ferritin
What lab findings are commonly seen in lead poisoning leading to a microcytic
hypochromic anemia? - ANSWER ✓ basophilic stippling, increased blood Pb
What lab findings are commonly seen in individuals who have the thalassemia
trait? - ANSWER ✓ normal serum iron and TIBC, increased A2 and F
What lab findings are commonly seen in individuals who have macrocytic
anemia? - ANSWER ✓ decreased folate/B12, retics and increased MMA,
homocysteine
What types of cells and inclusions are seen in individuals with a folate/B12
deficiency? - ANSWER ✓ macroovalocytes, hypersegmented neutrophils, howell
jolly bodies
A normal schilling test with IF indicates what type of problem or anemia? -
ANSWER ✓ pernicious anemia
An abnormal schilling test with or without IF indicates what type of problem or
anemia? - ANSWER ✓ malabsorption problem
An increase in liver enzymes, target cells, and round macrocytes can indicate what
conditions/problems? - ANSWER ✓ liver disease, alcholism
, What lab findings are commonly found in antibody mediated anemia? - ANSWER
✓ increased bilirubin, decreased haptoglobin, positive DAT
What conditions are associated with antibody mediated anemia? - ANSWER ✓
PCH, CAD, WAIHA
What type of antibody is associated with WAIHA-related anemia? - ANSWER ✓
IgG
What type of antibody is associated with CAD-related anemia? - ANSWER ✓
IgM with anti-I specificity
What type of antibody is associated with PCH-related anemia? - ANSWER ✓
anti-P
A positive Ham's test and a positive sucrose hemolysis test helps to diagnose what
condition - ANSWER ✓ PNH
A G6PD deficiency is characterized by what lab findings? - ANSWER ✓
decreased G6PD, heinz bodies
A PK deficiency is characterized by what lab findings? - ANSWER ✓ decreased
PK, no heinz bodies
What lab findings are commonly seen in individuals with aplastic anemia? -
ANSWER ✓ hypocellular bone marrow, decreased retics, panycytopenia
The osmotic fragility test measures? - ANSWER ✓ salt tolerance
Osmotic fragility is increased in what condition? - ANSWER ✓ hereditary
shperocytosis
Osmotic fragility is decreased in what condition? - ANSWER ✓ thalassemia
Ham's/Acid Hemolysis testing measures? - ANSWER ✓ complement mediated
lysis
WITH EXAM QUESTIONS AND
CORRECT SOLUTIONS||100%
GUARANTEED PASS||ALREADY
GRADED A+||UPDATED 2026/2027
SYLLABUS||<<RECENT VERSION>>
What is commonly seen in the blood smear of individuals who have hemoglobin
C? - ANSWER ✓ Hgb C crystals (bar shaped), target cells
In what condition is there a decrease or absence of the production of either beta or
alpha globin chains? - ANSWER ✓ thalassemia
What type of anemia is seen in individuals with beta thalassemia? - ANSWER ✓
microcytic hypochromic anemia
In individuals with beta thalassemia, what other hemoglobin types are produced to
make up for the lack of beta chain synthesis? What type of hemoglobin is
decreased in production (or absent)? - ANSWER ✓ A2 and F are increased, A is
decreased or absent
Individuals suffering from alpha thalassemia with 2 deleted alpha genes
experience what type of anemia? - ANSWER ✓ mild microcytic hypochromic
anemia
Hemoglobin H disease is characterized by the deletion of how many alpha genes?
- ANSWER ✓ 3
What type of anemia do individuals suffering from hemoglobin H disease
experience? - ANSWER ✓ chronic hemolytic anemia
Hgb Bart's may be present at birth in individuals suffering from what condition? -
ANSWER ✓ hemoglobin H disease
, 4 deleted alpha genes can result in the development of? - ANSWER ✓ hydrops
fetalis, nonviable fetus
What problems/conditions can lead to the development of microcytic
hypochromic anemia? - ANSWER ✓ iron deficiency, chronic disease
(inflammation), lead poisoning, thalassemia trait
What lab findings are commonly seen in iron deficiency anemia? - ANSWER ✓
decreased serum ferritin, iron, and % saturation and increased TIBC
What lab findings are commonly seen in anemia of chronic disease? - ANSWER
✓ decreased serum iron and TIBC and increased to normal serum ferritin
What lab findings are commonly seen in lead poisoning leading to a microcytic
hypochromic anemia? - ANSWER ✓ basophilic stippling, increased blood Pb
What lab findings are commonly seen in individuals who have the thalassemia
trait? - ANSWER ✓ normal serum iron and TIBC, increased A2 and F
What lab findings are commonly seen in individuals who have macrocytic
anemia? - ANSWER ✓ decreased folate/B12, retics and increased MMA,
homocysteine
What types of cells and inclusions are seen in individuals with a folate/B12
deficiency? - ANSWER ✓ macroovalocytes, hypersegmented neutrophils, howell
jolly bodies
A normal schilling test with IF indicates what type of problem or anemia? -
ANSWER ✓ pernicious anemia
An abnormal schilling test with or without IF indicates what type of problem or
anemia? - ANSWER ✓ malabsorption problem
An increase in liver enzymes, target cells, and round macrocytes can indicate what
conditions/problems? - ANSWER ✓ liver disease, alcholism
, What lab findings are commonly found in antibody mediated anemia? - ANSWER
✓ increased bilirubin, decreased haptoglobin, positive DAT
What conditions are associated with antibody mediated anemia? - ANSWER ✓
PCH, CAD, WAIHA
What type of antibody is associated with WAIHA-related anemia? - ANSWER ✓
IgG
What type of antibody is associated with CAD-related anemia? - ANSWER ✓
IgM with anti-I specificity
What type of antibody is associated with PCH-related anemia? - ANSWER ✓
anti-P
A positive Ham's test and a positive sucrose hemolysis test helps to diagnose what
condition - ANSWER ✓ PNH
A G6PD deficiency is characterized by what lab findings? - ANSWER ✓
decreased G6PD, heinz bodies
A PK deficiency is characterized by what lab findings? - ANSWER ✓ decreased
PK, no heinz bodies
What lab findings are commonly seen in individuals with aplastic anemia? -
ANSWER ✓ hypocellular bone marrow, decreased retics, panycytopenia
The osmotic fragility test measures? - ANSWER ✓ salt tolerance
Osmotic fragility is increased in what condition? - ANSWER ✓ hereditary
shperocytosis
Osmotic fragility is decreased in what condition? - ANSWER ✓ thalassemia
Ham's/Acid Hemolysis testing measures? - ANSWER ✓ complement mediated
lysis
