Pharmacology for Care of the Family
Latest Questions and Answers (2026) |
Updated Comprehensive Review with
Detailed Rationales | A+ Verified
• How does Phentermine and Diethylpropion promote weight loss? -✓✓-Promote weight
loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing
the availability of norepinephrine at receptors in the brain
• What is the maximum recommended duration of use for non-amphetamines? -✓✓3
months or less
• What drug schedule are Phentermine and Diethylpropion under? -✓✓Schedule IV
• What labs should be monitored with Phentermine and Diethylpropion? What condition
should we screen for? -✓✓-baseline CMP (watch electrolytes and creatinine)
-screen for depression
• Phentermine adverse effects -✓✓-increase HR and BP
-dry mouth and constipation
• What is role of topiramate in weight loss? -✓✓Increases satiety
• What are some Phentermine/topiramate contraindications for use? -✓✓not approved
in children and contraindicated with severe hepatic impairment
• How should we educate patient to take Phentermine/topiramate to avoid insomnia? -
✓✓given before 1600
• What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? -✓✓hx drug abuse, glaucoma, pregnant, HTN,
hyperthyroidism
• Phentermine/topiramate adverse effects -✓✓insomnia, nervousness, anxiety,
depression, blurred vision
• Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. -✓✓A) Glaucoma
B) Hypothyroidism
,C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
• Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat
by 30%. -✓✓GI tract
• Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may
not be absorbed well when taking Orlistat. -✓✓2
• Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. -✓✓12
• Orlistat results in the least amount of weight loss of all. How much? -✓✓2-3% body
weight (7 lbs in year)
• Orlistat adverse effects -✓✓Fecal incontinence, oily rectal leakage, flatus, abdominal
cramps. liver damage (light-colored stools, dark urine, fatigue, jaundice, anorexia)
• When is Orlistat contraindicated? -✓✓In those with malabsorption syndrome or
cholestasis
• What vitamin deficiency are we concerned about when taking Orlistat...especially if the
patient is on coumadin? -✓✓Monitor Coumadin as Vitamin K deficiency may occur and
intensify effect of Coumadin.
• A patient with a BMI of 27 would be considered: -✓✓overweight
• Lorcaserin adverse effects -✓✓headache, URI, back pain, hypoglycemia (in DM),
blood dyscrasias, cognitive impairment, psychiatric disorders, priapism, pulmonary
hypertension, and valvular heart disease
• Lorcaserin MOA -✓✓Reduces waist circumference, fasting glucose, insulin, total
cholesterol, LDL, triglycerides
• When is Lorcaserin contraindicated? -✓✓CrCl <30
-Not approved in children
• Lorcaserin drug interactions -✓✓-MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and
triptans
-Increased risk for serotonin syndrome
, • Naltrexone and Bupropion black box warning -✓✓increased risk for suicidal ideation
and suicide attempts in children, adolescents, and young adults
• Do not take Naltrexone and Bupropion within ___weeks of taking a _____. -✓✓-two
-MAOI
• Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what? -
✓✓opioids
• Naltrexone and Bupropion contraindications -✓✓HTN, seizure disorders, eating
disorders, alcohol or drug withdrawal
• Liraglutide MOA -✓✓-promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
• When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm -
✓✓10-20
-monitor for tachycardia
• When taking Liraglutide, monitor for ________ in patients with diabetes -
✓✓hypoglycemia
• Baseline labs for Liraglutide -✓✓lipids, CMP, HgA1C q 6 months, triglycerides
• Liraglutide black box warning -✓✓associated with a risk for thyroid C-cell tumors
based on studies in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2 (MEN 2)
or personal/family history of medullary thyroid carcinoma
• Those trying to LOSE weight should exercise at least ____ min/week or more -✓✓150
• What BMI is bariatric surgery considered? -✓✓35 or more
Common procedures:
-Gastric Bypass Surgery (Roux-en-Y procedure)
-Laparoscopic implantation of an adjustable gastric band
• What is typical weight loss for those who diligently adhere to medication and lifestyle
therapy?____% whereas >____% is exceptional -✓✓10-15%
> 15%
• Most weight loss occurs during the first ___ months of treatment -✓✓6