lOMoAR cPSD| 60399657
NSG223.08.01.01E3 1. Manifestations of Addison’s disease
Adrenal glands produce TOO LITTLE cortisol and TOO LITTLE
aldosterone (hormones control function of tissues or organs)
• Bronze skin, uneven body hair distribution, weight loss,
hypoglycemia, GI disturbances, weakness and postural
hypotension hypoglycemia, fatigue dehydration, low
sodium, and elevated potassium. Crave salt and be
dehydrated
• Addison’s Disease is when your adrenal glands, located
just above your kidneys produce too little cortisol and
often too little aldosterone. (Hormones control
function of tissues and organs).
• Cortisol: helps the body respond to stress, like surgery
or illness. It helps maintain BP, and heart function, the
immune system and blood glucose levels.
• Aldosterone: balance of sodium and potassium in the
blood. Controls the amount of urine removed which
effects BP and blood volume.
• The immune system mistakenly attacks your own
tissues damaging your adrenal glands. This can also be
caused by Cancer, TB, fungal infections and Genetic
changes.
NSG223.08.01.02.E3 2. Dietary education for patients with Addison’s disease
Diet high in protein
carbs sodium
NSG223.08.01.2.E3 3. Addisonian crisis—treatment
• Hydrocortisone IV push 1st action
then IV saline and dextrose 5%
• Vasopressors may be required if hypotension persists as well as
antibiotics if infection is present
NSG223.08.01.03.E3 4. Contraindications for patients w/Addison’s disease
on Hydrocortisone treatment
• NO LIVE VACCINES!
, lOMoAR cPSD| 60399657
Report swelling, weight gain, muscle weakness, tarry
Think Mr. Potato Head small extremities.
NSG223.08.02.03.E3
, lOMoAR cPSD| 60399657
face and jaw are enlarged
b. Gigantism
abnormally high linear growth due to the excessive action,
before the closure of the epiphyseal growth plates in
childhood
c. Dwarfism
insufficient secretion of GH during childhood can result in
generalized limited growth and pituitary dwarfism.
d. Panhypopituitarism
Undersecretion (hyposecretion) commonly involves all of the
anterior pituitary hormones and is termed
panhypopituitarism. In this condition, the thyroid gland, the
adrenal cortex, and the gonads atrophy (shrink) because of
loss of the tropic-stimulating hormones. Hypopituitarism may
result from destruction of the anterior lobe of the pituitary
gland
NSG223.08.02.04.E3 9. Ketoconazole (drug card) teaching points about this
drug
• Ketoconazole is absorbed rapidly in the GI tract. The drug is
protein bound. It is metabolized in the liver and excreted by
the kidneys.
• Ketoconazole acts by inhibiting the first step in cortisol
biosynthesis and the conversion of deoxycortisol to cortisol.
• Inhibits cortisol, take with water, coffee or food, or juice
WHICH ENHANCES THE ABSORPTION!
• Check BP, blood glucose, and NO ANTACIDS AT THE SAME
TIME, NCREASES ABSORPTION!! TAKE THEM IN BETWEEN
DOSES!!
NSG223.08.02.04.E3 10. Octreotide (drug card) – For acromegaly
• Supresses Gh and IGF-1, Treats diarrhea and GI
NSG223.08.01.01E3 1. Manifestations of Addison’s disease
Adrenal glands produce TOO LITTLE cortisol and TOO LITTLE
aldosterone (hormones control function of tissues or organs)
• Bronze skin, uneven body hair distribution, weight loss,
hypoglycemia, GI disturbances, weakness and postural
hypotension hypoglycemia, fatigue dehydration, low
sodium, and elevated potassium. Crave salt and be
dehydrated
• Addison’s Disease is when your adrenal glands, located
just above your kidneys produce too little cortisol and
often too little aldosterone. (Hormones control
function of tissues and organs).
• Cortisol: helps the body respond to stress, like surgery
or illness. It helps maintain BP, and heart function, the
immune system and blood glucose levels.
• Aldosterone: balance of sodium and potassium in the
blood. Controls the amount of urine removed which
effects BP and blood volume.
• The immune system mistakenly attacks your own
tissues damaging your adrenal glands. This can also be
caused by Cancer, TB, fungal infections and Genetic
changes.
NSG223.08.01.02.E3 2. Dietary education for patients with Addison’s disease
Diet high in protein
carbs sodium
NSG223.08.01.2.E3 3. Addisonian crisis—treatment
• Hydrocortisone IV push 1st action
then IV saline and dextrose 5%
• Vasopressors may be required if hypotension persists as well as
antibiotics if infection is present
NSG223.08.01.03.E3 4. Contraindications for patients w/Addison’s disease
on Hydrocortisone treatment
• NO LIVE VACCINES!
, lOMoAR cPSD| 60399657
Report swelling, weight gain, muscle weakness, tarry
Think Mr. Potato Head small extremities.
NSG223.08.02.03.E3
, lOMoAR cPSD| 60399657
face and jaw are enlarged
b. Gigantism
abnormally high linear growth due to the excessive action,
before the closure of the epiphyseal growth plates in
childhood
c. Dwarfism
insufficient secretion of GH during childhood can result in
generalized limited growth and pituitary dwarfism.
d. Panhypopituitarism
Undersecretion (hyposecretion) commonly involves all of the
anterior pituitary hormones and is termed
panhypopituitarism. In this condition, the thyroid gland, the
adrenal cortex, and the gonads atrophy (shrink) because of
loss of the tropic-stimulating hormones. Hypopituitarism may
result from destruction of the anterior lobe of the pituitary
gland
NSG223.08.02.04.E3 9. Ketoconazole (drug card) teaching points about this
drug
• Ketoconazole is absorbed rapidly in the GI tract. The drug is
protein bound. It is metabolized in the liver and excreted by
the kidneys.
• Ketoconazole acts by inhibiting the first step in cortisol
biosynthesis and the conversion of deoxycortisol to cortisol.
• Inhibits cortisol, take with water, coffee or food, or juice
WHICH ENHANCES THE ABSORPTION!
• Check BP, blood glucose, and NO ANTACIDS AT THE SAME
TIME, NCREASES ABSORPTION!! TAKE THEM IN BETWEEN
DOSES!!
NSG223.08.02.04.E3 10. Octreotide (drug card) – For acromegaly
• Supresses Gh and IGF-1, Treats diarrhea and GI
