WOUND FINAL EXAM 2026 WITH 100% ACCURATE ANSWERS
Section 1: Wound Healing Physiology (Q1–20)
Q1. Which phase of wound healing begins immediately after injury and lasts 3–5
days?
A. Proliferative
B. Remodeling
C. Inflammatory
D. Hemostasis
Answer: C. Inflammatory
Rationale: The inflammatory phase begins at injury, lasts 3–5 days, and involves
hemostasis and immune cell recruitment.
Q2. What is the primary cell type responsible for collagen deposition during
proliferative phase?
A. Neutrophils
B. Macrophages
,C. Fibroblasts
D. Keratinocytes
Answer: C. Fibroblasts
Rationale: Fibroblasts synthesize collagen and extracellular matrix, key for
granulation tissue formation.
Q3. Which growth factor is most critical for angiogenesis?
A. PDGF
B. VEGF
C. EGF
D. TGF-β
Answer: B. VEGF
Rationale: Vascular endothelial growth factor (VEGF) stimulates endothelial cell
proliferation and new blood vessel formation.
Q4. Wound strength at 3 weeks post-injury is approximately what percentage of
original tissue strength?
A. 10%
B. 20%
C. 50%
,D. 80%
Answer: B. 20%
Rationale: By 3 weeks, wound tensile strength is only ~20% of normal; full
strength takes up to 1 year.
Q5. Which vitamin deficiency most impairs collagen cross-linking?
A. Vitamin A
B. Vitamin C
C. Vitamin D
D. Vitamin E
Answer: B. Vitamin C
Rationale: Vitamin C (ascorbic acid) is a cofactor for prolyl and lysyl hydroxylase,
essential for collagen cross-linking.
Q6. What is the ideal moisture balance for wound healing?
A. Completely dry
B. Moist but not macerated
C. Soaked
D. Covered with eschar
Answer: B. Moist but not macerated
, Rationale: Moisture supports cell migration and autolytic debridement;
overhydration causes maceration.
Q7. Which cell type predominates in the early inflammatory phase (first 24
hours)?
A. Macrophages
B. Lymphocytes
C. Neutrophils
D. Mast cells
Answer: C. Neutrophils
Rationale: Neutrophils arrive first to phagocytose bacteria and debris.
Q8. Remodeling phase can last up to:
A. 2 weeks
B. 6 weeks
C. 6 months
D. 2 years
Answer: D. 2 years
Rationale: Remodeling (maturation) phase continues for months to 2 years,
reorganizing collagen.
Section 1: Wound Healing Physiology (Q1–20)
Q1. Which phase of wound healing begins immediately after injury and lasts 3–5
days?
A. Proliferative
B. Remodeling
C. Inflammatory
D. Hemostasis
Answer: C. Inflammatory
Rationale: The inflammatory phase begins at injury, lasts 3–5 days, and involves
hemostasis and immune cell recruitment.
Q2. What is the primary cell type responsible for collagen deposition during
proliferative phase?
A. Neutrophils
B. Macrophages
,C. Fibroblasts
D. Keratinocytes
Answer: C. Fibroblasts
Rationale: Fibroblasts synthesize collagen and extracellular matrix, key for
granulation tissue formation.
Q3. Which growth factor is most critical for angiogenesis?
A. PDGF
B. VEGF
C. EGF
D. TGF-β
Answer: B. VEGF
Rationale: Vascular endothelial growth factor (VEGF) stimulates endothelial cell
proliferation and new blood vessel formation.
Q4. Wound strength at 3 weeks post-injury is approximately what percentage of
original tissue strength?
A. 10%
B. 20%
C. 50%
,D. 80%
Answer: B. 20%
Rationale: By 3 weeks, wound tensile strength is only ~20% of normal; full
strength takes up to 1 year.
Q5. Which vitamin deficiency most impairs collagen cross-linking?
A. Vitamin A
B. Vitamin C
C. Vitamin D
D. Vitamin E
Answer: B. Vitamin C
Rationale: Vitamin C (ascorbic acid) is a cofactor for prolyl and lysyl hydroxylase,
essential for collagen cross-linking.
Q6. What is the ideal moisture balance for wound healing?
A. Completely dry
B. Moist but not macerated
C. Soaked
D. Covered with eschar
Answer: B. Moist but not macerated
, Rationale: Moisture supports cell migration and autolytic debridement;
overhydration causes maceration.
Q7. Which cell type predominates in the early inflammatory phase (first 24
hours)?
A. Macrophages
B. Lymphocytes
C. Neutrophils
D. Mast cells
Answer: C. Neutrophils
Rationale: Neutrophils arrive first to phagocytose bacteria and debris.
Q8. Remodeling phase can last up to:
A. 2 weeks
B. 6 weeks
C. 6 months
D. 2 years
Answer: D. 2 years
Rationale: Remodeling (maturation) phase continues for months to 2 years,
reorganizing collagen.
