Phobias & GAD | Q&A | Grade A | 100% Correct (Verified Answers) –
Champion Nursing Program
Subject: Psychiatric-Mental Health Nurse Practitioner (PMHNP) – Anxiety Disorders, GAD, Panic
Disorder, OCD, Phobias, Agoraphobia, Social Anxiety, Adjustment Disorder
Source: NR 547 Week 2 / DSM-5-TR / Clinical Practice Guidelines (2026/2027 Update)
Format: Q&A Guide with Clinical Rationales | Grade A Guaranteed
1. What is the most common mental illness in the United States?
Correct Answer: Anxiety disorders – impacting approximately 18% of adults and 25% of children ages
13-17 each year.
1. Anxiety disorders are the most prevalent psychiatric conditions in the U.S., exceeding
depression and substance use disorders.
2. Despite high prevalence, many cases remain underdiagnosed and undertreated in primary care
settings.
2. What is Obsessive-Compulsive Disorder (OCD) and its global impact?
Correct Answer: Characterized by persistent, uncontrollable thoughts or actions that occur over an
hour or more per day. One of the top 20 illness-related disabilities worldwide.
1. OCD is distinct from anxiety disorders in DSM-5 and resides in its own category of Obsessive-
Compulsive and Related Disorders.
2. First-line treatments include SSRIs and exposure with response prevention (ERP) therapy.
3. What is the first-line medication treatment for Generalized Anxiety Disorder (GAD) and
recommended duration?
Correct Answer: SSRIs, SNRIs, Buspirone. Drug therapy for at least 12 months.
1. SSRIs/SNRIs are preferred over benzodiazepines due to lower risk of dependence and
tolerance.
2. Long-term treatment (≥12 months) reduces relapse rates significantly.
4. What are the first-line medication treatments for Panic Disorder and recommended duration?
Correct Answer: Paroxetine, Sertraline, Fluoxetine. Drug therapy for 6-9 months.
1. SSRIs are first-line; benzodiazepines may be used as adjuncts for acute symptom management
but pose dependence risk.
2. Cognitive-behavioral therapy (CBT) is highly effective as monotherapy or combined with
medication.
, 5. What are the first-line medication treatments for Obsessive-Compulsive Disorder (OCD) and
recommended duration?
Correct Answer: Fluoxetine, Fluvoxamine, Sertraline, Paroxetine, Clomipramine (TCA). Drug therapy
for at least 1 year.
1. Clomipramine is a TCA that is highly effective but has more side effects; SSRIs are generally
preferred as first-line.
2. High-dose SSRIs (often above FDA-approved depression doses) are typically required for
OCD.
6. What are the first-line medication treatments for Social Anxiety Disorder and onset of effects?
Correct Answer: Sertraline, Paroxetine. Drug therapy takes 4 weeks to see effects.
1. Beta-blockers (propranolol) are used for performance-only social anxiety when taken 30-60
minutes before the event.
2. CBT is also highly effective for SAD and may be used alone or with medication.
7. What are the first-line medication treatments for Post-Traumatic Stress Disorder (PTSD)?
Correct Answer: Paroxetine, Sertraline
1. These are the only two FDA-approved SSRIs for PTSD. Trauma-focused psychotherapies
(CBT, EMDR) are also first-line.
8. Anxiety is often comorbid with which conditions?
Correct Answer: Major depression, COPD, asthma, diabetes
1. Comorbid anxiety worsens outcomes for medical conditions and requires integrated treatment
approaches.
9. Describe the neurological basis of Generalized Anxiety Disorder (GAD).
Correct Answer: Neurological condition characterized by persistent, uncontrollable worrying causing
emotional distress. Symptoms occur most days for ≥6 months. Common symptoms: restlessness,
irritability, muscle tension, fatigue, sleep disturbances. Twice as common in women.
1. GAD is associated with dysfunction in the cortico-striatal-thalamo-cortical (CSTC) circuits.
10. Patients with anxiety disorders often show increased activity in which brain regions?
Correct Answer: Amygdala and prefrontal cortex
1. Hyperactivation of the amygdala mediates fear response; reduced PFC activity impairs top-
down regulation of anxiety.
11. What do PET scans show in patients with anxiety?
Correct Answer: Reduced serotonin binding
1. Reduced serotonin binding supports the rationale for using SSRIs as first-line treatment for
anxiety disorders.