NSG6005 WEEK 1,2,3 AND 5 QUIZ
ADVANCED PHARMACOLOGY SOUTH
UNIVERSITY VERIFIED QUESTIONS
WITH CORRECT ANSWERS
\Q\.The major reason for not crushing a sustained release capsule is that, if
crushed, the coated beads of the drugs could possibly result in:
o Disintegration
o Toxicity
o Malabsorption
o Deterioration - ANSWER-✔o Toxicity
\Q\.Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only o Bypass the hepatic
circulation o Are rapidly metabolized by the liver and may have
little if any desired action
o Are converted by the liver to more active in fat-soluble forms -
ANSWER-✔o Are rapidly metabolized by the liver and may have
little if any desired action
,\Q\.When obtaining a drug history from Harold, he gives you a complete list of his
prescription medications. He denies taking any other drugs, but you find that he
occasionally takes aspirin for his arthritis flare-ups. This is an example of:
o His appropriately only telling you about his regularly prescribed
medications o His hiding information regarding his inappropriate
use of aspirin from you
o His common misconception that intermittently taking OTC
medications are not an important part of his drug history
o A common misuse of OTC aspirin - ANSWER-✔o His common
misconception that intermittently taking OTC medications are not
an important part of his drug history
\Q\.Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug o Inhibit the metabolism
of another drug o Both A and B o Neither A nor B - ANSWER-✔o
Both A and B
\Q\.A twenty four year old male received multiple fractures in a motor vehicle
accident that required significant amounts of opioid medication to treat his pain.
He is at risk for Type ____ ADR when he no longer requires the opioids.
oAoCoE
o G - ANSWER-✔o E
,\Q\.Infants and young children are at higher risk of ADRs due to:
o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population o
Children's skin being thicker than adults, requiring higher dosages
of topical medication o Infant boys having a higher proportion of
muscle mass, leading to a higher volume of distribution -
ANSWER-✔o Lack of safety and efficacy studies in the pediatric
population
\Q\.The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic dose is:
o Type A o Type B o Type C o Type D - ANSWER-✔o Type A
\Q\.A nurse practitioner would prescribe the liquid form of ibuprofen for a six-
year-old because:
o Drugs given in liquid form are less irritating to the stomach. o A
six-year-old may have problems swallowing a pill. o Liquid forms
of medication eliminate the concern for first-pass effect.
, o Liquid ibuprofen does not have to be dosed as often as tablet
form. - ANSWER-✔o A six-yearold may have problems swallowing
a pill.
\Q\.The role of the nurse practitioner in the use of herbal medication is to:
o Maintain competence in the prescribing of common herbal
remedies. o Recommend common OTC herbs to patients. o
Educate patients and guide them to appropriate sources of care.
o Encourage patients to not use herbal therapy due to the
documented dangers. - ANSWER-✔o Educate patients and guide
them to appropriate sources of care.
\Q\.Genetic polymorphisms account for differences in metabolism, including:
o Poor metabolizers (PMs) that lack a working enzyme o
Intermediate metabolizers (IMs) that have one working, wild-type
allele and one mutant allele o Extensive metabolizers (EMs), with
two normally functioning alleles o All of the above - ANSWER-✔o
All of the above
\Q\.The elderly are at high risk of ADRs due to:
ADVANCED PHARMACOLOGY SOUTH
UNIVERSITY VERIFIED QUESTIONS
WITH CORRECT ANSWERS
\Q\.The major reason for not crushing a sustained release capsule is that, if
crushed, the coated beads of the drugs could possibly result in:
o Disintegration
o Toxicity
o Malabsorption
o Deterioration - ANSWER-✔o Toxicity
\Q\.Drugs that have a significant first pass effect:
o Must be given by enteral (oral) route only o Bypass the hepatic
circulation o Are rapidly metabolized by the liver and may have
little if any desired action
o Are converted by the liver to more active in fat-soluble forms -
ANSWER-✔o Are rapidly metabolized by the liver and may have
little if any desired action
,\Q\.When obtaining a drug history from Harold, he gives you a complete list of his
prescription medications. He denies taking any other drugs, but you find that he
occasionally takes aspirin for his arthritis flare-ups. This is an example of:
o His appropriately only telling you about his regularly prescribed
medications o His hiding information regarding his inappropriate
use of aspirin from you
o His common misconception that intermittently taking OTC
medications are not an important part of his drug history
o A common misuse of OTC aspirin - ANSWER-✔o His common
misconception that intermittently taking OTC medications are not
an important part of his drug history
\Q\.Drugs that use CYP3A4 isoenzymes for metabolism may:
o Induce the metabolism of another drug o Inhibit the metabolism
of another drug o Both A and B o Neither A nor B - ANSWER-✔o
Both A and B
\Q\.A twenty four year old male received multiple fractures in a motor vehicle
accident that required significant amounts of opioid medication to treat his pain.
He is at risk for Type ____ ADR when he no longer requires the opioids.
oAoCoE
o G - ANSWER-✔o E
,\Q\.Infants and young children are at higher risk of ADRs due to:
o Immature renal function in schoolage children
o Lack of safety and efficacy studies in the pediatric population o
Children's skin being thicker than adults, requiring higher dosages
of topical medication o Infant boys having a higher proportion of
muscle mass, leading to a higher volume of distribution -
ANSWER-✔o Lack of safety and efficacy studies in the pediatric
population
\Q\.The type of ADR that is the result of an unwanted but otherwise normal
pharmacological action of a drug given in the usual therapeutic dose is:
o Type A o Type B o Type C o Type D - ANSWER-✔o Type A
\Q\.A nurse practitioner would prescribe the liquid form of ibuprofen for a six-
year-old because:
o Drugs given in liquid form are less irritating to the stomach. o A
six-year-old may have problems swallowing a pill. o Liquid forms
of medication eliminate the concern for first-pass effect.
, o Liquid ibuprofen does not have to be dosed as often as tablet
form. - ANSWER-✔o A six-yearold may have problems swallowing
a pill.
\Q\.The role of the nurse practitioner in the use of herbal medication is to:
o Maintain competence in the prescribing of common herbal
remedies. o Recommend common OTC herbs to patients. o
Educate patients and guide them to appropriate sources of care.
o Encourage patients to not use herbal therapy due to the
documented dangers. - ANSWER-✔o Educate patients and guide
them to appropriate sources of care.
\Q\.Genetic polymorphisms account for differences in metabolism, including:
o Poor metabolizers (PMs) that lack a working enzyme o
Intermediate metabolizers (IMs) that have one working, wild-type
allele and one mutant allele o Extensive metabolizers (EMs), with
two normally functioning alleles o All of the above - ANSWER-✔o
All of the above
\Q\.The elderly are at high risk of ADRs due to:
