NSG 533 Opioid Quiz
Comprehensive Questions
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Answers Graded A+
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Endogenous opioid peptides - Answer: Small molecules that are
naturally produced in the CNS and in various glands throughout the
body, such as the pituitary and adrenal glands. Consists of endorphins,
enkephalins, dynorphins, and nociceptins.
, Mechanism of action for opioids - Answer: Stimulating opioid u-
receptors in the CNS. Pure agonists (morphine) bind to u-receptors to
produce analgesia that increases with dose without a ceiling effect.
Partial agonists at the u-receptor (Buprenorphine, tramadol) cause less
conformational change and receptor activation than full agonists.
Indications for initiating opioid therapy - Answer: Used when benefits
outweigh risks associated with opioids such as abuse. Used for acute
pain (including post-surgical) from under a month, and chronic pain.
Tolerance - Answer: the diminishing effect with regular use of the same
dose of a drug, requiring the user to take larger and larger doses before
experiencing the drug's effect
Dependence - Answer: the condition that results when the brain
develops a chemical need for a drug and cannot function normally
without it
Addiction - Answer: A physiological or psychological dependence on a
drug
Neuralgia - Answer: nerve pain
Analgesia - Answer: Pain relief; inability to feel pain
Comprehensive Questions
(Frequently Tested) with Verified
Answers Graded A+
Professional Academic Assistance Services
Services Offered
• Proctored Exam Assistance
• Online Class Management (Full Course Support)
• Exam Preparation & Study Materials
• Assignments and Coursework Support
• Essay and Research Paper Writing
• Discussion Posts & Responses
• Editing and Proofreading
• Confidential Academic Consultation
Helping Students Achieve Academic Excellence
Endogenous opioid peptides - Answer: Small molecules that are
naturally produced in the CNS and in various glands throughout the
body, such as the pituitary and adrenal glands. Consists of endorphins,
enkephalins, dynorphins, and nociceptins.
, Mechanism of action for opioids - Answer: Stimulating opioid u-
receptors in the CNS. Pure agonists (morphine) bind to u-receptors to
produce analgesia that increases with dose without a ceiling effect.
Partial agonists at the u-receptor (Buprenorphine, tramadol) cause less
conformational change and receptor activation than full agonists.
Indications for initiating opioid therapy - Answer: Used when benefits
outweigh risks associated with opioids such as abuse. Used for acute
pain (including post-surgical) from under a month, and chronic pain.
Tolerance - Answer: the diminishing effect with regular use of the same
dose of a drug, requiring the user to take larger and larger doses before
experiencing the drug's effect
Dependence - Answer: the condition that results when the brain
develops a chemical need for a drug and cannot function normally
without it
Addiction - Answer: A physiological or psychological dependence on a
drug
Neuralgia - Answer: nerve pain
Analgesia - Answer: Pain relief; inability to feel pain
