EXAM 1 TWU 5663 PHARMACOLOGY QUESTIONS AND
VERIFIED ANSWERS |100% CORRECT | ALREADY GRADED
A
Name the 4 types of bonds Correct Answers Covalent, ionic, hydrogen,
vanderwaals
What is the strongest type of bond? Correct Answers Covalent
What is the weakest type of bond? Correct Answers Vanderwaals
Pharmokinetics Correct Answers The study of drug movement
throughout the body; how the body affects drugs
]Pharmacodynamics Correct Answers The study of the biochemical and
physiologic effects of drugs and the molecular mechanisms by which
those effects are produced
What drugs do to the body and how they do it
Absorption Correct Answers The movement of a drug from its site of
administration into the blood
PO, Parental, transdermal, rectal, etc.
Distribution Correct Answers a drugs movement from blood to
interstitial space of tissues and into the cells
speed is increased by greater blood flow
, fat soluble drugs distribute easily compared to water soluble
metabolism or biotransformation Correct Answers The enzymatically
mediated alteration of drug structure
e.g. codeine transforming to morphine
phase 1 metabolism Correct Answers mediated by CYP 450
converts non-polar lipid-soluble medications into polar water soluble
metabolites through oxidation, reduction, or hydrolysis
phase 2 metabolism Correct Answers Conjugation reactions in which
medications are joined with another compound which makes it more
polar and easier to be excreted via the kidneys
Groups of compounds: Methyl, acetyl, sulfa, glutathione, glucoride,
amino acid
poor metabolizers Correct Answers less enzymes causing them to be
slower and less effective w/ certain meds
meds build in body and cause dangerous side effects
rapid metabolizers Correct Answers more difficult to achieve a high
level of meds
more likely to experience adverse effects
potency Correct Answers how strong a drug is at a particular dose
VERIFIED ANSWERS |100% CORRECT | ALREADY GRADED
A
Name the 4 types of bonds Correct Answers Covalent, ionic, hydrogen,
vanderwaals
What is the strongest type of bond? Correct Answers Covalent
What is the weakest type of bond? Correct Answers Vanderwaals
Pharmokinetics Correct Answers The study of drug movement
throughout the body; how the body affects drugs
]Pharmacodynamics Correct Answers The study of the biochemical and
physiologic effects of drugs and the molecular mechanisms by which
those effects are produced
What drugs do to the body and how they do it
Absorption Correct Answers The movement of a drug from its site of
administration into the blood
PO, Parental, transdermal, rectal, etc.
Distribution Correct Answers a drugs movement from blood to
interstitial space of tissues and into the cells
speed is increased by greater blood flow
, fat soluble drugs distribute easily compared to water soluble
metabolism or biotransformation Correct Answers The enzymatically
mediated alteration of drug structure
e.g. codeine transforming to morphine
phase 1 metabolism Correct Answers mediated by CYP 450
converts non-polar lipid-soluble medications into polar water soluble
metabolites through oxidation, reduction, or hydrolysis
phase 2 metabolism Correct Answers Conjugation reactions in which
medications are joined with another compound which makes it more
polar and easier to be excreted via the kidneys
Groups of compounds: Methyl, acetyl, sulfa, glutathione, glucoride,
amino acid
poor metabolizers Correct Answers less enzymes causing them to be
slower and less effective w/ certain meds
meds build in body and cause dangerous side effects
rapid metabolizers Correct Answers more difficult to achieve a high
level of meds
more likely to experience adverse effects
potency Correct Answers how strong a drug is at a particular dose
