MSN 604: TEST 1 QUESTIONS WITH 100% ACCURATE
SOLUTIONS
1) What happens to the reward circuitry with repetitive substance use? -- Answer
✔✔ It leads to neuroadaptation, where the brain produces less dopamine or
eliminates receptors, resulting in anhedonia.
2) What is anhedonia? -- Answer ✔✔ The inability to feel pleasure, often a
symptom of depression or a result of neuroadaptation in substance use disorders.
3) Which brain structures are involved in conditioned responses related to
addiction? -- Answer ✔✔ The amygdala and hippocampus, which store
environmental triggers that cause cravings.
4) What are the effects of alcohol on neurotransmitters? -- Answer ✔✔ Alcohol
affects GABA (inhibitory) and Glutamate (excitatory).
5) What severe withdrawal symptoms can occur with alcohol? -- Answer ✔✔ Life-
threatening seizures and hallucinations, known as Delirium Tremens.
, 6) What receptors do opioids bind to? -- Answer ✔✔ Mu-opioid receptors.
7) What are common illicit opioids? -- Answer ✔✔ Fentanyl and heroin.
8) What are maintenance treatments for opioid addiction? -- Answer ✔✔
Methadone (full agonist) and Buprenorphine (partial agonist).
9) What is the psychoactive component of cannabis? -- Answer ✔✔ THC.
10) What is the SBIRT model? -- Answer ✔✔ Screening, Brief Intervention, and
Referral to Treatment.
11) What is Motivational Interviewing (MI)? -- Answer ✔✔ A person-centered
communication style that uses OARS (Open-ended questions, Affirmations,
Reflections, Summaries) to foster motivation for change.
12) What is harm reduction in addiction treatment? -- Answer ✔✔ Strategies aimed
at reducing negative consequences rather than strictly requiring abstinence, such
as Naloxone for overdose reversal.
13) What are SSRIs used for? -- Answer ✔✔ They are first-line treatments for
depression and anxiety.
14) What is a Black-Box Warning? -- Answer ✔✔ The strictest warning mandated by
the FDA for drugs with serious hazards, particularly regarding increased risk of
suicidal thoughts/behaviors in individuals under 25.
SOLUTIONS
1) What happens to the reward circuitry with repetitive substance use? -- Answer
✔✔ It leads to neuroadaptation, where the brain produces less dopamine or
eliminates receptors, resulting in anhedonia.
2) What is anhedonia? -- Answer ✔✔ The inability to feel pleasure, often a
symptom of depression or a result of neuroadaptation in substance use disorders.
3) Which brain structures are involved in conditioned responses related to
addiction? -- Answer ✔✔ The amygdala and hippocampus, which store
environmental triggers that cause cravings.
4) What are the effects of alcohol on neurotransmitters? -- Answer ✔✔ Alcohol
affects GABA (inhibitory) and Glutamate (excitatory).
5) What severe withdrawal symptoms can occur with alcohol? -- Answer ✔✔ Life-
threatening seizures and hallucinations, known as Delirium Tremens.
, 6) What receptors do opioids bind to? -- Answer ✔✔ Mu-opioid receptors.
7) What are common illicit opioids? -- Answer ✔✔ Fentanyl and heroin.
8) What are maintenance treatments for opioid addiction? -- Answer ✔✔
Methadone (full agonist) and Buprenorphine (partial agonist).
9) What is the psychoactive component of cannabis? -- Answer ✔✔ THC.
10) What is the SBIRT model? -- Answer ✔✔ Screening, Brief Intervention, and
Referral to Treatment.
11) What is Motivational Interviewing (MI)? -- Answer ✔✔ A person-centered
communication style that uses OARS (Open-ended questions, Affirmations,
Reflections, Summaries) to foster motivation for change.
12) What is harm reduction in addiction treatment? -- Answer ✔✔ Strategies aimed
at reducing negative consequences rather than strictly requiring abstinence, such
as Naloxone for overdose reversal.
13) What are SSRIs used for? -- Answer ✔✔ They are first-line treatments for
depression and anxiety.
14) What is a Black-Box Warning? -- Answer ✔✔ The strictest warning mandated by
the FDA for drugs with serious hazards, particularly regarding increased risk of
suicidal thoughts/behaviors in individuals under 25.
