QUESTIONS AND VERIFIED ANSWERS
●● alcohol dependence
Answer: FDA approved disulfiram, naltrexone, and acamprosate for
treatment of ____________
●● opioid dependence
Answer: FDA approved methadone, naltrexone, and buprenorphine for
treatment of _____________
●● alcohol, nicotine and opioid
Answer: currently, FDA has approved medications effective for MAT in
three types of SUD: _____________, _____________ and __________
dependence
●● acamprosate, disulfiram, naltrexone
Answer: three drugs approved for alcohol dependence
●● Acamprosate (Campral)
Answer: used to treat alcohol dependence; reduces symptoms of
protracted withdrawal (i.e. insomnia, anxiety, restlessness, and
,dysphoria) by normalizing brain systems disrupted by chronic alcohol
consumption; more effective in pts with severe alcohol use disorders
●● Disulfiram (Antabuse)
Answer: used to treat alcohol dependence; inhibits an enzyme involved
in the metabolism in alcohol, causing unpleasant reaction (i.e. flushing,
nausea, and heart palpitations) if alcohol is consumed after taking the
medication; compliance can be a problem but is very effective with
motivated pts.
●● Naltrexone (Vivitrol or Revia)
Answer: used to treat alcohol dependence; blocks receptors involved in
rewarding effects of drinking and in cravings for alcohol. Reduces
relapse of heavy drinking behavior and is highly effective in some but
not all pts., where varied outcomes could be due to genetic factors.
Available in both oral tablet and long-acting injectable form
●● Methadone, Buprenorphine, Naltrexone
Answer: three FDA approved drugs used in MAT for opioid use
disorders
●● Methadone
Answer: prevents opioid withdrawal and craving symptoms by
activating opiate receptors in the brain. Long history of use in treatment
of opioid dependence.
, ●● Buprenorphine
Answer: reduces or eliminates opioid withdrawal symptoms and reduces
cravings, without producing euphoria or dangerous side effects of heroin
or other opioids. Activates and blocks opioid receptors in the brain.
Available for sublingual administration in both a stand-alone formula
and in combination with naloxone.
●● Naltrexone (Vivitrol or Revia)
Answer: approved for prevention of relapse in adult pts. following
complete detox from opioids. Acts by blocking brain's opioid receptors,
preventing opioid drugs from acting on them and thus blocking euphoria
the user would normally feel and/or causing withdrawal if recent opioid
use has occurred. Can be taken orally or given in monthly injections
●● Naloxone (Narcan)
Answer: medication used to prevent opioid overdose deaths. Medication
binds to opioid receptors and can rapidly reverse or block the effects of
other opioids.
●● Individual therapy
Answer: form of behavioral therapy that can help people learn new skills
to maintain a substance-free life, address co-occurring mental health
issues, address benefits of using prescription medication in treatment,
and support individuals to pursue meaningful work, school, and family
goals