ANCC FNP BOARD EXAM NEWEST 2026 ACTUAL
EXAM TEST BANK| FAMILY NURSING
PRACTITIONER ANCC BOARD EXAM PREP WITH
COMPLETE 350 REAL EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+ (MOST RECENT!!)
Which hematologic findings on a peripheral smear support a diagnosis
of sickle cell anemia? (Select all that apply.)
A. Burr cells
B. Target cells
C. Schistocytes
D. Howell-Jolly bodies
E. Anisopoikilocytosis – Correct Answer - B, D
Target cells and Howell–Jolly bodies are found on a peripheral smear in
patients with sickle cell anemia. Burr cells and schistocytes are cell
shapes categorized as poikilocytosis. Anisopoikilocytosis is associated
with beta thalassemia major, not sickle cell anemia.
A nurse practitioner assesses a child who is experiencing severe otalgia
and has a temperature of 100.7°F. The Rinne test result shows BC > AC,
and the Weber exam shows lateralization in the affected ear. The nurse
practitioner notes blisters on an erythematic tympanic membrane (TM).
Which of the following conditions is most likely?
A. Acute otitis media (AOM)
B. Otitis media with effusion
C. Bullous myringitis
pg. 1
,D. Otitis externa – Correct Answer - C
Bullous myringitis is a severe type of AOM with painful blisters (bullae)
on a reddened TM. The patient may exhibit conductive hearing loss,
otalgia, muffled hearing, and a low-grade fever. With otitis media with
effusion, the TM may bulge or retract, but it is not red. It may follow
AOM and be caused by chronic allergic rhinitis. Otitis externa
(swimmer’s ear) is more common in the warm and humid seasons. There
is external otalgia, swelling, discharge, pruritus, and hearing loss if the
canal is blocked with pus.
Your patient is a 65-year-old man who has been taking a new
prescription of rosuvastatin (Crestor) 40 mg daily for 6 weeks. During a
follow-up visit, he reports feeling extremely fatigued and having dark-
colored urine. He denies any generalized muscle soreness."
Which of the following is the most appropriate treatment plan?
A. Order a complete blood count (CBC) with differential
B. Order a liver function profile and creatine kinase (CK) level
C. Recommend an increase in fluid intake and rest
D. Order a urine culture and sensitivity test – Correct Answer - B
Statin medications such as rosuvastatin (Crestor) can affect liver
function and increase liver enzymes, as well as cause the patient to feel
weak and fatigued and have muscle aches. Therefore, checking the liver
function profile is recommended.
A 15-year-old boy has just moved into the community and is staying in a
foster home temporarily. There is no record of his immunizations. His
foster mother wants him to be checked before he enters the local high
school. Which of the following immunizations does this patient need?
A. Meningococcal vaccine
pg. 2
,B. Measles-mumps-rubella (MMR) vaccine
C. Tdap vaccine
D. All of the above – Correct Answer - D
This 15-year-old teenage patient will follow the Centers for Disease
Control and Prevention (CDC) “catch-up” schedule and needs the
meningococcal vaccine, MMR vaccine, and Tdap vaccine. In addition to
these three vaccines, this patient needs the hepatitis B vaccine, human
papillomavirus (HPV) vaccine, and varicella vaccine (if no history of
chickenpox).
Systemic lupus erythematosus (SLE) is more common among female
patients from all of the following ethnic and racial backgrounds, except:
A. African American
B. Asian
C. Hispanic
D. Caucasian – Correct Answer - D
Lupus is two to three times more prevalent among women of African
American, Asian, Hispanic, and Native American backgrounds than in
Caucasian women.
A 55-year-old male patient describes an episode of chest tightness in his
substernal area that radiated to his back while he was jogging. It was
relieved immediately when he stopped. The patient's symptoms are
highly suggestive of which condition?
A. Angina pectoris
B. Acute myocardial infarction (MI)
C. Gastroesophageal reflux disease
D. Acute costochondritis – Correct Answer - A
pg. 3
, The classic pain of angina is described as discomfort, pressure, tightness,
or heaviness on the center or left side of the chest that is precipitated by
exertion and relieved by rest. The pain can be referred to the back,
shoulders, neck, or jaw. The pain is not sharp, knife like, or stabbing in
nature. Angina is caused by transient myocardial ischemia. The most
common cause of angina is coronary artery disease. If the angina
worsens, is not relieved by rest, or lasts more than 20 minutes, it may be
due to acute MI. If acute MI is suspected, call 911.
The nurse practitioner recently increased a patient's antipsychotic
medication and is assessing the patient in a follow-up appointment. All
of the following symptoms suggest the patient is experiencing malignant
neuroleptic syndrome, except:
A. Headache
B. Tremors
C. Muscular rigidity
D. Fever – Correct Answer - A
Malignant neuroleptic syndrome is characterized by muscular rigidity,
tremors, difficulty swallowing, fever, hypertension, mental status
changes, and diaphoresis. Headache is not a manifestation of malignant
neuroleptic syndrome and would not contribute to confirmation of this
diagnosis.
A sexually active young adult is diagnosed with Chlamydia trachomatis
and treated with doxycycline 100 mg BID 7 days. During a follow-up
visit, the patient reports a new onset of right upper quadrant pain and
tenderness on palpation. Alanine aminotransferase (ALT) is 43 U/L, and
aspartate aminotransferase (AST) is 24 U/L. The nurse practitioner
suspects:
A. Jarisch–Herxheimer reaction
pg. 4
EXAM TEST BANK| FAMILY NURSING
PRACTITIONER ANCC BOARD EXAM PREP WITH
COMPLETE 350 REAL EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+ (MOST RECENT!!)
Which hematologic findings on a peripheral smear support a diagnosis
of sickle cell anemia? (Select all that apply.)
A. Burr cells
B. Target cells
C. Schistocytes
D. Howell-Jolly bodies
E. Anisopoikilocytosis – Correct Answer - B, D
Target cells and Howell–Jolly bodies are found on a peripheral smear in
patients with sickle cell anemia. Burr cells and schistocytes are cell
shapes categorized as poikilocytosis. Anisopoikilocytosis is associated
with beta thalassemia major, not sickle cell anemia.
A nurse practitioner assesses a child who is experiencing severe otalgia
and has a temperature of 100.7°F. The Rinne test result shows BC > AC,
and the Weber exam shows lateralization in the affected ear. The nurse
practitioner notes blisters on an erythematic tympanic membrane (TM).
Which of the following conditions is most likely?
A. Acute otitis media (AOM)
B. Otitis media with effusion
C. Bullous myringitis
pg. 1
,D. Otitis externa – Correct Answer - C
Bullous myringitis is a severe type of AOM with painful blisters (bullae)
on a reddened TM. The patient may exhibit conductive hearing loss,
otalgia, muffled hearing, and a low-grade fever. With otitis media with
effusion, the TM may bulge or retract, but it is not red. It may follow
AOM and be caused by chronic allergic rhinitis. Otitis externa
(swimmer’s ear) is more common in the warm and humid seasons. There
is external otalgia, swelling, discharge, pruritus, and hearing loss if the
canal is blocked with pus.
Your patient is a 65-year-old man who has been taking a new
prescription of rosuvastatin (Crestor) 40 mg daily for 6 weeks. During a
follow-up visit, he reports feeling extremely fatigued and having dark-
colored urine. He denies any generalized muscle soreness."
Which of the following is the most appropriate treatment plan?
A. Order a complete blood count (CBC) with differential
B. Order a liver function profile and creatine kinase (CK) level
C. Recommend an increase in fluid intake and rest
D. Order a urine culture and sensitivity test – Correct Answer - B
Statin medications such as rosuvastatin (Crestor) can affect liver
function and increase liver enzymes, as well as cause the patient to feel
weak and fatigued and have muscle aches. Therefore, checking the liver
function profile is recommended.
A 15-year-old boy has just moved into the community and is staying in a
foster home temporarily. There is no record of his immunizations. His
foster mother wants him to be checked before he enters the local high
school. Which of the following immunizations does this patient need?
A. Meningococcal vaccine
pg. 2
,B. Measles-mumps-rubella (MMR) vaccine
C. Tdap vaccine
D. All of the above – Correct Answer - D
This 15-year-old teenage patient will follow the Centers for Disease
Control and Prevention (CDC) “catch-up” schedule and needs the
meningococcal vaccine, MMR vaccine, and Tdap vaccine. In addition to
these three vaccines, this patient needs the hepatitis B vaccine, human
papillomavirus (HPV) vaccine, and varicella vaccine (if no history of
chickenpox).
Systemic lupus erythematosus (SLE) is more common among female
patients from all of the following ethnic and racial backgrounds, except:
A. African American
B. Asian
C. Hispanic
D. Caucasian – Correct Answer - D
Lupus is two to three times more prevalent among women of African
American, Asian, Hispanic, and Native American backgrounds than in
Caucasian women.
A 55-year-old male patient describes an episode of chest tightness in his
substernal area that radiated to his back while he was jogging. It was
relieved immediately when he stopped. The patient's symptoms are
highly suggestive of which condition?
A. Angina pectoris
B. Acute myocardial infarction (MI)
C. Gastroesophageal reflux disease
D. Acute costochondritis – Correct Answer - A
pg. 3
, The classic pain of angina is described as discomfort, pressure, tightness,
or heaviness on the center or left side of the chest that is precipitated by
exertion and relieved by rest. The pain can be referred to the back,
shoulders, neck, or jaw. The pain is not sharp, knife like, or stabbing in
nature. Angina is caused by transient myocardial ischemia. The most
common cause of angina is coronary artery disease. If the angina
worsens, is not relieved by rest, or lasts more than 20 minutes, it may be
due to acute MI. If acute MI is suspected, call 911.
The nurse practitioner recently increased a patient's antipsychotic
medication and is assessing the patient in a follow-up appointment. All
of the following symptoms suggest the patient is experiencing malignant
neuroleptic syndrome, except:
A. Headache
B. Tremors
C. Muscular rigidity
D. Fever – Correct Answer - A
Malignant neuroleptic syndrome is characterized by muscular rigidity,
tremors, difficulty swallowing, fever, hypertension, mental status
changes, and diaphoresis. Headache is not a manifestation of malignant
neuroleptic syndrome and would not contribute to confirmation of this
diagnosis.
A sexually active young adult is diagnosed with Chlamydia trachomatis
and treated with doxycycline 100 mg BID 7 days. During a follow-up
visit, the patient reports a new onset of right upper quadrant pain and
tenderness on palpation. Alanine aminotransferase (ALT) is 43 U/L, and
aspartate aminotransferase (AST) is 24 U/L. The nurse practitioner
suspects:
A. Jarisch–Herxheimer reaction
pg. 4
