ADVANCED PHARMACOLOGY FINAL
EXAM QUESTIONS AND ANSWERS 100%
PASS
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy?
- ANS To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANS Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
ANS Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANS Aldosterone
antagonist
Heparin exerts its therapeutic action by what? - ANS Upregulating the activity of one of the
body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an
anaphylactic reaction. - ANS Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - ANS Photo-therapy and topical
corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - ANS Thiazide diuretics
@COPYRIGHT ALL RIGHTS RESERVED PAGE 1 OF 10
, What is the effect of cardiac glycosides? - ANS Digitalis glycosides have a negative
chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
ANS Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-
receptor sites? - ANS Atenolol (Tenormin)
What type of action does nitrates have on the body? - ANS Reduction in systemic venous
tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with
known coronary artery disease? - ANS 100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANS Depressing phase 4
depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and
re-establish eumetabolic state in a patient with Graves' disease? - ANS Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
insufficiency? - ANS Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart
failure? - ANS Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? -
ANS Methyldopa (Aldomet)
@COPYRIGHT ALL RIGHTS RESERVED PAGE 2 OF 10
EXAM QUESTIONS AND ANSWERS 100%
PASS
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy?
- ANS To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANS Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
ANS Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANS Aldosterone
antagonist
Heparin exerts its therapeutic action by what? - ANS Upregulating the activity of one of the
body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an
anaphylactic reaction. - ANS Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - ANS Photo-therapy and topical
corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - ANS Thiazide diuretics
@COPYRIGHT ALL RIGHTS RESERVED PAGE 1 OF 10
, What is the effect of cardiac glycosides? - ANS Digitalis glycosides have a negative
chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
ANS Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-
receptor sites? - ANS Atenolol (Tenormin)
What type of action does nitrates have on the body? - ANS Reduction in systemic venous
tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with
known coronary artery disease? - ANS 100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANS Depressing phase 4
depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and
re-establish eumetabolic state in a patient with Graves' disease? - ANS Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
insufficiency? - ANS Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart
failure? - ANS Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? -
ANS Methyldopa (Aldomet)
@COPYRIGHT ALL RIGHTS RESERVED PAGE 2 OF 10
