ONS/ ONCC FUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY CERTIFICATION FINAL EXAM ACTUAL
EXAM 2026-2027 COMPLETE REAL QUESTIONS AND
CORRECT DETAILED ANSWERS WITH RATIONALES
(CORRECT VERIFIED SOLUTIONS) A NEW UPDATED
VERSION |GUARANTEED PASS.
Lesson 1: Foundations to Set the Stage
What happens After the threat ( antigen ) is eliminated
-some plasma cells will undergo apoptosis
-Some will go to the Bone Marrow where they will continue to
secrete antibodies sometimes for years. Memory cells are produced
after the initial response and survive for years resulting in a much
faster response to reinfection - ex; vaccination helps this response)
,Cell-Mediated Immunity
Depends upon cytotoxic T cells and helper T cells and their cyokines
-Helper T cells ( ex: CD4)
- Cytotoxic Cells ( ex CD8)
-more effective against antigens within cells ( because the cells need
to be phagocytize by presenting cells and the cytotoxic cells
then recognize the antigen from fragments of the cell on
presenting cells and then destroy it)
Helper T-Cells (CD4+)
-help other T-Cells by secreting chemicals
-Help B Cells to respond
-rapidly divide, in an effort to stay ahead of the antigen division
-some will turn into effector cells, which secrete different kinds of
cytokines
-respond similarly to B-Cells
,Cytotoxic T-Cells (CD8+)
-Directly kill cells for which they are activated to kill
-rapidly divide, become mature cells, and start killing antigens
Cytokines
-Secreted by lymphocytes
-Tasked with eliminating the antigen
-Multifunctional subsances having proinflammatory, anti-
inflammatory, and regulatory functions in the immune system
, Cytokines Include..
-Interferons (IFNs)
-Tumor necrosis factors
-Transforming GFs
-Interleukins (IL -1, -2, -3, -4, -6, -8, -10, and -15)
-These cytokines regulate antibody production and the functions of B
and T cells as well as interact with antigen-presenting cells and
NKCs
Regulatory T cells also known as Suppressor T cells
regulate the immune response to prevent autoimmune reactions and
limit inflammatory responses
What is a Variant?
Variants are errors in the replication of the cells, they can either be
repaired themselves or go through apoptosis. Variants are:
- changes in the nucleotide sequence of genes
-It can occur because of alteration in DNA which cause
translocation, deletion or addition of base chromosomes
IMMUNOTHERAPY CERTIFICATION FINAL EXAM ACTUAL
EXAM 2026-2027 COMPLETE REAL QUESTIONS AND
CORRECT DETAILED ANSWERS WITH RATIONALES
(CORRECT VERIFIED SOLUTIONS) A NEW UPDATED
VERSION |GUARANTEED PASS.
Lesson 1: Foundations to Set the Stage
What happens After the threat ( antigen ) is eliminated
-some plasma cells will undergo apoptosis
-Some will go to the Bone Marrow where they will continue to
secrete antibodies sometimes for years. Memory cells are produced
after the initial response and survive for years resulting in a much
faster response to reinfection - ex; vaccination helps this response)
,Cell-Mediated Immunity
Depends upon cytotoxic T cells and helper T cells and their cyokines
-Helper T cells ( ex: CD4)
- Cytotoxic Cells ( ex CD8)
-more effective against antigens within cells ( because the cells need
to be phagocytize by presenting cells and the cytotoxic cells
then recognize the antigen from fragments of the cell on
presenting cells and then destroy it)
Helper T-Cells (CD4+)
-help other T-Cells by secreting chemicals
-Help B Cells to respond
-rapidly divide, in an effort to stay ahead of the antigen division
-some will turn into effector cells, which secrete different kinds of
cytokines
-respond similarly to B-Cells
,Cytotoxic T-Cells (CD8+)
-Directly kill cells for which they are activated to kill
-rapidly divide, become mature cells, and start killing antigens
Cytokines
-Secreted by lymphocytes
-Tasked with eliminating the antigen
-Multifunctional subsances having proinflammatory, anti-
inflammatory, and regulatory functions in the immune system
, Cytokines Include..
-Interferons (IFNs)
-Tumor necrosis factors
-Transforming GFs
-Interleukins (IL -1, -2, -3, -4, -6, -8, -10, and -15)
-These cytokines regulate antibody production and the functions of B
and T cells as well as interact with antigen-presenting cells and
NKCs
Regulatory T cells also known as Suppressor T cells
regulate the immune response to prevent autoimmune reactions and
limit inflammatory responses
What is a Variant?
Variants are errors in the replication of the cells, they can either be
repaired themselves or go through apoptosis. Variants are:
- changes in the nucleotide sequence of genes
-It can occur because of alteration in DNA which cause
translocation, deletion or addition of base chromosomes
