NR 507 Advanced Pathophysiology Final
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Dermatomes - Answer-area of the skin that is mainly supplied by branches of a
single spinal sensory nerve root. These spinal sensory nerves enter the nerve root
at the spinal cord, and their branches reach to the periphery of the body.
Substance release at the synapse - Answer-Acetylcholine- Excitatory or inhibitory-
alzheimers
Norepi- Excitatory or inhibitory- sleep/wake cycle, SYNS transmission
Dopa- Excitatory (h1 and h2 receptors) and inhibitory (H3 receptors). parkinson
disease
Spondylolysis - Answer-structural defect (degeneration, fracture, or
developmental defect) in the pars interarticularis of the vertebral arch (the joining
of the vertebral body to the posterior structures). The lumbar spine at L5 is
affected most often.
-Heredity
-Other congenital spinal defects
motor and sensory areas of the brain - Answer-Parietal lobe- major area for
somatic sensory input, located along the postcentral gyrus. which is adjacent to
the primary motor area in the precentral gyrus.
,Primary motor area (Brodmann area 4)- located along the precentral gyrus
forming the primary voluntary motor area (homunculus) (little man).
Association fibers provide communication between sensory and motor
Ischemic penumbra - Answer-ischemic but not infarcted (salvageable) tissue. Peri-
infarct tissue.
-no structural damage
Cerebral infarction - Answer-ischemic- white infarct (affected area is pale and soft
6-12 hours after). necrosis appears by 48 to 72 hours.
Infiltration of macrophages and phagocytosis of necrotic tissue. necrosis resolves
around the 2nd week. glial scarring.
excitotoxins - Answer-Toxins (usually amino acids) that overstimulate glutamate
release and cause neuron suicide.
Agnosia - Answer-the inability to recognize familiar objects.
-tactile/spatial-parietal lobe
-Gerstmann syndrome (loss of spatial orientation of fingers, body, sides and #s)- L
angular gyrus (Parieral)
-Object- Temporo-occipital area
-Associated with CVAs
, Subarachnoid hemorrhage - Answer-Bleeding into the subarachnoid space, where
the cerebrospinal fluid circulates.
-ruptured intracranial aneurysm/trauma
-IICP/irritates meningeal tissues/produces inflammation, blood coats nerve roots,
impairs CSF circulation
-compensatory increase in SBP
Meningitis - Answer-Bacterial- Meningococcus and S. pneumococcus bacteria are
most common
Viral- Specific pathogen cannot be found in CSF
Prostate cancer prevention - Answer--Eat a low fat diet
- Slow growing cancer so DRE and PSA testing prevents
BPH and the urinary system - Answer-- Chronic inflammation
-Bladder outflow obstruction
-Urge to pee often
-delay in starting stream
- Decreased force of stream
-Urinary retention/ overflow incontinence (late sign)
Complications: Hematuria, infections, bladder calculi, retention, hydronephrosis,
renal insufficiency
Cause of respiratory Alkalosis - Answer-- fever
Exam | Verified Questions & Answers for
Guaranteed Exam Success
Dermatomes - Answer-area of the skin that is mainly supplied by branches of a
single spinal sensory nerve root. These spinal sensory nerves enter the nerve root
at the spinal cord, and their branches reach to the periphery of the body.
Substance release at the synapse - Answer-Acetylcholine- Excitatory or inhibitory-
alzheimers
Norepi- Excitatory or inhibitory- sleep/wake cycle, SYNS transmission
Dopa- Excitatory (h1 and h2 receptors) and inhibitory (H3 receptors). parkinson
disease
Spondylolysis - Answer-structural defect (degeneration, fracture, or
developmental defect) in the pars interarticularis of the vertebral arch (the joining
of the vertebral body to the posterior structures). The lumbar spine at L5 is
affected most often.
-Heredity
-Other congenital spinal defects
motor and sensory areas of the brain - Answer-Parietal lobe- major area for
somatic sensory input, located along the postcentral gyrus. which is adjacent to
the primary motor area in the precentral gyrus.
,Primary motor area (Brodmann area 4)- located along the precentral gyrus
forming the primary voluntary motor area (homunculus) (little man).
Association fibers provide communication between sensory and motor
Ischemic penumbra - Answer-ischemic but not infarcted (salvageable) tissue. Peri-
infarct tissue.
-no structural damage
Cerebral infarction - Answer-ischemic- white infarct (affected area is pale and soft
6-12 hours after). necrosis appears by 48 to 72 hours.
Infiltration of macrophages and phagocytosis of necrotic tissue. necrosis resolves
around the 2nd week. glial scarring.
excitotoxins - Answer-Toxins (usually amino acids) that overstimulate glutamate
release and cause neuron suicide.
Agnosia - Answer-the inability to recognize familiar objects.
-tactile/spatial-parietal lobe
-Gerstmann syndrome (loss of spatial orientation of fingers, body, sides and #s)- L
angular gyrus (Parieral)
-Object- Temporo-occipital area
-Associated with CVAs
, Subarachnoid hemorrhage - Answer-Bleeding into the subarachnoid space, where
the cerebrospinal fluid circulates.
-ruptured intracranial aneurysm/trauma
-IICP/irritates meningeal tissues/produces inflammation, blood coats nerve roots,
impairs CSF circulation
-compensatory increase in SBP
Meningitis - Answer-Bacterial- Meningococcus and S. pneumococcus bacteria are
most common
Viral- Specific pathogen cannot be found in CSF
Prostate cancer prevention - Answer--Eat a low fat diet
- Slow growing cancer so DRE and PSA testing prevents
BPH and the urinary system - Answer-- Chronic inflammation
-Bladder outflow obstruction
-Urge to pee often
-delay in starting stream
- Decreased force of stream
-Urinary retention/ overflow incontinence (late sign)
Complications: Hematuria, infections, bladder calculi, retention, hydronephrosis,
renal insufficiency
Cause of respiratory Alkalosis - Answer-- fever
