xPsychiatric Mental Health Nurse Practitioner Exam Prep |
x x x x x x x
Verified Questions & Correct Answers | Comprehensive
x x x x x x x
x ANCC PMHNP Certification Study Guide for Guaranteed
x x x x x x
Success
x
THIS EXAM INCLUDES: x x
✔ Comprehensive PMHNP Practice Questions with Verified Correct Answers
x x x x x x x x
✔ Latest 2026–2027 Psychiatric Mental Health Nurse Practitioner Exam Content
x x x x x x x x x
✔ ANCC PMHNP Certification Preparation Materials
x x x x x
✔ DSM-5 Psychiatric Disorders, Diagnosis & Treatment Review
x x x x x x x
✔ Psychopharmacology Medications, Side Effects & Nursing Interventions
x x x x x x x
✔ Therapy Modalities, Counseling Techniques & Therapeutic Communication
x x x x x x x
✔ Psychiatric Assessment, Mental Status Examination & Differential Diagnosis
x x x x x x x x
,Pharmacology & Mood Stabilizers x x x
1. A patient's lithium level is 1.8 mEq/L. What signs and symptoms would the
x x x x x x x x x x x x x
x PMHNP expect to find?
x x x
A. Hyperactivity, insomnia, and weight gain
x x x x x
B. Severe nausea, diarrhea, confusion, and coarse hand tremors
x x x x x x x x
C. Increased appetite, sedation, and bradycardia
x x x x x
D. Hair loss, hepatotoxicity, and rash
x x x x x
Answer: B - Lithium toxicity occurs at levels >1.5 and presents with severe nausea,
x x x x x x x x x x x x x
diarrhea, vomiting, confusion, drowsiness, muscle weakness, coarse hand tremors, and
x x x x x x x x x x
unsteady gait.
x x
2. A 28-year-old female with bipolar disorder is planning to become pregnant. She
x x x x x x x x x x x x
x has been stable on lithium for 3 years. What should the PMHNP discuss with her
x x x x x x x x x x x x x x
x regarding fetal risk? x x
A. Lithium is safe throughout pregnancy
x x x x x
B. Lithium causes spina bifida, especially in the first trimester
x x x x x x x x x
C. Lithium causes Ebstein anomaly, a congenital heart defect, especially in the first
x x x x x x x x x x x x
trimester
x
D. Lithium causes cleft palate and floppy baby syndrome
x x x x x x x x
Answer: C - Lithium is associated with Ebstein anomaly (congenital heart defect),
x x x x x x x x x x x
particularly when taken during the first trimester.
x x x x x x x
3. Before initiating lithium therapy, which baseline laboratory studies are
x x x x x x x x x
x essential?
,A. CBC, CMP, vitamin D, and iron panel
x x x x x x x
B. TSH, creatinine, BUN, HCG (for females 12-51), EKG (for patients 50+), and urinalysis
x x x x x x x x x x x x x
C. Liver function tests only
x x x x
D. TSH and free T4 only
x x x x x
Answer: B - Baseline labs include TSH, creatinine (0.6-1.2), BUN (10-20), HCG for
x x x x x x x x x x x x
childbearing females, EKG for patients 50 and older, and urinalysis to check for protein.
x x x x x x x x x x x x x x
4. A patient on lithium presents with severe nausea, vomiting, diarrhea, confusion,
x x x x x x x x x x x
x and coarse hand tremors. What is the most appropriate intervention?
x x x x x x x x x
A. Increase the lithium dose
x x x x
B. Add benztropine for tremors
x x x x
C. Check lithium level; hold medication and evaluate for toxicity
x x x x x x x x x
D. Prescribe antiemetics and antidiarrheals
x x x x
Answer: C - These symptoms are consistent with lithium toxicity. The PMHNP should
x x x x x x x x x x x x
check the lithium level and hold the medication.
x x x x x x x x
5. A patient with bipolar I disorder is prescribed valproate (Depakote). What is the
x x x x x x x x x x x x x
x therapeutic range? x
A. 0.6-1.2
x
B. 50-125
x
C. 5-15
x
D. 100-150
x
Answer: B - The normal therapeutic level for Depakote (valproate) is 50-125.
x x x x x x x x x x x
, 6. Which of the following is a teratogenic effect associated with valproate
x x x x x x x x x x x
x (Depakote)?
A. Ebstein anomaly
x x
B. Cleft palate
x x
C. Spina bifida (neural tube defect)
x x x x x
D. Floppy baby syndrome
x x x
Answer: C - Valproate (Depakote) is associated with neural tube defects/spina bifida.
x x x x x x x x x x x
7. A patient on valproate reports hair loss and right upper quadrant pain. What
x x x x x x x x x x x x x
x should the PMHNP order?
x x x
A. Serum lithium level
x x x
B. Liver function tests (AST, ALT)
x x x x x
C. Thyroid function tests
x x x
D. Serum glucose and lipid panel
x x x x x
Answer: B - Alopecia and hepatotoxicity (RUQ pain) are adverse effects of Depakote. The
x x x x x x x x x x x x x
PMHNP should order LFTs (AST 5-40, ALT 5-35).
x x x x x x x x
8. A patient on valproate presents with disorientation, lethargy, and respiratory
x x x x x x x x x x
x depression. What is the priority intervention?
x x x x x
A. Increase the valproate dose
x x x x
B. Administer naloxone
x x
C. Discontinue valproate, check level, and order LFTs and ammonia
x x x x x x x x x
D. Add lithium to the regimen
x x x x x