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PHARM 370 Pharmacology Exam 10 – 120+ Exam Questions and Verified Answers on Chemotherapy, Antineoplastic Drugs, Breast Cancer, Monoclonal Antibodies & Cancer Pharmacology

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This comprehensive PHARM 370 Exam 10 pharmacology study guide contains more than 120 updated exam questions and verified answers focused on cancer pharmacology, chemotherapy, antineoplastic agents, targeted cancer therapies, monoclonal antibodies, and breast cancer treatment. The resource provides detailed NCLEX-style review questions covering the cell cycle, DNA replication, mitotic inhibitors, alkylating agents, hormonal cancer therapies, angiogenesis inhibitors, tyrosine kinase inhibitors, chemotherapy adverse effects, and oncology nursing considerations. The document thoroughly reviews essential oncologic pharmacologic principles including cell-cycle specific chemotherapy, S phase and M phase inhibition, monoclonal antibody therapy, selective estrogen receptor modulators (SERMs), tyrosine kinase inhibition, immunomodulation strategies, and targeted cancer treatments. Key medications discussed include rituximab, vinblastine, cyclophosphamide, tamoxifen, fulvestrant, doxorubicin, imatinib, bevacizumab, anastrozole, mesna, and ondansetron. Students will strengthen understanding of antineoplastic drug mechanisms of action, organ-specific toxicities, chemotherapy safety precautions, contraindications, and management of treatment-related complications. The study guide also provides clinically relevant nursing considerations involving myelosuppression, alopecia, nausea and vomiting prevention, hemorrhagic cystitis, cardiotoxicity, neurotoxicity, extravasation injuries, infertility risks, and infection prevention during chemotherapy treatment. Additional topics include bladder toxicity prevention with mesna, severe tissue damage caused by vesicant chemotherapy agents, grapefruit juice interactions with imatinib, and boxed warnings associated with vinblastine administration. Students will also review hormone-sensitive breast cancer therapies including tamoxifen, fulvestrant, and anastrozole for estrogen receptor-positive malignancies. This study material aligns closely with concepts presented in: Lilley, L. L., Rainforth Collins, S., & Snyder, J. S. (2024). Pharmacology and the Nursing Process. Lehne, R. A. (2023). Lehne’s Pharmacology for Nursing Care. Brunton, L. L., Hilal-Dandan, R., & Knollmann, B. C. (2023). Goodman & Gilman’s The Pharmacological Basis of Therapeutics. National Comprehensive Cancer Network (NCCN) guidelines for chemotherapy and targeted cancer therapy. American Cancer Society recommendations for oncology pharmacology and cancer treatment safety. This resource is especially valuable for: Nursing pharmacology students BSN nursing students ADN nursing students Oncology nursing courses Medical-surgical nursing students NCLEX-RN pharmacology preparation Cancer pharmacology review Advanced pharmacology learners Healthcare students studying chemotherapy medications Clinical oncology nursing review courses Keywords: PHARM 370, pharmacology exam 10, cancer pharmacology, chemotherapy drugs, antineoplastic agents, oncology pharmacology, monoclonal antibodies, rituximab, vinblastine, cyclophosphamide, doxorubicin, tamoxifen, fulvestrant, anastrozole, imatinib, bevacizumab, mesna, ondansetron, breast cancer medications, chemotherapy side effects, targeted cancer therapy, tyrosine kinase inhibitors, angiogenesis inhibitors, alkylating agents, mitotic inhibitors, cell cycle pharmacology, myelosuppression, alopecia, neurotoxicity, cardiotoxicity, extravasation, hemorrhagic cystitis, hormone therapy for cancer, SERM medications, oncology nursing, chemotherapy nursing care, NCLEX pharmacology review, nursing pharmacology study guide,

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Pharm Exam 11 2026 Exam
Questions and Answers |
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Adenosine is an emergency drug used for paroxysmal supraventricular

tachycardia


(SVTs). It is classified as a(n): - ANSWER ✔✔Antiarrhythmic


Dobutamine, indicated for cardiogenic shock, is classified as a(n): -

ANSWER ✔✔Adrenergic agonist


Select the two emergency use medications that have antiarrhythmic

action: - ANSWER ✔✔Lidocaine and verapamil

, After surgery, the emergency use of neostigmine for the reversal of

nondepolarizing neuromuscular blockade is due to its action as a(n): -

ANSWER ✔✔Acetylcholinesterase inhibitor


Naloxone is essential to reverse an overdose due to its action as a(n): -

ANSWER ✔✔Opioid antagonist


Vasopressin fluid resuscitation for hemorrhagic shock relies on its action

as a: - ANSWER ✔✔Antidiuretic hormone analog


The treatment for a client admitted to the emergency department with

metabolic acidosis is: - ANSWER ✔✔Sodium bicarbonate


Describe the mechanism of action of sodium bicarbonate as an

alkalinizing agent: - ANSWER ✔✔Bicarbonate ion neutralizes H+,

raising blood and urinary pH

Select the emergent antiarrhythmic treatment specifically for paroxysmal

supraventricular tachycardia (SVTs) - ANSWER ✔✔Adenosine


Select the pair of adrenergic agonists indicated for cardiogenic shock -

ANSWER ✔✔Dobutamine and epinephrine


In the event of cardiotoxicity in the presence of hyperkalemia,

hypocalcemia, or hypermagnesemia, which agent would be indicated? -

ANSWER ✔✔Calcium chloride

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