WGU D115 FINAL ADVANCED
PATHOPHYSIOLOGY QUESTIONS AND
CORRECT ANSWERS WITH COMPLETE
SOLUTION | NEW UPDATE 2026 | GRADED A+
A patient has had endured several dosage adjustments of his tricyclic
antidepressant, so the provider recommends genetic testing. Which statement
correctly describes the rationale for genetic testing? - ANSWERS The CYP2D6
gene influences metabolism of tricyclic antidepressants and certain other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene
that codes for color blindness in men. Metabolism of 25% of all prescribed drugs,
including tricyclic antidepressants, beta adrenergic receptor blockers, and
neuroleptics, is influenced by variants in a certain gene, requiring genetic testing
to reduce trial-and-error in estimating appropriate drug-dosage levels.
According to the Centers for Disease Control and Prevention, the 10 most costly
chronic conditions include cardiovascular diseases, obesity, asthma, diabetes,
smoking and alcohol related conditions, cancer, Alzheimer's disease, arthritis and
stroke. Which are the top 4 in ranking from most costly to least costly? -
ANSWERS Cardiovascular diseases, Smoking-related conditions, Alcohol-
related conditions, diabetes
A mother brought her child to the doctor for genetic testing. The health care
provider was trying to explain the genetic results of the child. During his
explanation he tell the mother that the child has 2 X chromosomes and a Y
chromosome in each cell. He begins to explain some physical appears the mother
might notice on her son. He explains that she might notice that he has sparse
, body hair, long limbs and small testes. The health care practitioner is explaining
which syndrome to the mother. - ANSWERS Klinefelter syndrome
Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y
chromosome in each cell. Because of the Y chromosome these individuals have a
male appearance, but they are usually sterile and about half develop female-like
breasts.
A patient reports a maternal family history of Lynch syndrome. Which laboratory
finding might indicate a need for further testing for the presence of Lynch
syndrome in this patient? - ANSWERS Positive heme-occult test
Positive heme-occult because Lynch syndrome is a hereditary form of colorectal
cancer and colorectal bleeding can be a sign of cancer
An individual's acquired immunity is dependent on the function of which cells?
(Select all that apply.) - ANSWERS B lymphocytes
T lymphocytes
Macrophages
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in
acquired immunity.
A 17-year-old female comes to the clinic for a physical exam. As part of the visit,
the APRN considers her risk factors for type 2 diabetes mellitus (T2DM). Risk
factors for T2DM would likely include all of the following except: - ANSWERS
Family history of type 1 diabetes mellitus (T1DM)Type 1 diabetes has the genetic
link and is something they are born with
PATHOPHYSIOLOGY QUESTIONS AND
CORRECT ANSWERS WITH COMPLETE
SOLUTION | NEW UPDATE 2026 | GRADED A+
A patient has had endured several dosage adjustments of his tricyclic
antidepressant, so the provider recommends genetic testing. Which statement
correctly describes the rationale for genetic testing? - ANSWERS The CYP2D6
gene influences metabolism of tricyclic antidepressants and certain other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene
that codes for color blindness in men. Metabolism of 25% of all prescribed drugs,
including tricyclic antidepressants, beta adrenergic receptor blockers, and
neuroleptics, is influenced by variants in a certain gene, requiring genetic testing
to reduce trial-and-error in estimating appropriate drug-dosage levels.
According to the Centers for Disease Control and Prevention, the 10 most costly
chronic conditions include cardiovascular diseases, obesity, asthma, diabetes,
smoking and alcohol related conditions, cancer, Alzheimer's disease, arthritis and
stroke. Which are the top 4 in ranking from most costly to least costly? -
ANSWERS Cardiovascular diseases, Smoking-related conditions, Alcohol-
related conditions, diabetes
A mother brought her child to the doctor for genetic testing. The health care
provider was trying to explain the genetic results of the child. During his
explanation he tell the mother that the child has 2 X chromosomes and a Y
chromosome in each cell. He begins to explain some physical appears the mother
might notice on her son. He explains that she might notice that he has sparse
, body hair, long limbs and small testes. The health care practitioner is explaining
which syndrome to the mother. - ANSWERS Klinefelter syndrome
Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y
chromosome in each cell. Because of the Y chromosome these individuals have a
male appearance, but they are usually sterile and about half develop female-like
breasts.
A patient reports a maternal family history of Lynch syndrome. Which laboratory
finding might indicate a need for further testing for the presence of Lynch
syndrome in this patient? - ANSWERS Positive heme-occult test
Positive heme-occult because Lynch syndrome is a hereditary form of colorectal
cancer and colorectal bleeding can be a sign of cancer
An individual's acquired immunity is dependent on the function of which cells?
(Select all that apply.) - ANSWERS B lymphocytes
T lymphocytes
Macrophages
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in
acquired immunity.
A 17-year-old female comes to the clinic for a physical exam. As part of the visit,
the APRN considers her risk factors for type 2 diabetes mellitus (T2DM). Risk
factors for T2DM would likely include all of the following except: - ANSWERS
Family history of type 1 diabetes mellitus (T1DM)Type 1 diabetes has the genetic
link and is something they are born with
