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This type of medication reduces nasal congestion by
activating alpha1 receptors on nasal blood vessels
which causes vasoconstriction which in turn causes
shrinkage of the swollen membrane followed by
nasal drainage - ✔✔ANSWER ✔✔-
Sympathomimetics (Sudafed)
What does sympathomimetics affect? - ✔✔ANSWER
✔✔-Beta1 and beta2 (increase heart rate and BP)
,What are 4 adverse effects of sympathomimetics? -
✔✔ANSWER ✔✔-1. Rebound congestion
2. CNS stimulation
3. Cardiovascular effects and stroke
4. Abuse potential
What're antihistamines for? (Benadryl) - ✔✔ANSWER
✔✔-Allergic rhinitis
What happens when histamine is released? -
✔✔ANSWER ✔✔-It dilates small blood vessels and
increase capillary permeability
What doesn't antihistamines reduce? - ✔✔ANSWER
✔✔-Nasal congestion
Antihistamines are most effective when? -
✔✔ANSWER ✔✔--Taken regularly
,-Take even when symptoms are absent
Second generation antihistamine is known as what?
What AE does it not cause? - ✔✔ANSWER ✔✔--
Zyrtec
-Sedation
Antihistamines: Adverse Effects - ✔✔ANSWER ✔✔-
Anticholinergic (drying) effects, most common
Dry mouth
Difficulty urinating
Constipation
Changes in vision
Drowsiness
Mild drowsiness to deep sleep
Intranasal antihistamines are indicated for what in
adults and children 12yo and older? - ✔✔ANSWER
✔✔-Allergic rhinits
, AE of intranasal antihistamines (azelastine and
olopatadin) - ✔✔ANSWER ✔✔--Nose bleeds
-Anticholinergic effects
-Unpleasant taste
-Sedation
Opioid antitussives include: - ✔✔ANSWER ✔✔--
codeine and hydrocodone
Non-opioid antitussives include: - ✔✔ANSWER ✔✔--
dextromethorphan
-diphenhydramine
-benzonatate
What is the most common use of cough
medications? - ✔✔ANSWER ✔✔-For the suppression
of a non-productive cough associated with the
common cold and other upper respiratory infections