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Manifestations need prompt evaluation and treatment: -
ANSWER-changes in behavior, fever, cough, pain
how is cholinesterase used in AD? - ANSWER-
Cholinesterase breaks down acetylcholine >
Inhibitor stops break down of acetylcholine; helps to
maintain memory in pt
Cholinesterase inhibitors include: - ANSWER-•donepezil
(Aricept), rivastigmine (Exelon), and galantamine
(Razadyne)
,what are contraindications of cholinesterase agonists? -
ANSWER-•GI bleeding and jaundice; use with caution in
asthma, bradycardia, asthma, hyperthryoidism
what are adverse effects of cholinesterase agonists? -
ANSWER-•MS: muscle cramps, arthritis, bone fractures
•CNS: syncope, insomnia, headache, dizziness
•GI/GU: nausea, vomiting, diarrhea, darkened urine
•Other: hot flashes, increased libido, dehydration
what does memantine do? - ANSWER-protects nerve cells
against excess amounts of glutamate
,what is glutamate? - ANSWER-most abundant
neurotransmitter; released by cells that are damaged from
AD
what meds are often used when treating AD associated
depression? - ANSWER-SSRIs (prozac, zoloft)
what are goals for patients with AD? - ANSWER-1.
Functions at highest level of cognitive ability.
2. Performs basic personal care activities of daily living
including
-Bathing, dressing, feeding, and toileting by self or with
assistance as needed.
3. Experiences no injury.
, 4. Remains in restricted area during ambulation and
activity.
what are the 3 most common cognitive problems in
adults? (wk 15- delirium) - ANSWER-1.Delirium (acute
confusion)
2.Dementia
3.Depression
what is delirium? - ANSWER-**State of temporary but
acute mental confusion
-Common problem
-Life-threatening
-Possibly preventable syndrome