Test Bank for Lippincott Illustrated
Reviews: Pharmacology 8th Edition
by Karen Whalen
1. A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is critical
to prescribing because:
1. Distribution of drugs to target tissue may be affected.
2. The solubility of the drug will not match the site of absorption.
3. There will be less free drug available to generate an effect.
4. Drugs bound to albumin are readily excreted by the kidneys. - answer-1. Distribution of drugs
to target tissue may be affected.
2. Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired action
4. Are converted by the liver to more active and fat-soluble forms - answer-3. Are rapidly
metabolized by the liver and may have little if any desired action
3. The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
1
, 4. Skin - answer-2. Lungs
4. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues - answer-3. Increase the length of time a drug is
available and active
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects - answer-2. Biological half-life
6. Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues - answer-1. Rapidly achieves
drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
2
Reviews: Pharmacology 8th Edition
by Karen Whalen
1. A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is critical
to prescribing because:
1. Distribution of drugs to target tissue may be affected.
2. The solubility of the drug will not match the site of absorption.
3. There will be less free drug available to generate an effect.
4. Drugs bound to albumin are readily excreted by the kidneys. - answer-1. Distribution of drugs
to target tissue may be affected.
2. Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired action
4. Are converted by the liver to more active and fat-soluble forms - answer-3. Are rapidly
metabolized by the liver and may have little if any desired action
3. The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
1
, 4. Skin - answer-2. Lungs
4. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues - answer-3. Increase the length of time a drug is
available and active
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects - answer-2. Biological half-life
6. Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of
the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues - answer-1. Rapidly achieves
drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
2
