MSN 671 NEI Global Video UPDATED ACTUAL
QUESTIONS AND CORRECT Answers
Communication between human CNS neurons at Chemical
synapses is:
An example of volume neurotransmission is: Dopamine in the prefrontal cortex
The direct role of transcription factors is to: Influence gene expression
The term epigenetics refers to: A process determining whether a given gene is expressed or silenced
Presynaptic reuptake transporters are a major method of Serotonin and GABA
inactivation for which of the following?
What is constitutive activity? Signal transduction when no agonist or inverse agonist is bound to the receptor.
A partial agonist has what effect on neurotransmission? Net agonism when neurotransmission is deficient.
Net antagonism when neurotransmission is excessive.
Both of the above answers are correct
Agonists cause ligand-gated ion channels to: Open more frequently
Which of the following is true? Both positive and negative allosteric modulations are possible only in the
presence of a neurotransmitter
, When voltage-sensitive sodium channels are open and Into the neuron
activated, the flow of sodium is:
Which of the following are involved in regulating Both of these which are voltage-sensitive sodium channels and voltage-sensitive
neurotransmission via excitation-secretion coupling? calcium channels.
A 21-year-old man who has just been diagnosed with Impaired cognitive functioning premorbidly with further decline during the
schizophrenia presents with his parents. He speaks with a prodromal phase.
reserved and simple language processing style; he is
able to understand and relate to simple questions but
seems to get lost when the pace of the conversation
between the clinician and parents accelerates. when
reviewing the patient's history, what pattern of cognitive
functioning prior to psychosis onset would you be most
likely to find?
Dopamine (DA) receptors can be categorized as D1 like D1-like receptors are excitatory and D2-like receptors are inhibitory.
(D1 and D5 receptors) and D2 like (D2, D3, and D4
receptors). What differentiates the two groups of
receptors?
Symptoms of schizophrenia are hypothetically Mesocortical and mesolimbic pathways
attributable to malfucntioning in the:
For which set of disorders is psychosis considered an Bipolar mania, Parkinson's disease.
associated feature rather than a defining feature for
diagnosis?
The activation of N-methyl-d-aspartate (NMDA) Glutamate and glycine.
receptors requires the presence of:
A leading hypothesis of psychosis is: Hypofunctioning NMDA receptors.
Dysfunction of NMDA-receptor containing synapses is Excessive DA release in the NA and reduced DA release in the PFC.
hypothesized to lead to excessive glutamate release in
the ventral tegmental area. Downstream, this is
hypothesized to lead to what effects on dopamine (DA)?
The neurodevelopmental hypothesis of schizophrenia Rarely used synapses are pruned, while frequently used synapses are preserved.
centers heavily around the idea that aberrant competitive
elimination occurs. Competitive elimination is a stage of
neurodevelopment in which:
What three neurotransmitter systems are implicated in the Serotonin, glutamate, dopamine
neuropathology of psychosis?
What receptor subtypes act as presynaptic autoreceptors 5HT1A and 5HT1B/D receptors
to inhibit serotonin release?
QUESTIONS AND CORRECT Answers
Communication between human CNS neurons at Chemical
synapses is:
An example of volume neurotransmission is: Dopamine in the prefrontal cortex
The direct role of transcription factors is to: Influence gene expression
The term epigenetics refers to: A process determining whether a given gene is expressed or silenced
Presynaptic reuptake transporters are a major method of Serotonin and GABA
inactivation for which of the following?
What is constitutive activity? Signal transduction when no agonist or inverse agonist is bound to the receptor.
A partial agonist has what effect on neurotransmission? Net agonism when neurotransmission is deficient.
Net antagonism when neurotransmission is excessive.
Both of the above answers are correct
Agonists cause ligand-gated ion channels to: Open more frequently
Which of the following is true? Both positive and negative allosteric modulations are possible only in the
presence of a neurotransmitter
, When voltage-sensitive sodium channels are open and Into the neuron
activated, the flow of sodium is:
Which of the following are involved in regulating Both of these which are voltage-sensitive sodium channels and voltage-sensitive
neurotransmission via excitation-secretion coupling? calcium channels.
A 21-year-old man who has just been diagnosed with Impaired cognitive functioning premorbidly with further decline during the
schizophrenia presents with his parents. He speaks with a prodromal phase.
reserved and simple language processing style; he is
able to understand and relate to simple questions but
seems to get lost when the pace of the conversation
between the clinician and parents accelerates. when
reviewing the patient's history, what pattern of cognitive
functioning prior to psychosis onset would you be most
likely to find?
Dopamine (DA) receptors can be categorized as D1 like D1-like receptors are excitatory and D2-like receptors are inhibitory.
(D1 and D5 receptors) and D2 like (D2, D3, and D4
receptors). What differentiates the two groups of
receptors?
Symptoms of schizophrenia are hypothetically Mesocortical and mesolimbic pathways
attributable to malfucntioning in the:
For which set of disorders is psychosis considered an Bipolar mania, Parkinson's disease.
associated feature rather than a defining feature for
diagnosis?
The activation of N-methyl-d-aspartate (NMDA) Glutamate and glycine.
receptors requires the presence of:
A leading hypothesis of psychosis is: Hypofunctioning NMDA receptors.
Dysfunction of NMDA-receptor containing synapses is Excessive DA release in the NA and reduced DA release in the PFC.
hypothesized to lead to excessive glutamate release in
the ventral tegmental area. Downstream, this is
hypothesized to lead to what effects on dopamine (DA)?
The neurodevelopmental hypothesis of schizophrenia Rarely used synapses are pruned, while frequently used synapses are preserved.
centers heavily around the idea that aberrant competitive
elimination occurs. Competitive elimination is a stage of
neurodevelopment in which:
What three neurotransmitter systems are implicated in the Serotonin, glutamate, dopamine
neuropathology of psychosis?
What receptor subtypes act as presynaptic autoreceptors 5HT1A and 5HT1B/D receptors
to inhibit serotonin release?
