1. Osteoporosis- ANSWER -Progressive loss of bone mass. Increased risk for
fractures. Type 1 occurs primarily in post menopausal women. Type 2 is men and
women. Can be caused by other diseases or medications. Such as oasis, steroids,
heparin, etc.
2. osteomalacia- ANSWER -Softening of the bone. Adults version of rickets.
Low vitamin D. Can also be caused by hyperparathryoidism. Nirmal vitamin d
level is 20-80.
3. Paget Disease- ANSWER -Disorder of bone remodeling. Typically occurs in
one or more bones. They tend to have a high alkaline phosphate level.
4. Treatment for Paget's Disease- ANSWER -Zoledronic acid. Given once a
year via IV infu- sion. Also prescribed a high dose biphosphonate and calcitonin.
5. Treatment for osteomalacia- ANSWER -vitamin D and calcium. Give calcitriol
is vitamin d level is less than 10
6. Bisphosphonates- ANSWER --dronate given for treatment of osteoporosis,
pagets, and osteomalacia
7. Fosamax (alendronate)- ANSWER -Classification- ANSWER -Bone
resorption inhibitor. Bisphos- phonate
Therapeutic Effects- ANSWER -TX and prevention of post-menopausal and
cortico-steroid-in- duced osteoporosis,
Adverse Reactions & side effects- ANSWER -Altered taste, photosensitivity, rash,
muscu- loskeletal pain, fluid overload, esophagitis. Common upset stomach &
heartburn, GI effects
Nursing Implications & teaching:Take first thing in the AM, before eating anything;
then pt MUST remain upright for at least 30 mins! Take only with plain water. Monitor
for GI side effects. Use sunscreen to prevent photosensitivity reactions. Do not give
to those with Renal insufficiency
8. Raloxifene (Evista)- ANSWER -Selective Estrogen Receptor Modulator (SERM)
Osteoporo- sis. Give daily. For those that are intolerant to bisphosphonates. Can
cause hot flashes. Don't give to those with a history of DVT, stroke, MI. Can lower
LDL. Has estrogen side effects. Do not give if at a high risk for uterine or breast
cancer.
9. Duavee (conjugated estrogens/bazedoxifene)- ANSWER -First drug to
combine estrogen with an estrogen agonist/antagonist (bazedoxifene)
Drug should be used for the shortest duration possible. Do not give to patient is they
have a uterus or previous DVT, stroke, MI, PE.
10. Calcitonin (Miacalcin)- ANSWER -nasal spray to decrease bone loss from
osteoporosis; instruct pt. to alternate nostrils each day when administering the
nasal spray to decrease rhinitis. Can cause nose bleeds. Does not affect
osteoporosis of the hip.
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, Nurs 5334 exam 1 ear/eye/urology/bone Questions and Answers
11. Teriparatide (Forteo)- ANSWER -Given for osteoporosis. Only drug that will
build bone by stimulating osteoblast (building of bone). Given subQ for up to two
years. No longer than two years. After two years give a bisphonphosate.
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