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1. Pharmacologic Treatment of Bipolar Disorder - ANSWER Lithium
Anticonvulsants
Second generation antipsychotics
2. SSRI's - ANSWER Mechanism of action
• inhibit 5-HT reuptake
Adverse effects
-diarrhea
-headache
-weight gain
-sexual side effects
3. SNRI's - ANSWER Mechanism of action
• inhibit 5-HT reuptake
• inhibit NE reuptake (increase energy, focus)
• increase DA in prefrontal cortex (increase cognition)
Adverse effects
-elevated blood pressure
-anxiety
-insomnia
-constipation
,4. NDRI's - ANSWER Mechanism of action
• inhibit DA reuptake (increase alertness, motivation)
• inhibit NE reuptake (increase energy)
Adverse effects
-agitation
-headache
-dry mouth
-constipation
-weight loss
5. SSRI Prescribing Pearls: med with mild antihistamine effects - ANSWER
citalopram (Celexa)
6. SSRI Prescribing Pearls: med with no known drug interactions - ANSWER
escitalopram (Lexapro)
7. SSRI Prescribing Pearls: med with longest half-life - ANSWER fluoxetine
(Prozac)
8. SSRI Prescribing Pearls: med that also treats social anxiety and insomnia -
ANSWER paroxetine (Paxil)
9. SSRI Prescribing Pearls: med that treats anxious depression; smokers require
an increased dose - ANSWER fluvoxamine (Luvox)
10.SSRI Prescribing Pearls: med that also treats social anxiety and
hypersomnolence - ANSWER sertraline (Zoloft)
,11.venlafaxine (Effexor) - ANSWER INDICATION
-Depression
-GAD
-Social anxiety disorder
-Panic disorder
12.Unipolar depression - ANSWER major depressive disorder (MDD)
one of the most common mental disorders
-Approximately 7.1% of adults in the U.S. had episode in last year, prevalence
highest (13.1%) among individuals aged 18-25
S/S
-depressed mood
-loss of interest or pleasure in daily activities
-irritability
-withdrawal
-problems with sleep, eating, energy, concentration, or self-worth
-severe depression: may experience thoughts of suicide or psychotic symptoms.
13.Bipolar disorder (BD) - ANSWER Chronic condition characterized by
extreme fluctuations in mood, energy, and ability to function
-Moods may be manic, hypomanic, or depressed and may include mixed mood
or psychotic features
-many have only experienced only one manic episode in their lifetime
-Mood fluctuations may be separated by periods of high stability or may cycle
rapidly
, -diagnosed when a client has one or more episodes of mania or hypomania with
a history of one or more major depressive episodes
-high risk for suicide
14.mania - ANSWER characterized by a persistently elevated, expansive, or
irritable mood. Related symptoms may include inflated self-esteem,
increased goal-directed activity or energy, including grandiosity, decreased
need for sleep, excessive talkativeness, racing thoughts, flight of ideas
(FOI), distractibility, psychomotor agitation, and a propensity to be involved
in high-risk activities. Mania leads to significant functional impairment and
may include psychotic features or necessitate hospitalization
15.Bipolar Type I: - ANSWER requires at least one episode of mania for at
least one week (or any duration if hospitalization due to symptoms is
required)
16.Bipolar Type II: - ANSWER diagnosis requires a current or past hypomanic
episode and a current or past major depressive episode. Symptoms last for at
least 4 days but fewer than seven.
-Hypomanic symptoms are not of sufficient duration or severity to cause
significant functional impairment, psychosis, or hospitalization.
-Anger and irritability are common.
-Clients often enjoy the elevation of mood and are reluctant to report these
symptoms, making bipolar more difficult to diagnose if the client presents in the
depression phase.
17.Cyclothymia: - ANSWER involves the chronic presentation of hypomanic
and depressive symptoms that do not meet the diagnostic criteria for a major
depressive or manic/hypomanic episode.