NSG 322 Exam 1 Drugs Questions With Complete Solutions
What are the side effects of Mirtazapine?
Sedation, appetite stimulation, weight gain
* Less Insomnia, Nausea, and sexual dysfunction effects
What class is Esketamine?
N-methyl-D-Asparate receptor antagonist
What are the uses for Esketamine?
Treatment resistant depression
- Off labe lfor acute suicidality
What is the action of Esketamine?
BLocks glutamate from binding to NMDA receptors = surge in
neurotransmission that appears to relieve depressive symptoms
What are side effects of Esketamine?
Dissociaiton
Elevated BP
Dizziness, sedation, vertigo, numbness, anxiety, and feeling
drunk
Urgency, dysuria
What are patient teachings for Esketamine?
Not eat 2 hours and dirnk 30 minutes prior to Tx d/t N/V
Assess BP prior to giving
Monitor patients for at least 2 hours
don't engage in hazardous activities
, How is eskatmine given?
IN outpatient programs by IV infusion or nasal spray
What is Brexanolone?
Neuroactive Steroid
What is Brexanolone used for?
1st approved drug for postpartum depression
- some abuse potential
What is Brexanolone's action?
Influences GABA-A receptors
Benefit of Brexanolone?
Provides rapid resolution of depressive symptoms of postpartum
depression
Side Effects of Brexanolone
Hypoxia - Monitor pulse ox during tx
Potential for excessive sedation and sudden LOC - continuously
monitor when interacting w/ infant or children during infusion
Dry mouth, flushing, hot flashes
What is the second line of treatment for depression?
Tricyclic Antidepressants
Drugs that are TCAs?
Amitriptyline, doxepin, imipramine, nortriptyline
What is the action of TCAs?
What are the side effects of Mirtazapine?
Sedation, appetite stimulation, weight gain
* Less Insomnia, Nausea, and sexual dysfunction effects
What class is Esketamine?
N-methyl-D-Asparate receptor antagonist
What are the uses for Esketamine?
Treatment resistant depression
- Off labe lfor acute suicidality
What is the action of Esketamine?
BLocks glutamate from binding to NMDA receptors = surge in
neurotransmission that appears to relieve depressive symptoms
What are side effects of Esketamine?
Dissociaiton
Elevated BP
Dizziness, sedation, vertigo, numbness, anxiety, and feeling
drunk
Urgency, dysuria
What are patient teachings for Esketamine?
Not eat 2 hours and dirnk 30 minutes prior to Tx d/t N/V
Assess BP prior to giving
Monitor patients for at least 2 hours
don't engage in hazardous activities
, How is eskatmine given?
IN outpatient programs by IV infusion or nasal spray
What is Brexanolone?
Neuroactive Steroid
What is Brexanolone used for?
1st approved drug for postpartum depression
- some abuse potential
What is Brexanolone's action?
Influences GABA-A receptors
Benefit of Brexanolone?
Provides rapid resolution of depressive symptoms of postpartum
depression
Side Effects of Brexanolone
Hypoxia - Monitor pulse ox during tx
Potential for excessive sedation and sudden LOC - continuously
monitor when interacting w/ infant or children during infusion
Dry mouth, flushing, hot flashes
What is the second line of treatment for depression?
Tricyclic Antidepressants
Drugs that are TCAs?
Amitriptyline, doxepin, imipramine, nortriptyline
What is the action of TCAs?
