NR 565 Advanced Pharmacology
2026 NR 565 Advanced Pharmacology
Practice Exam Expert solved Questions and
Answers with Rationales
1. A patient taking spironolactone is at highest risk for
which electrolyte imbalance?
A. Hypokalemia
B. Hyperkalemia
C. Hypocalcemia
D. Hypernatremia
Answer: B
Rationale: Spironolactone is potassium-sparing → increases serum potassium.
2. Which drug should NOT be given with nitrates due to risk
of severe hypotension?
A. Metformin
B. Sildenafil
C. Atorvastatin
D. Digoxin
Answer: B
Rationale: PDE-5 inhibitors + nitrates → profound vasodilation → hypotension.
3. A patient on warfarin has a new prescription for TMP-
SMX. What is the concern?
A. Decreased INR
B. Increased bleeding risk
C. Hyperglycemia
D. Reduced absorption
Answer: B
Rationale: TMP-SMX increases warfarin effect → elevated INR.
, NR 565 Advanced Pharmacology
4. The antidote for acetaminophen overdose is:
A. Naloxone
B. N-acetylcysteine
C. Flumazenil
D. Vitamin K
Answer: B
Rationale: Restores glutathione and prevents liver damage.
5. Which insulin is appropriate for IV use in DKA?
A. Glargine
B. Lispro
C. Regular insulin
D. NPH
Answer: C
Rationale: Only regular insulin is used IV.
6. ACE inhibitors are contraindicated in:
A. Diabetes
B. Pregnancy
C. Hypertension
D. Heart failure
Answer: B
Rationale: Fetal toxicity (renal damage).
7. A patient taking lithium should monitor:
A. Liver enzymes
B. Serum sodium
C. Thyroid function
D. WBC count
2026 NR 565 Advanced Pharmacology
Practice Exam Expert solved Questions and
Answers with Rationales
1. A patient taking spironolactone is at highest risk for
which electrolyte imbalance?
A. Hypokalemia
B. Hyperkalemia
C. Hypocalcemia
D. Hypernatremia
Answer: B
Rationale: Spironolactone is potassium-sparing → increases serum potassium.
2. Which drug should NOT be given with nitrates due to risk
of severe hypotension?
A. Metformin
B. Sildenafil
C. Atorvastatin
D. Digoxin
Answer: B
Rationale: PDE-5 inhibitors + nitrates → profound vasodilation → hypotension.
3. A patient on warfarin has a new prescription for TMP-
SMX. What is the concern?
A. Decreased INR
B. Increased bleeding risk
C. Hyperglycemia
D. Reduced absorption
Answer: B
Rationale: TMP-SMX increases warfarin effect → elevated INR.
, NR 565 Advanced Pharmacology
4. The antidote for acetaminophen overdose is:
A. Naloxone
B. N-acetylcysteine
C. Flumazenil
D. Vitamin K
Answer: B
Rationale: Restores glutathione and prevents liver damage.
5. Which insulin is appropriate for IV use in DKA?
A. Glargine
B. Lispro
C. Regular insulin
D. NPH
Answer: C
Rationale: Only regular insulin is used IV.
6. ACE inhibitors are contraindicated in:
A. Diabetes
B. Pregnancy
C. Hypertension
D. Heart failure
Answer: B
Rationale: Fetal toxicity (renal damage).
7. A patient taking lithium should monitor:
A. Liver enzymes
B. Serum sodium
C. Thyroid function
D. WBC count
