Page 1 of 26
01 June 2026
PNM300 TEST 2 PREP 2026 WITH 200 REAL EXAM
PRACTICE QUESTIONS AND CORRECT ANSWERS (100%
CORRECT) PNM 300 EXAM 2 LATEST 2026/27 PREP (NEW!)
Which drug may be used early in the treatment of Parkinson's disease but eventually loses
effectiveness and must be replaced by another drug?
A. Amantadine (Symmetrel)
B. Levodopa (Larodopa)
C. Selegiline (Eldepryl)
D. Tolcapone (Tasmar)
A
Which drug may be used as monotherapy or in conjunction with levodopa to treat Parkinson's
disease?
A. Bromocriptine (Parlodel)
B. Benztropine (Cogentin)
C. Carbidopa (Lodosyn)
D. Selegiline (Eldepryl)
D
A patient who is newly diagnosed with Parkinson's disease and beginning medication therapy with
entacapone (Comtan), a COMT inhibitor, asks the nurse, "How soon will improvement occur?"
What is the nurse's best response?
A. "That varies from patient to patient"
B. "You should discuss that with your physician"
C. "You should notice a difference in a few days"
D. "It may take several weeks before you notice any degree of improvement"
C
A patient asks the nurse why a second drug is given with his drugs for Parkinson's disease. The
nurse notes that this drug, an anticholinergic, is given to control or minimize which symptoms?
(Select all that apply)
A. Drooling
B. Constipation
C. Muscle rigidity
D. Bradykinesia
E. Dry mouth
A, C
The expected side effects of the anticholinergic drugs used to treat Parkinson's disease include
(Select all that apply)
A. dry mouth and decreased salivation
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01 June 2026
B. urinary retention
C. decreased GI motility and constipation
D. pupillary constriction
E. smooth muscle relaxation
A, B, C, E
Carbidopa-levodopa (Sinemet) is prescribed for a patient with Parkinson's disease. The nurse will
inform the patient of which possible adverse effects? (Select all that apply)
A. Palpitations
B. Insomnia
C. Hypotension
D. Urinary frequency
E. GI distress
A, C, E
Which statement describes the rationale for combining carbidopa with levodopa in the treatment
of Parkinson's disease?
A. The combination eliminates the side effects of both medications
B. The combination decrease the liver's first-pass effect on dopamine
C. The combination decreases the level of acetylcholine at the synapses
D. The combination allows lower levels of dopamine to be used with the same effect on alleviation
of symptoms
D
A patient is taking entacapone (Comtan) as part of the therapy for Parkinson'd disease. Which
intervention by the nurse is appropriate at this time?
A. Notify the patient that this drug causes discoloration of the urine
B Limit the patient's intake of tyramine-containing foods
C. Monitor the results of renal studies because this drug can seriously affect renal function
D. Force fluids to prevent dehydration
A
A patient will be taking selegiline (Eldepryl), 10 mg daily, in addition to dopamine replacement
therapy for Parkinson's disease. The nurse will implement which precautions regarding selegiline?
A. Teach the patient to avoid foods containing tyramine
B. Monitor for dizziness
C. Inform the patient that this drug may cause urine discoloration
D. Monitor for weight gain
B
A patient with Parkinson's disease will start taking entacapone (Comtan) along with the
carbidopa-levodopa (Sinemet) he has been taking for a few years. The nurse recognizes that the
advantage of taking entacapone is that
A. the entacapone can reduce on-off effects
B. the levodopa may be stopped in a few days
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01 June 2026
C. there is less GI upset with entacapone
D. it does not cause the cheese effect
A
The nurse is assessing a patient who has begun therapy with amantadine (Symmetrel) for
Parkinson's disease. The nurse will look for which possible adverse effects? (Select all that apply)
A. Nausea
B. Palpitations
C. Dizziness
D. Insomnia
E. Fatigue
A, C, D
When providing teaching to a patient receiving an anticholinergic for the treatment of PD, the
nurse will include which information?
A. Take the medication first thing in the morning.
B. Limit fluid intake when taking this drug.
C. The tremors you experience will be reduced within 24 hours of taking this drug.
D. Do not take this medication at the same time as other medications.
D
Which drug used for the management of the patient with PD is most likely to cause postural
hypotension, including insomnia and nausea?
A. amantadine (Symmetrel)
B. selegiline (Eldepryl)
C. tolcapone (Tasmar)
D. entacapone (Comtan)
A
The "off-on phenomenon" that some patients with PD experience is best explained as the
A. need to take a drug holiday to improve response to medications.
B. variable response to levodopa, resulting in periods of good control and periods of poor control of
PD symptoms.
C. alternating schedule of medications needed to control PD.
D. fluctuation of emotions that often occurs with PD.
B
The nurse reads in the patient's medication history that the patient is taking buspirone (BuSpar).
The nurse interprets that the patient may have which disorder?
A. Anxiety disorder
B. Depression
C. Schizophrenia
D. Bipolar disorder
ANS: A
Before beginning a patient's therapy with selective serotonin reuptake inhibitor (SSRI)
antidepressants, the nurse will assess for concurrent use of which medications or medication
01 June 2026
PNM300 TEST 2 PREP 2026 WITH 200 REAL EXAM
PRACTICE QUESTIONS AND CORRECT ANSWERS (100%
CORRECT) PNM 300 EXAM 2 LATEST 2026/27 PREP (NEW!)
Which drug may be used early in the treatment of Parkinson's disease but eventually loses
effectiveness and must be replaced by another drug?
A. Amantadine (Symmetrel)
B. Levodopa (Larodopa)
C. Selegiline (Eldepryl)
D. Tolcapone (Tasmar)
A
Which drug may be used as monotherapy or in conjunction with levodopa to treat Parkinson's
disease?
A. Bromocriptine (Parlodel)
B. Benztropine (Cogentin)
C. Carbidopa (Lodosyn)
D. Selegiline (Eldepryl)
D
A patient who is newly diagnosed with Parkinson's disease and beginning medication therapy with
entacapone (Comtan), a COMT inhibitor, asks the nurse, "How soon will improvement occur?"
What is the nurse's best response?
A. "That varies from patient to patient"
B. "You should discuss that with your physician"
C. "You should notice a difference in a few days"
D. "It may take several weeks before you notice any degree of improvement"
C
A patient asks the nurse why a second drug is given with his drugs for Parkinson's disease. The
nurse notes that this drug, an anticholinergic, is given to control or minimize which symptoms?
(Select all that apply)
A. Drooling
B. Constipation
C. Muscle rigidity
D. Bradykinesia
E. Dry mouth
A, C
The expected side effects of the anticholinergic drugs used to treat Parkinson's disease include
(Select all that apply)
A. dry mouth and decreased salivation
, Page 2 of 26
01 June 2026
B. urinary retention
C. decreased GI motility and constipation
D. pupillary constriction
E. smooth muscle relaxation
A, B, C, E
Carbidopa-levodopa (Sinemet) is prescribed for a patient with Parkinson's disease. The nurse will
inform the patient of which possible adverse effects? (Select all that apply)
A. Palpitations
B. Insomnia
C. Hypotension
D. Urinary frequency
E. GI distress
A, C, E
Which statement describes the rationale for combining carbidopa with levodopa in the treatment
of Parkinson's disease?
A. The combination eliminates the side effects of both medications
B. The combination decrease the liver's first-pass effect on dopamine
C. The combination decreases the level of acetylcholine at the synapses
D. The combination allows lower levels of dopamine to be used with the same effect on alleviation
of symptoms
D
A patient is taking entacapone (Comtan) as part of the therapy for Parkinson'd disease. Which
intervention by the nurse is appropriate at this time?
A. Notify the patient that this drug causes discoloration of the urine
B Limit the patient's intake of tyramine-containing foods
C. Monitor the results of renal studies because this drug can seriously affect renal function
D. Force fluids to prevent dehydration
A
A patient will be taking selegiline (Eldepryl), 10 mg daily, in addition to dopamine replacement
therapy for Parkinson's disease. The nurse will implement which precautions regarding selegiline?
A. Teach the patient to avoid foods containing tyramine
B. Monitor for dizziness
C. Inform the patient that this drug may cause urine discoloration
D. Monitor for weight gain
B
A patient with Parkinson's disease will start taking entacapone (Comtan) along with the
carbidopa-levodopa (Sinemet) he has been taking for a few years. The nurse recognizes that the
advantage of taking entacapone is that
A. the entacapone can reduce on-off effects
B. the levodopa may be stopped in a few days
, Page 3 of 26
01 June 2026
C. there is less GI upset with entacapone
D. it does not cause the cheese effect
A
The nurse is assessing a patient who has begun therapy with amantadine (Symmetrel) for
Parkinson's disease. The nurse will look for which possible adverse effects? (Select all that apply)
A. Nausea
B. Palpitations
C. Dizziness
D. Insomnia
E. Fatigue
A, C, D
When providing teaching to a patient receiving an anticholinergic for the treatment of PD, the
nurse will include which information?
A. Take the medication first thing in the morning.
B. Limit fluid intake when taking this drug.
C. The tremors you experience will be reduced within 24 hours of taking this drug.
D. Do not take this medication at the same time as other medications.
D
Which drug used for the management of the patient with PD is most likely to cause postural
hypotension, including insomnia and nausea?
A. amantadine (Symmetrel)
B. selegiline (Eldepryl)
C. tolcapone (Tasmar)
D. entacapone (Comtan)
A
The "off-on phenomenon" that some patients with PD experience is best explained as the
A. need to take a drug holiday to improve response to medications.
B. variable response to levodopa, resulting in periods of good control and periods of poor control of
PD symptoms.
C. alternating schedule of medications needed to control PD.
D. fluctuation of emotions that often occurs with PD.
B
The nurse reads in the patient's medication history that the patient is taking buspirone (BuSpar).
The nurse interprets that the patient may have which disorder?
A. Anxiety disorder
B. Depression
C. Schizophrenia
D. Bipolar disorder
ANS: A
Before beginning a patient's therapy with selective serotonin reuptake inhibitor (SSRI)
antidepressants, the nurse will assess for concurrent use of which medications or medication
