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ANCC FNP BOARD EXAM NEWEST 2026 – FAMILY NURSE PRACTITIONER CERTIFICATION TEST BANK WITH 200 REAL EXAM QUESTIONS AND CORRECT DETAILED ANSWERS (GRADED A+) MOST RECENT

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ANCC FNP Board Exam 2026 – 200+ real questions + verified answers with detailed rationales. Covers health promotion, cardiovascular, respiratory, GI, GU, reproductive, musculoskeletal, neurology, mental health, endocrine, immunology, infectious disease, pharmacology, professional ethics, EBP, and research. Graded A+. Instant download. Pass your Family Nurse Practitioner certification on the first try!

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ANCC FNP BOARD EXAM NEWEST 2026 ACTUAL EXAM
TEST BANK| FAMILY NURSING PRACTITIONER ANCC
BOARD EXAM — 200 Questions

Section 1: Health Promotion and Disease Prevention (Questions 1-17)

1 A 45-year-old patient with a family history of colorectal cancer in a first-degree relative diagnosed at age 50
asks about colorectal cancer screening. According to the US Preventive Services Task Force (USPSTF) 2021
recommendations, which screening strategy is most appropriate?
A) Begin screening at age 40 with colonoscopy every 10 years
B) Begin screening at age 45 with fecal immunochemical test (FIT) annually
C) Begin screening at age 50 with colonoscopy every 5 years
D) Begin screening at age 40 with flexible sigmoidoscopy every 5 years
Answer: B
Rationale: The USPSTF 2021 recommends starting colorectal cancer screening at age 45 for average-risk
individuals. The patient's family history of a first-degree relative diagnosed at age 50 puts them at increased risk,
but not high enough to justify starting before age 45. Option B (FIT annually) is an accepted screening modality.
Option A is too early and uses a longer interval than recommended. Option C starts too late and colonoscopy is
recommended every 10 years, not 5. Option D starts too early.

2 Which of the following combinations of preventive services is most appropriate for a 55-year-old patient with a
30-pack-year smoking history who currently smokes and has well-controlled hypertension?
A) Annual low-dose CT scan for lung cancer, pharmacotherapy for smoking cessation, and aspirin for primary
prevention of cardiovascular disease
B) Annual chest X-ray for lung cancer, nicotine replacement therapy, and blood pressure monitoring every 6
months
C) Low-dose CT scan every 2 years for lung cancer, counseling for smoking cessation, and statin therapy
D) Spirometry annually, varenicline for smoking cessation, and daily aspirin
Answer: A
Rationale: The USPSTF recommends annual low-dose CT for lung cancer screening in adults aged 50-80 with a
20-pack-year history who currently smoke or quit within 15 years. Smoking cessation pharmacotherapy is
first-line. Aspirin is recommended for primary prevention of CVD in adults aged 40-59 with a 10-year risk "e10%
(this patient likely meets criteria due to smoking and hypertension). Option B uses chest X-ray, which is not
recommended. Option C uses CT every 2 years, which is not the recommended interval. Option D includes
spirometry, which is not recommended for screening, and aspirin may be appropriate but not the best combination.

3 A 28-year-old patient is newly diagnosed with prediabetes (HbA1c 6.0%, fasting glucose 108 mg/dL).
According to the American Diabetes Association (ADA) 2024 Standards of Care, which of the following
interventions is most appropriate for diabetes prevention?
A) Initiate metformin therapy and refer to a diabetes self-management education program
B) Refer to an intensive behavioral lifestyle intervention program and consider metformin if BMI "e35 kg/m²
C) Prescribe a low-carbohydrate diet and monitor HbA1c annually
D) Start insulin glargine to achieve normoglycemia and prevent beta-cell decline
Answer: B

,Rationale: The ADA recommends that patients with prediabetes be referred to an intensive lifestyle intervention
program targeting 7% weight loss and 150 minutes of physical activity per week. Metformin is considered for those
with BMI "e35 kg/m², age <60, or history of gestational diabetes. Option B correctly reflects this. Option A
recommends metformin without lifestyle as first-line, which is not standard. Option C lacks the comprehensive
lifestyle program. Option D is inappropriate as insulin is not indicated for prediabetes.

4 A 65-year-old patient with no history of falls, osteoporosis, or fractures is seen for a wellness visit. The patient
has a 10-year fracture risk (FRAX) of 9% for major osteoporotic fracture and 3% for hip fracture. Which of the
following is the most appropriate management according to the USPSTF 2018 recommendations?
A) Screen with dual-energy X-ray absorptiometry (DXA) and start bisphosphonate therapy if T-score "d -2.5
B) Screen with DXA and start bisphosphonate therapy if T-score "d -1.0
C) No screening or treatment; provide calcium and vitamin D supplementation
D) Screen with DXA and start denosumab if T-score "d -2.0
Answer: A
Rationale: The USPSTF recommends screening for osteoporosis with DXA in women aged 65 and older. Treatment
is recommended for those with a T-score "d -2.5 or a history of fragility fracture. The FRAX risk does not alter the
screening recommendation but can inform shared decision-making. Option A is correct. Option B uses a threshold
of -1.0, which is osteopenia and not typically treated. Option C omits screening, which is recommended. Option D
uses denosumab as first-line, but bisphosphonates are first-line for most patients.

5 A 30-year-old patient with no medical history requests a prescription for pre-exposure prophylaxis (PrEP) for
HIV prevention. The patient reports having condomless anal sex with multiple male partners. Which of the
following is the most appropriate initial evaluation and management?
A) Order HIV antigen/antibody test, serum creatinine, and hepatitis B serology; if negative, prescribe tenofovir
disoproxil fumarate/emtricitabine (TDF/FTC) daily
B) Order HIV RNA test and complete blood count; if negative, prescribe tenofovir alafenamide/emtricitabine
(TAF/FTC) on-demand
C) Order HIV antibody test only; if negative, prescribe TDF/FTC daily without additional lab monitoring
D) Order HIV antigen/antibody test and STI screening; if negative, prescribe cabotegravir injections every 2
months

Answer: A
Rationale: The CDC guidelines for PrEP recommend testing for HIV (antigen/antibody), serum creatinine, and
hepatitis B before starting TDF/FTC or TAF/FTC. TDF/FTC is approved for daily oral PrEP in all populations.
Option A is correct. Option B uses an HIV RNA test, which is not the standard screening, and on-demand PrEP is
not recommended for men who have sex with men (MSM) with multiple partners. Option C omits necessary labs.
Option D uses cabotegravir, which is an option but requires injection every 2 months after an initial dose, and is not
the first choice for this patient.

6 A 50-year-old patient with a body mass index (BMI) of 32 kg/m² and a waist circumference of 110 cm is seen
for a preventive visit. The patient has a blood pressure of 128/82 mmHg, fasting glucose 98 mg/dL, and lipid
panel: total cholesterol 200 mg/dL, LDL 130 mg/dL, HDL 40 mg/dL, triglycerides 150 mg/dL. According to the
American Heart Association (AHA) 2019 guidelines, which of the following is the most appropriate initial
intervention for cardiovascular disease prevention?

A) Start moderate-intensity statin therapy because the patient has metabolic syndrome and a 10-year ASCVD
risk that likely exceeds 7.5%
B) Start high-intensity statin therapy because the patient has diabetes and LDL >100 mg/dL
C) Start antihypertensive therapy with a thiazide diuretic to achieve blood pressure <130/80 mmHg
D) Initiate lifestyle modification alone and reassess in 6 months before considering pharmacotherapy

,Answer: A
Rationale: The patient meets criteria for metabolic syndrome (central obesity, elevated BP, low HDL, elevated
triglycerides). The 10-year ASCVD risk should be calculated; given these risk factors, it is likely "e7.5%, which is
the threshold for moderate-intensity statin therapy per AHA guidelines. Option A is correct. Option B is incorrect
because the patient does not have diabetes (fasting glucose <126 mg/dL). Option C is not indicated as BP is
<130/80. Option D would delay necessary pharmacotherapy.

7 A 22-year-old patient who is a college athlete presents for a preparticipation physical evaluation. The patient
reports no symptoms but has a family history of sudden cardiac death in a brother at age 30. Which of the
following screening approaches is most appropriate according to the American Heart Association (AHA) 2024
recommendations?

A) Perform a 12-lead ECG and refer to cardiology if any abnormality is found
B) Obtain a thorough history and physical exam; if normal, no further testing is needed
C) Order an echocardiogram and stress test to rule out hypertrophic cardiomyopathy
D) Refer to cardiology for genetic testing regardless of symptoms
Answer: A
Rationale: The AHA recommends that for athletes with a family history of sudden cardiac death, a 12-lead ECG
should be performed as part of the screening. If the ECG is abnormal, further evaluation is indicated. Option A is
correct. Option B is insufficient given the family history. Option C is overly aggressive as initial screening. Option
D is not indicated without a confirmed diagnosis in the family.

8 A 35-year-old patient with a history of gestational diabetes mellitus (GDM) during pregnancy 5 years ago is
seen for a preventive visit. The patient is not currently pregnant and has a BMI of 28 kg/m². According to the
USPSTF 2021 recommendations, which of the following is the most appropriate screening strategy for type 2
diabetes?

A) Screen for type 2 diabetes with fasting plasma glucose every 3 years
B) Screen for type 2 diabetes with HbA1c annually
C) No screening is necessary because the patient is asymptomatic and under age 40
D) Screen for type 2 diabetes with an oral glucose tolerance test every 2 years
Answer: B
Rationale: The USPSTF recommends screening for type 2 diabetes in adults aged 35-70 who are overweight or
obese. However, patients with a history of GDM are at high risk and should be screened earlier and more
frequently. The ADA recommends screening with HbA1c, fasting glucose, or OGTT at least every 3 years, but
given the history, annual screening is appropriate. Option B is correct. Option A is less frequent than
recommended. Option C is incorrect because screening is indicated. Option D is not the standard initial test.

9 A 60-year-old patient with a 40-pack-year smoking history quit smoking 5 years ago. The patient has no other
risk factors for lung cancer. According to the USPSTF 2021 recommendations, which of the following is the
most appropriate lung cancer screening strategy?
A) Annual low-dose CT scan until age 80
B) Annual low-dose CT scan until age 75
C) No screening because the patient quit more than 15 years ago
D) Annual chest X-ray until age 80
Answer: A
Rationale: The USPSTF recommends annual low-dose CT for lung cancer screening in adults aged 50-80 with a
20-pack-year history who currently smoke or have quit within the past 15 years. This patient quit 5 years ago, so
they are still within the 15-year window. Option A is correct. Option B has the wrong upper age limit. Option C is

, incorrect because the quit time is less than 15 years. Option D uses chest X-ray, which is not recommended.

10 A 70-year-old patient who is a former smoker (quit 20 years ago) is concerned about abdominal aortic
aneurysm (AAA). The patient has no history of hypertension or cardiovascular disease. According to the
USPSTF 2019 recommendations, which of the following is the most appropriate screening strategy?
A) One-time ultrasound screening for AAA
B) No screening is recommended because the patient is over 65
C) Annual ultrasound screening for AAA
D) Screening with CT angiography every 5 years
Answer: B
Rationale: The USPSTF recommends one-time ultrasound screening for AAA in men aged 65-75 who have ever
smoked. This patient is a former smoker but is 70 years old, so they would have been eligible for screening
between ages 65-75. However, the recommendation is for one-time screening. If they have not been screened, it is
appropriate to screen now. But the question asks for the most appropriate strategy. Since the patient is 70 and has
never been screened, one-time screening is recommended. However, option B states 'No screening is recommended
because the patient is over 65' – that is incorrect because the recommendation covers up to age 75. Wait, re-read:
the patient is 70, so within range. But the options: A is one-time ultrasound; B says no screening because over 65
(false); C annual (false); D CT (false). So A is correct. But the explanation: The USPSTF recommends one-time
screening for men 65-75 who have ever smoked. This patient qualifies. So answer is A. However, I need to ensure
the answer is consistent. Let me correct: The correct answer is A. The explanation: The USPSTF recommends
one-time ultrasound screening for AAA in men aged 65-75 with a history of smoking. This patient meets criteria,
so one-time screening is appropriate.

11 A community health initiative aims to reduce the incidence of type 2 diabetes through a multi-level intervention
targeting dietary habits, physical activity, and social support. Which theoretical framework would most
effectively guide the evaluation of this intervention's impact on both individual behavior change and
community-level norms?

A) Health Belief Model
B) Transtheoretical Model
C) Social Cognitive Theory
D) Diffusion of Innovations Theory
Answer: C
Rationale: Social Cognitive Theory (SCT) emphasizes reciprocal determinism among personal, behavioral, and
environmental factors, making it ideal for interventions targeting individual behavior change and community
norms. The Health Belief Model focuses on individual perceptions, the Transtheoretical Model on stages of
change, and Diffusion of Innovations on adoption of new behaviors, but SCT best captures the multi-level
interaction.

12 A 45-year-old patient with a BMI of 32, hypertension, and a family history of colorectal cancer presents for a
preventive health visit. According to the USPSTF, which combination of screenings should be recommended at
this visit?
A) Colorectal cancer screening starting at age 45, blood pressure screening, and diabetes screening for adults
with overweight or obesity
B) Colorectal cancer screening starting at age 50, blood pressure screening, and lipid panel
C) Colorectal cancer screening only, as hypertension is already diagnosed
D) Colorectal cancer screening, diabetes screening for all adults regardless of risk factors, and ECG for
cardiovascular risk

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