Biom 3090 Autonomic pharmacology Exam
Questions With Correct Answers
Going from brain down the spinal cord, what are the 4 regions of spinal
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cord nerves? - CORRECT ANSWER✔✔-Cranial, thoracic, lumbar, sacral
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Which two regions of the spinal cord control the PSNS? - CORRECT
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ANSWER✔✔-Cranial and Sacral | |
Which two regions of the spinal cord control the SNS? - CORRECT
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ANSWER✔✔-Thoracic and Lumbar | |
What is unique about the ganglia of the SNS? - CORRECT ANSWER✔✔-
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Multiple presynaptic fibers synapse onto one single postsynaptic fiber.
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The ganglia is close to the spinal cord.
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What is unique about the ganglia of the PSNS? - CORRECT ANSWER✔✔-
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One pre onto one post synaptic fiber. The pre fiber is long.
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T or F. All postganglionic SNS neurons release NE - CORRECT
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ANSWER✔✔-False. Most do but some do not. The SNS postganglionic | | | | | | | | | |
fibers connected to the sweat gland and adrenal gland secrete Ach.
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,What do the adrenal glands secrete? - CORRECT ANSWER✔✔-
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epinephrine and norepinephrine | |
choline acetyltransferase (ChAT) - CORRECT ANSWER✔✔-Makes
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acetylcholine
Acetylcholinesterase (AchE) - CORRECT ANSWER✔✔-Degrades | | | | |
acetylcholine
How do muscarinic acetylcholine receptors transmit an intracellular
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signal? - CORRECT ANSWER✔✔-G-protein coupled receptors.
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Which M receptors are excitatory? - CORRECT ANSWER✔✔-M1, M3,
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M5
What do the excitatory M receptors do within the cell? - CORRECT
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ANSWER✔✔-Increased IP3 production and increased DAG. | | | | |
What M receptors are inhibitory? - CORRECT ANSWER✔✔-M2, M4
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What do the inhibitory M receptors do within the cell? - CORRECT
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ANSWER✔✔-Decreased cAMP production. | |
, How do nicotinic acetylcholine receptors transmit an intracellular
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signal? - CORRECT ANSWER✔✔-Ion channels
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Which nicotinic receptors are stimulatory and which are inhibitory? -
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CORRECT ANSWER✔✔-Nn and Nm are stimulatory.
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M1 receptors - CORRECT ANSWER✔✔-Present at ganglia but in reality
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their effects are negligible.
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M2 - CORRECT ANSWER✔✔-Heart. Decreased rate / force of
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contraction.
M3 - CORRECT ANSWER✔✔-Contraction of smooth muscle, gland
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secretion (sweat, salivary. Glands are innervated by SNS), Endothelial
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cell release of EDRF, sphincters of the eye.
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M5 - CORRECT ANSWER✔✔-Endothelial cell release of EDGF (AKA Nitric
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|Oxide which reacts with guanylyl cyclase in the smooth muscle which
| | | | | | | | | | |
increases cGMP which relaxes the surrounding smooth muscle which
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relaxes the vessel).
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Questions With Correct Answers
Going from brain down the spinal cord, what are the 4 regions of spinal
| | | | | | | | | | | | | |
cord nerves? - CORRECT ANSWER✔✔-Cranial, thoracic, lumbar, sacral
| | | | | | |
Which two regions of the spinal cord control the PSNS? - CORRECT
| | | | | | | | | | | |
ANSWER✔✔-Cranial and Sacral | |
Which two regions of the spinal cord control the SNS? - CORRECT
| | | | | | | | | | | |
ANSWER✔✔-Thoracic and Lumbar | |
What is unique about the ganglia of the SNS? - CORRECT ANSWER✔✔-
| | | | | | | | | | |
Multiple presynaptic fibers synapse onto one single postsynaptic fiber.
| | | | | | | | |
The ganglia is close to the spinal cord.
| | | | | | |
What is unique about the ganglia of the PSNS? - CORRECT ANSWER✔✔-
| | | | | | | | | | |
One pre onto one post synaptic fiber. The pre fiber is long.
| | | | | | | | | | |
T or F. All postganglionic SNS neurons release NE - CORRECT
| | | | | | | | | | |
ANSWER✔✔-False. Most do but some do not. The SNS postganglionic | | | | | | | | | |
fibers connected to the sweat gland and adrenal gland secrete Ach.
| | | | | | | | | |
,What do the adrenal glands secrete? - CORRECT ANSWER✔✔-
| | | | | | | |
epinephrine and norepinephrine | |
choline acetyltransferase (ChAT) - CORRECT ANSWER✔✔-Makes
| | | | | |
acetylcholine
Acetylcholinesterase (AchE) - CORRECT ANSWER✔✔-Degrades | | | | |
acetylcholine
How do muscarinic acetylcholine receptors transmit an intracellular
| | | | | | | |
signal? - CORRECT ANSWER✔✔-G-protein coupled receptors.
| | | | |
Which M receptors are excitatory? - CORRECT ANSWER✔✔-M1, M3,
| | | | | | | | |
M5
What do the excitatory M receptors do within the cell? - CORRECT
| | | | | | | | | | | |
ANSWER✔✔-Increased IP3 production and increased DAG. | | | | |
What M receptors are inhibitory? - CORRECT ANSWER✔✔-M2, M4
| | | | | | | |
What do the inhibitory M receptors do within the cell? - CORRECT
| | | | | | | | | | | |
ANSWER✔✔-Decreased cAMP production. | |
, How do nicotinic acetylcholine receptors transmit an intracellular
| | | | | | | |
signal? - CORRECT ANSWER✔✔-Ion channels
| | | |
Which nicotinic receptors are stimulatory and which are inhibitory? -
| | | | | | | | | |
CORRECT ANSWER✔✔-Nn and Nm are stimulatory.
| | | | |
M1 receptors - CORRECT ANSWER✔✔-Present at ganglia but in reality
| | | | | | | | | |
their effects are negligible.
| | |
M2 - CORRECT ANSWER✔✔-Heart. Decreased rate / force of
| | | | | | | | |
contraction.
M3 - CORRECT ANSWER✔✔-Contraction of smooth muscle, gland
| | | | | | | |
secretion (sweat, salivary. Glands are innervated by SNS), Endothelial
| | | | | | | | |
cell release of EDRF, sphincters of the eye.
| | | | | | |
M5 - CORRECT ANSWER✔✔-Endothelial cell release of EDGF (AKA Nitric
| | | | | | | | |
|Oxide which reacts with guanylyl cyclase in the smooth muscle which
| | | | | | | | | | |
increases cGMP which relaxes the surrounding smooth muscle which
| | | | | | | | |
relaxes the vessel).
| |
