NR 507 COMPLETE STUDY QUESTIONS
AND ANSWERS
Hypersensitivity: Type 1 - CORRECT ANSWER--Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 - CORRECT ANSWER--Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
Hypersensitivity 2 - CORRECT ANSWER--Graves Disease (hyperthyroidism) -alters
function not destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or
lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 - CORRECT ANSWER--Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released
into the blood or bodily fluids, and the complex is then deposited in the tissues
Hypersensitivity: Type 3 - CORRECT ANSWER--rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) - CORRECT ANSWER-Hypersensitivity Type 1
First responders to innate the immune system - CORRECT ANSWER-Neutrophils
Allergic contact dermatitis - CORRECT ANSWER-Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by: - CORRECT ANSWER--IgG IgM
-macrophages are primary effort cells
, -
Serum Sickness - CORRECT ANSWER-type 3 hypersensitivity
Hypersensitivity IV, - CORRECT ANSWER--is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune - CORRECT ANSWER--diseases in which the body makes antibodies
directed against its own tissues
-
Primary immunodeficiency - CORRECT ANSWER--Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency - CORRECT ANSWER--acquired
Common cause of secondary immunodeficiency - CORRECT ANSWER-Malnutrition
Most patients diagnosed with SLE will have a positive ? - CORRECT ANSWER-
antinuclear antibody (ANA)
SLE (lupus) - CORRECT ANSWER--Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity? - CORRECT ANSWER-
Glomerulonephritis
Sjogren's syndrome - CORRECT ANSWER-Inflammation in salivary and lacrimal glands
SLE - CORRECT ANSWER-Autoantibodies and auto-active t-cells against DNA and
nucleoprotein
Sjögren's syndrome immune changes: - CORRECT ANSWER-Autoantibodies and auto-
reactive t-cells against apoptotic cells
rheumatoid arthritis manifestations: - CORRECT ANSWER-Joint inflammation, stiffness,
pain, loss of range of motion
Rheumatoid Arthritis immune changes: - CORRECT ANSWER-T-cells and B cells
against joint associated antigens
MS manifestations - CORRECT ANSWER-Formation of sclerotic plaque in the brain,
leads to Muscle weakness and ataxia
AND ANSWERS
Hypersensitivity: Type 1 - CORRECT ANSWER--Mediated IgE
-inflammation due to mast cell degranultion
-anaphylactic, asthma, hay fever
treatment: epinephrine
Hypersensitivity: Type 2 - CORRECT ANSWER--Cytotoxic reaction: tissue specific
-binds to the antigen ON THE CELL SURFACE
-macrophages are primary effectors cells involved
cause tissue damage or alter function
Hypersensitivity 2 - CORRECT ANSWER--Graves Disease (hyperthyroidism) -alters
function not destroy
-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or
lysis
-drug allergies
-hemolytic anemia
Hypersensitivity: type 3 - CORRECT ANSWER--Not organ specific
-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released
into the blood or bodily fluids, and the complex is then deposited in the tissues
Hypersensitivity: Type 3 - CORRECT ANSWER--rheumatoid arthritis
-Systemic Lupus Erythematosus (SLE)
-Raynaud's
Hives (urticaria) - CORRECT ANSWER-Hypersensitivity Type 1
First responders to innate the immune system - CORRECT ANSWER-Neutrophils
Allergic contact dermatitis - CORRECT ANSWER-Hypersensitivity Type IV
Type 2 cytotoxic hypersensitivity mediated by: - CORRECT ANSWER--IgG IgM
-macrophages are primary effort cells
, -
Serum Sickness - CORRECT ANSWER-type 3 hypersensitivity
Hypersensitivity IV, - CORRECT ANSWER--is more of a delayed immune response.
-mediated T-cells attack tissue directly (no antibodies)
Autoimmune - CORRECT ANSWER--diseases in which the body makes antibodies
directed against its own tissues
-
Primary immunodeficiency - CORRECT ANSWER--Genetic; inherited
-result of single gene defects
-B and T cell deficiencies
secondary immunodeficiency - CORRECT ANSWER--acquired
Common cause of secondary immunodeficiency - CORRECT ANSWER-Malnutrition
Most patients diagnosed with SLE will have a positive ? - CORRECT ANSWER-
antinuclear antibody (ANA)
SLE (lupus) - CORRECT ANSWER--Facial rash
-vasculitis
- tissue inflammation
Renal disease associated with autoimmunity? - CORRECT ANSWER-
Glomerulonephritis
Sjogren's syndrome - CORRECT ANSWER-Inflammation in salivary and lacrimal glands
SLE - CORRECT ANSWER-Autoantibodies and auto-active t-cells against DNA and
nucleoprotein
Sjögren's syndrome immune changes: - CORRECT ANSWER-Autoantibodies and auto-
reactive t-cells against apoptotic cells
rheumatoid arthritis manifestations: - CORRECT ANSWER-Joint inflammation, stiffness,
pain, loss of range of motion
Rheumatoid Arthritis immune changes: - CORRECT ANSWER-T-cells and B cells
against joint associated antigens
MS manifestations - CORRECT ANSWER-Formation of sclerotic plaque in the brain,
leads to Muscle weakness and ataxia
