Page 1 of 30
PN PHARMACOLOGY EXAM 3 QUESTIONS
WITH CORRECT ANSWERS NEWEST 2026
VERIFIED 100%
Can you take thiazide diuretics with renal impairement?
No - contraindicated in patients with renal impairment
Can you use thiazide diuretics in patients with renal failure?
Not effective in patients with severe renal failure
Do thiazide diuretics cause risk of hearing loss?
No risk of hearing loss & can be combined with ototoxic medications
Do you need to assess for a sulfa allergy with Thiazide diuretics?
sulfa based - assess for sulfa allergy
Furosemide can cause _________ especially when given IV
ototoxicity
Give an example of a carbonic anhydrase inhibitors diuretic?
acetazolamide (Diamox)
Give an example of an osmotic diuretic?
mannitol
how does thiazide diuretics affect osteoporosis?
Promotes reabsorption of calcium and can reduce the risks for postmenopausal
osteoporosis.
, Page 2 of 30
How do osmotic diuretics work?
Reduce intracranial pressure & intraocular pressure by raising serum osmolality and
drawing fluid back into the vascular and extravascular.
How do potassium sparing diuretics work?
MOA: either by blocking sodium or by blocking aldosterone, the hormone that
controls renal reabsorption of sodium and potassium.
How do thiazide diuretics work?
MOA: block Na+ reabsorption and increase potassium and water excretion
How should hydrochlorothiazide be taken with regards to food? - HCTZ
The client should take HCTZ with or after meals to prevent gastrointestinal upset
Hydrochlorothiazide does what to blood sugar?
Increases - hyperglycemia. Patient may need more insulin
If a patient is prescribed furosemide BID, when should you administer the
medication?
08:00 & 14:00 to prevent nocturia
If a patient is prescribed furosemide one time per day when should you
administer the medication?
08:00 prevent nocturia
_______________ is a side effect of a thiazide diuretics and this could lead to
symptoms resembling _______.
Hyperuricemia is a side effect of thiazide diuretics and this could lead to symptoms
resembling gout.
Mannitol (osmotic diuretic) can cause a fluid shift into the vascular space and
the client should be monitored for signs of ____________.
Heart Failure - dyspnea, crackles, fluid-overload
, Page 3 of 30
Mannitol is used to decrease intracranial pressure. Thinking about this, what
should you assess the patient for?
S/S of increased intracranial pressure like vomiting, headache, altered level of
consciousness.
What kind of needle do you need for Mannitol?
filter needle and filter IV tubing
Name one drug that is a potassium sparing diuretic.
Spironolactone
Renal impairment is a contraindication to the administration of what diuretic?
Thiazide diuretic
Should a patient taking a potassium sparing diuretic use salt substitutes?
No, because they contain a lot of potassium.
Should you instruct clients to administer foods high in potassium with a loop
diuretic?
Yes
Should you instruct clients to administer foods high in potassium with a
thiazide diuretic?
Yes
What are Carbonic Anhydrase Inhibitors diuretics used to treat?
Primary use: to decrease intraocular fluid pressure in patients with open-angle
glaucoma.
What are manifestations of ototoxicity?
Report manifestations of ototoxicity such as tinnitus or hearing loss.
What are osmotic diuretics used to treat?
PN PHARMACOLOGY EXAM 3 QUESTIONS
WITH CORRECT ANSWERS NEWEST 2026
VERIFIED 100%
Can you take thiazide diuretics with renal impairement?
No - contraindicated in patients with renal impairment
Can you use thiazide diuretics in patients with renal failure?
Not effective in patients with severe renal failure
Do thiazide diuretics cause risk of hearing loss?
No risk of hearing loss & can be combined with ototoxic medications
Do you need to assess for a sulfa allergy with Thiazide diuretics?
sulfa based - assess for sulfa allergy
Furosemide can cause _________ especially when given IV
ototoxicity
Give an example of a carbonic anhydrase inhibitors diuretic?
acetazolamide (Diamox)
Give an example of an osmotic diuretic?
mannitol
how does thiazide diuretics affect osteoporosis?
Promotes reabsorption of calcium and can reduce the risks for postmenopausal
osteoporosis.
, Page 2 of 30
How do osmotic diuretics work?
Reduce intracranial pressure & intraocular pressure by raising serum osmolality and
drawing fluid back into the vascular and extravascular.
How do potassium sparing diuretics work?
MOA: either by blocking sodium or by blocking aldosterone, the hormone that
controls renal reabsorption of sodium and potassium.
How do thiazide diuretics work?
MOA: block Na+ reabsorption and increase potassium and water excretion
How should hydrochlorothiazide be taken with regards to food? - HCTZ
The client should take HCTZ with or after meals to prevent gastrointestinal upset
Hydrochlorothiazide does what to blood sugar?
Increases - hyperglycemia. Patient may need more insulin
If a patient is prescribed furosemide BID, when should you administer the
medication?
08:00 & 14:00 to prevent nocturia
If a patient is prescribed furosemide one time per day when should you
administer the medication?
08:00 prevent nocturia
_______________ is a side effect of a thiazide diuretics and this could lead to
symptoms resembling _______.
Hyperuricemia is a side effect of thiazide diuretics and this could lead to symptoms
resembling gout.
Mannitol (osmotic diuretic) can cause a fluid shift into the vascular space and
the client should be monitored for signs of ____________.
Heart Failure - dyspnea, crackles, fluid-overload
, Page 3 of 30
Mannitol is used to decrease intracranial pressure. Thinking about this, what
should you assess the patient for?
S/S of increased intracranial pressure like vomiting, headache, altered level of
consciousness.
What kind of needle do you need for Mannitol?
filter needle and filter IV tubing
Name one drug that is a potassium sparing diuretic.
Spironolactone
Renal impairment is a contraindication to the administration of what diuretic?
Thiazide diuretic
Should a patient taking a potassium sparing diuretic use salt substitutes?
No, because they contain a lot of potassium.
Should you instruct clients to administer foods high in potassium with a loop
diuretic?
Yes
Should you instruct clients to administer foods high in potassium with a
thiazide diuretic?
Yes
What are Carbonic Anhydrase Inhibitors diuretics used to treat?
Primary use: to decrease intraocular fluid pressure in patients with open-angle
glaucoma.
What are manifestations of ototoxicity?
Report manifestations of ototoxicity such as tinnitus or hearing loss.
What are osmotic diuretics used to treat?
