Page 1 of 44
PHARMACOLOGY EXAM 1 PRACTICE
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Johns Hopkins University
School of Nursing
HIGH YIELDS QUESTIONS
NEWEST MODEL 2026 EXAM LATEST
VERSION SOLVED QUESTIONS &
ANSWERS VERIFIED 100 %
Exam
, Page 2 of 44
PHARMACOLOGY EXAM 1 PRACTICE QUESTIONS
The nurse cares for a patient who is taking a calcium channel blocker for
hypertension. The nurse should be most concerned if the patient makes which
statement?
A. "I take my medication with a glass of water."
B. "I eat foods high in fiber to prevent constipation."
C. "I drink a glass of grapefruit juice each evening."
D. "I avoid foods such as broccoli and cabbage."
C. "I drink a glass of grapefruit juice each evening."
A patient is prescribed a medication to be taken on an empty stomach. Which
statement should the nurse include when providing patient teaching?
A. "Take the medication 1 hour before eating."
B. "Take the medication with a small glass of water."
C. "Take the medication before going to bed at night."
D. "Take the medication 1 hour after a meal."
A. "Take the medication 1 hour before eating."
Which organ is primarily responsible for eliminating drugs from the body?
A. Liver
B. Kidneys
C. Lungs
D. Skin
B. Kidneys
Please name the active transporter that can be found in the kidneys to help
move compounds into the urine.
P glycoprotein
protein pump
, Page 3 of 44
P- aminoglycosylated amino
M- alpha polaris
P glycoprotein
Nitroglycerin has a very very high first pass effect. To avoid losing essentially
all of the effect from a dose it is administered:
A. PO
B. SL
C. As a smaller dose than normal
D. As a sustained release formula
B. SL
A drug's half life is:
A. Half the time needed to achieve steady state
B. The time needed to eliminate half of a drug's given dose
C. Shortened in liver and/or renal failure
D. Highly unpredictable
B. The time needed to eliminate half of a drug's given dose
When the first dose of a medication is given in a larger than normal dose it is
called ... ?
A. Loading dose
B. Therapeutic dose
C. Maintenance dose
D. Rescue dose
E. A medication error
A. Loading Dose
Your drug is excreted by the kidney, it is renally toxic and your patient has
kidney failure. Can your patient take the drug?
, Page 4 of 44
A. Yes, in some circumstances, you HAVE to give a drug that is excreted by
the kidneys. You would monitor the serum creatinine and creatinine clearance
closely
B. No way
C. Call the supervisor - this is a potential med error
D. Tell the patient that it is his or her own responsibility to monitor issues
A. Yes, in some circumstances, you HAVE to give a drug that is excreted by the
kidneys. You would monitor the serum creatinine and creatinine clearance closely
Grapefruit juice is banned in hospitals because it:
A. tastes terrible
B. inhibits the metabolism of certain drugs via inhibiting CYP3A4
C. enhances CYP2C19
D. increases the acidity in the stomach
B. inhibits the metabolism of certain drugs via inhibiting CYP3A4
What can alter absorption?
A. increasing gastric pH
B. laxatives can alter absorption in the intestines
C. depression of peristalsis (eg morphine)
D. all of the above
D. all of the above
Which of the following statements are TRUE?
PHARMACOLOGY EXAM 1 PRACTICE
Download now
Johns Hopkins University
School of Nursing
HIGH YIELDS QUESTIONS
NEWEST MODEL 2026 EXAM LATEST
VERSION SOLVED QUESTIONS &
ANSWERS VERIFIED 100 %
Exam
, Page 2 of 44
PHARMACOLOGY EXAM 1 PRACTICE QUESTIONS
The nurse cares for a patient who is taking a calcium channel blocker for
hypertension. The nurse should be most concerned if the patient makes which
statement?
A. "I take my medication with a glass of water."
B. "I eat foods high in fiber to prevent constipation."
C. "I drink a glass of grapefruit juice each evening."
D. "I avoid foods such as broccoli and cabbage."
C. "I drink a glass of grapefruit juice each evening."
A patient is prescribed a medication to be taken on an empty stomach. Which
statement should the nurse include when providing patient teaching?
A. "Take the medication 1 hour before eating."
B. "Take the medication with a small glass of water."
C. "Take the medication before going to bed at night."
D. "Take the medication 1 hour after a meal."
A. "Take the medication 1 hour before eating."
Which organ is primarily responsible for eliminating drugs from the body?
A. Liver
B. Kidneys
C. Lungs
D. Skin
B. Kidneys
Please name the active transporter that can be found in the kidneys to help
move compounds into the urine.
P glycoprotein
protein pump
, Page 3 of 44
P- aminoglycosylated amino
M- alpha polaris
P glycoprotein
Nitroglycerin has a very very high first pass effect. To avoid losing essentially
all of the effect from a dose it is administered:
A. PO
B. SL
C. As a smaller dose than normal
D. As a sustained release formula
B. SL
A drug's half life is:
A. Half the time needed to achieve steady state
B. The time needed to eliminate half of a drug's given dose
C. Shortened in liver and/or renal failure
D. Highly unpredictable
B. The time needed to eliminate half of a drug's given dose
When the first dose of a medication is given in a larger than normal dose it is
called ... ?
A. Loading dose
B. Therapeutic dose
C. Maintenance dose
D. Rescue dose
E. A medication error
A. Loading Dose
Your drug is excreted by the kidney, it is renally toxic and your patient has
kidney failure. Can your patient take the drug?
, Page 4 of 44
A. Yes, in some circumstances, you HAVE to give a drug that is excreted by
the kidneys. You would monitor the serum creatinine and creatinine clearance
closely
B. No way
C. Call the supervisor - this is a potential med error
D. Tell the patient that it is his or her own responsibility to monitor issues
A. Yes, in some circumstances, you HAVE to give a drug that is excreted by the
kidneys. You would monitor the serum creatinine and creatinine clearance closely
Grapefruit juice is banned in hospitals because it:
A. tastes terrible
B. inhibits the metabolism of certain drugs via inhibiting CYP3A4
C. enhances CYP2C19
D. increases the acidity in the stomach
B. inhibits the metabolism of certain drugs via inhibiting CYP3A4
What can alter absorption?
A. increasing gastric pH
B. laxatives can alter absorption in the intestines
C. depression of peristalsis (eg morphine)
D. all of the above
D. all of the above
Which of the following statements are TRUE?
