General Pharmacology Notes

Detailed Title of the topic 1. General Pharmacology a) Introduction, definitions and scope of pharmacology b) Routes of administration of drugs c) Pharmacokinetics (absorption, distribution, metabolism and excretion) d) Pharmacodynamics e) Factors modifying drug effects f) Drug toxicity - Acute, sub- acute and chronic toxicity. g) Pre-clinical evaluations h) Drug interactions Note: The term Pharmacology used here refers to the classification, mechanism of action, pharmacokinetics, pharmacodynamics, adverse effects, contraindications, Therapeutic uses, interactions and dose and route of administration. 2. Pharmacology of drugs acting on ANS a) Adrenergic and antiadrenergic drugs b) Cholinergic and anticholinergic drugs c) Neuromuscular blockers d) Mydriactics and miotics e) Drugs used in myasthenia gravis f) Drugs used in Parkinsonism 3. Pharmacology of drugs acting on cardiovascular system a) Antihypertensives b) Anti-anginal drugs c) Anti-arrhythmic drugs d) Drugs used for therapy of Congestive Heart Failure e) Drugs used for hyperlipidaemias 4. Pharmacology of drugs acting on Central Nervous System a) General anesthetics b) Sedatives and hypnotics c) Anticonvulsants d) Analgesic and anti- inflammatory agents e) Psychotropic drugs f) Alcohol and methyl alcohol g) CNS stimulants and cognition enhancers h) Pharmacology of local anaesthetics 5. Pharmacology of Drugs acting on Respiratory tract a) Bronchodilators b) Mucolytics c) Expectorants d) Antitussives e) NasalDecongestants 6. Pharmacology of Hormones and Hormone antagonists a) Thyroid and Antithyroid drugs b) Insulin, Insulin analogues and oral hypoglycemic agents c) Sex hormones and oral contraceptives d) Oxytocin and other stimulants and relaxants 7. Pharmacology of autocoids and their antagonists a) Histamines and Antihistaminics b) 5-Hydroxytryptamine and its antagonists c) Lipid derived autocoids and platelet activating factor