Moleculaire Genetica 1
Lijst van trefwoorden
Week 1
College 1 (inleiding)
1
,cel transcriptie ortholoog
archaebacteriën RNA paraloog
eubacteriën translatie homoloog
prokaryoten eiwit (protein) genfamilie
eukaryoten aminozuur reverse genetics
DNA enzym haploid
chromosoom mutant diploid
gen mutatie
genoom gen duplicatie
replicatie horizontal transfer
College 2 (DNA)
ribose thymine 3’ kant
deoxyribose thymidine waterstofbrug
nucleoside uracil basepaar
nucleotide uridine antiparallel
purine nucleoside monofosfaat minor groove
pyrimidine nucleoside difosfaat major groove
adenine nucleoside trifosfaat plasmide
adenosine ATP, GDP, dTTP, dCMP uitsmelten/denatureren
guanine etc hybridiseren/renaturere
guanidine fosfoanhydride band n
cytosine fosfodiester band
cytidine 5’ kant
College 3+4 (supercoiling en histonen)
topologie karyotype epigenetica
ontwinding van DNA histon Barr body
positieve supercoiling nucleosoom chromatine remodeling
negatieve supercoiling linker histon histon modificatie
relaxed DNA 30 nm fiber acetylering
topoisomerase I solenoid methylering
topoisomerase II euchromatine fosforylering
chromatine heterochromatine histon code
2
, Week 2
College 5+6 (DNA synthese)
replicatie primer MutS
pyrofosfaat primase MutL
DNA polymerase RNase MutH
template DNA ligase Dam methylase
exonuclease DNA helicase hemimethylering
proofreading allosterisch effect origin
replicatievork SSB (single strand initiatie van replicatie
leading strand binding DnaA
synthese protein) bidirectionele replicatie
lagging strand sliding clamp terminatie van
synthese clamp loader replicatie
Okazaki fragment mismatch repair
College 7 (Replicatie in eukaryoten)
cel cyclus centromeer reader-writer complex
G1 fase ORC (origin recognition epigenetica
S fase complex) telomerase
G2 fase histon chaperone reverse transcriptase
M fase chromatin assembly t-loop
telomere factor
College 8 (DNA repair)
DNA damage thymine dimeer fosfodiesterase
depurinering base excision repair nucleotide excision
deaminering DNA glycosylase repair
zuurstof radicalen AP endonuclease
3
Lijst van trefwoorden
Week 1
College 1 (inleiding)
1
,cel transcriptie ortholoog
archaebacteriën RNA paraloog
eubacteriën translatie homoloog
prokaryoten eiwit (protein) genfamilie
eukaryoten aminozuur reverse genetics
DNA enzym haploid
chromosoom mutant diploid
gen mutatie
genoom gen duplicatie
replicatie horizontal transfer
College 2 (DNA)
ribose thymine 3’ kant
deoxyribose thymidine waterstofbrug
nucleoside uracil basepaar
nucleotide uridine antiparallel
purine nucleoside monofosfaat minor groove
pyrimidine nucleoside difosfaat major groove
adenine nucleoside trifosfaat plasmide
adenosine ATP, GDP, dTTP, dCMP uitsmelten/denatureren
guanine etc hybridiseren/renaturere
guanidine fosfoanhydride band n
cytosine fosfodiester band
cytidine 5’ kant
College 3+4 (supercoiling en histonen)
topologie karyotype epigenetica
ontwinding van DNA histon Barr body
positieve supercoiling nucleosoom chromatine remodeling
negatieve supercoiling linker histon histon modificatie
relaxed DNA 30 nm fiber acetylering
topoisomerase I solenoid methylering
topoisomerase II euchromatine fosforylering
chromatine heterochromatine histon code
2
, Week 2
College 5+6 (DNA synthese)
replicatie primer MutS
pyrofosfaat primase MutL
DNA polymerase RNase MutH
template DNA ligase Dam methylase
exonuclease DNA helicase hemimethylering
proofreading allosterisch effect origin
replicatievork SSB (single strand initiatie van replicatie
leading strand binding DnaA
synthese protein) bidirectionele replicatie
lagging strand sliding clamp terminatie van
synthese clamp loader replicatie
Okazaki fragment mismatch repair
College 7 (Replicatie in eukaryoten)
cel cyclus centromeer reader-writer complex
G1 fase ORC (origin recognition epigenetica
S fase complex) telomerase
G2 fase histon chaperone reverse transcriptase
M fase chromatin assembly t-loop
telomere factor
College 8 (DNA repair)
DNA damage thymine dimeer fosfodiesterase
depurinering base excision repair nucleotide excision
deaminering DNA glycosylase repair
zuurstof radicalen AP endonuclease
3
