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Chapter 43: Drugs Used to Treat Cancer
MULTIPLE CHOICE
1. The nurse is educating a patient with cancer about combination chemotherapy. Which is an
accurate statement?
a. “Combination chemotherapy is the administration of an antineoplastic drug that will be
toxic during a specific phase of cellular growth.”
b. “Combination chemotherapy is the administration of an antineoplastic drug that is active
throughout the cell cycle.”
c. “Combination chemotherapy is the administration of antineoplastic drugs that change the
way the body responds to cancer or strengthens the immune system.”
d. “Combination chemotherapy is the administration of antineoplastic drugs, which results
in cell death during different phases of the cell cycle.”
ANS: D
Use of combination drug therapy is superior in therapeutic effect to the use of single agent
chemotherapy.
DIF: Cognitive Level: ComprehensionREF: Page 669 OBJ: 1
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Patient Education
2. The cell cycle-specific agent vincristine sulphate (Oncovin) acts in which phase of the cell’s
life cycle?
a. S phase
b. Mitotic phase
c. Phase G1
d. Phase G0
ANS: B
Vinca alkaloids block the formation of the mitotic spindle during mitosis, thus inhibiting cell
division. The S phase is the stage of active synthesis of two sets of DNA. Phase G 1 is
considered a presynthetic phase in which the cell prepares for DNA synthesis by
manufacturing necessary enzymes. G0 is the largest variable in the cell cycle and, during this
resting phase, the cell is not actively replicating.
DIF: Cognitive Level: Knowledge REF: Page 667 | Page 668
OBJ: 1 TOP: Nursing Process Step: Implementation
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MSC:
NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment
3. What is the importance of correlating the dosage schedule with cell cycle-specific drug
therapy?
a. Ongoing proliferation of neoplastic tissue
Combination therapy is far superior to the use of single agent therapy. The use of a cell
cyclespecific and cell cycle-nonspecific agents together facilitates cell death during different
phases of the cell cycle. Combination therapy is not more economical or faster. Combination
therapy is not less toxic because it exposes patients and nurses to additional medications.
The use of combination drug therapy allows for cell death during different phases of the cell
cycle, but the agents often have toxic effects on different organs at different time intervals
after administration.
DIF: Cognitive Level: ComprehensionREF: Page 669 OBJ: 2
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity NOT:
CONCEPT(S): Clinical Judgment
6. Why is a patient with prostate cancer prescribed an estrogen?
a. To achieve hormonal balance
b. To decrease the rate of production for malignant cells
c. To soften prostatic tissue
d. To suppress prostate gland function
ANS: B
Estrogen therapy is used during the treatment of prostate cancer to decrease the rate of
production of malignant cells. The use of female hormones decreases the amount of male
hormones available for use by the cancer cells. Estrogen is not given for hormonal balance,
does not soften prostatic tissue, and does not suppress prostate gland function.
DIF: Cognitive Level: ComprehensionREF: Page 669 OBJ: 1
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity NOT:
CONCEPT(S): Clinical Judgment
7. Which assessment by the nurse would be a sign of neurotoxicity related to chemotherapy?
a. Paresthesia
b. Euphoria
c. Nausea
d. Hallucinations
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Chapter 43: Drugs Used to Treat Cancer
MULTIPLE CHOICE
1. The nurse is educating a patient with cancer about combination chemotherapy. Which is an
accurate statement?
a. “Combination chemotherapy is the administration of an antineoplastic drug that will be
toxic during a specific phase of cellular growth.”
b. “Combination chemotherapy is the administration of an antineoplastic drug that is active
throughout the cell cycle.”
c. “Combination chemotherapy is the administration of antineoplastic drugs that change the
way the body responds to cancer or strengthens the immune system.”
d. “Combination chemotherapy is the administration of antineoplastic drugs, which results
in cell death during different phases of the cell cycle.”
ANS: D
Use of combination drug therapy is superior in therapeutic effect to the use of single agent
chemotherapy.
DIF: Cognitive Level: ComprehensionREF: Page 669 OBJ: 1
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment; Patient Education
2. The cell cycle-specific agent vincristine sulphate (Oncovin) acts in which phase of the cell’s
life cycle?
a. S phase
b. Mitotic phase
c. Phase G1
d. Phase G0
ANS: B
Vinca alkaloids block the formation of the mitotic spindle during mitosis, thus inhibiting cell
division. The S phase is the stage of active synthesis of two sets of DNA. Phase G 1 is
considered a presynthetic phase in which the cell prepares for DNA synthesis by
manufacturing necessary enzymes. G0 is the largest variable in the cell cycle and, during this
resting phase, the cell is not actively replicating.
DIF: Cognitive Level: Knowledge REF: Page 667 | Page 668
OBJ: 1 TOP: Nursing Process Step: Implementation
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 18:22:56 GMT -05:00
https://www.coursehero.com/file/36140308/c43rtf/
Downloaded by: Sophiie |
Distribution of this document is illegal
, Stuvia.com - The Marketplace to Buy and Sell your Study Material
MSC:
NCLEX Client Needs Category: Physiological Integrity
NOT: CONCEPT(S): Clinical Judgment
3. What is the importance of correlating the dosage schedule with cell cycle-specific drug
therapy?
a. Ongoing proliferation of neoplastic tissue
Combination therapy is far superior to the use of single agent therapy. The use of a cell
cyclespecific and cell cycle-nonspecific agents together facilitates cell death during different
phases of the cell cycle. Combination therapy is not more economical or faster. Combination
therapy is not less toxic because it exposes patients and nurses to additional medications.
The use of combination drug therapy allows for cell death during different phases of the cell
cycle, but the agents often have toxic effects on different organs at different time intervals
after administration.
DIF: Cognitive Level: ComprehensionREF: Page 669 OBJ: 2
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity NOT:
CONCEPT(S): Clinical Judgment
6. Why is a patient with prostate cancer prescribed an estrogen?
a. To achieve hormonal balance
b. To decrease the rate of production for malignant cells
c. To soften prostatic tissue
d. To suppress prostate gland function
ANS: B
Estrogen therapy is used during the treatment of prostate cancer to decrease the rate of
production of malignant cells. The use of female hormones decreases the amount of male
hormones available for use by the cancer cells. Estrogen is not given for hormonal balance,
does not soften prostatic tissue, and does not suppress prostate gland function.
DIF: Cognitive Level: ComprehensionREF: Page 669 OBJ: 1
TOP: Nursing Process Step: Evaluation
MSC: NCLEX Client Needs Category: Physiological Integrity NOT:
CONCEPT(S): Clinical Judgment
7. Which assessment by the nurse would be a sign of neurotoxicity related to chemotherapy?
a. Paresthesia
b. Euphoria
c. Nausea
d. Hallucinations
This study source was downloaded by 100000761823232 from CourseHero.com on 04-12-2021 18:22:56 GMT -05:00
https://www.coursehero.com/file/36140308/c43rtf/
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