GRADE
1. What are the uses for anticoagulants? - inhibit clot formation, prevent new clots from forming
2. Do anticoagulants dissolve clots? - no
3. What are anti-platelets used for? - prevent thrombus in arteries
4. Thrombolytics cause what? - thrombi to dissolve
5. PT and INR labs are used for what therapy? - warfarin
6. Partial thromboplastin time (PTT) and activated partial thromboplastin time is used for what therapy? - Heparin
7. What labs help measure coagulation? - PT, INR, PTT, aPTT, platelet count and liver function
8. What is the action of heparin? - interferes with normal coagulation and thrombin formation
9. What are the uses of heparin? - DVT, PE, evolving stroke
10. What is the reversal agent for heparin? - protamine sulfate
11. What labs do you need to monitor while on heparin? - aPTT and PTT
12. How is heparin administered? - IV and SUBQ
13. What are the adverse effects of heparin? - bleeding
14. What is the trade name for enoxaparin? - Lovenox
, 15. What is the action for enoxaparin (lovenox)? - causes fewer adverse effects and has predictable response
16. What are the uses for enoxaparin (lovenox)? - orthopedic or abdominal surgery
17. enoxaparin (lovenox) is continued for how many days after surgery? - 7-10
18. What is the reversal agent for enoxaparin (lovenox)? - Protamine sulfate
19. Can enoxaparin (lovenox) be administered at home? - yes
20. What are the contradictions for enoxaparin (lovenox)? - strokes, peptic ulcers, blood anomalies
21. enoxaparin (lovenox) is what type of heparin? - low molecular weight
22. Low molecular weight heparin should not be given to patients with what? - eyes, brain, spinal surgery
23. Oral anticoagulant therapy inhibits the synthesis of what? - vitamin K
24. What is the oral anticoagulant therapy? - warfarin
25. What is the trade name of warfarin? - Coumadin
26. What labs do you need to monitor when giving warfarin (Coumadin)? - PT and INR
27. What is the reversal agent for warfarin (Coumadin)? - vitamin K
28. Excessive bleeding from warfarin (Coumadin) may require what? - fresh frozen plasma, blood, platelets
29. Antiplatelet agents inhibit what? - platelet adhesion and aggregation
30. What are the uses for anti platelet agents? - CV disease, venous and arterial graft maintenance, prevention of
cerebrovascular occlusion, and MI