GALEN PHARM 2500 STUDY GUIDE QUESTIONS WITH COMPLETE ANSWERS
Pharmaceutic Phase Correct Answer: Drug dissolves and into a solution that can cross biologic
membrane
Disintergration Correct Answer: Breakdown of tablet into smaller particles
Dissolution Correct Answer: Dissolving of smaller particles in the GI fluid before absorption
Pharmacokinetic Phase Correct Answer: Made up of Absorption, Distribution, Metabolism
(Bio-transformation) and Excretion (Elimination)
Pharmacodynamic Phase Correct Answer: Onset, Peak, Duration, Therapeutic Range, Side
Effects, Adverse Reactions
Drug distribution Correct Answer: Process where drug becomes available to body fluids and
tissues
Bioavailability Correct Answer: Percentage of administered drug that actually reaches systemic
circulation
First-pass effect Correct Answer: Where drug passes to liver first
Absorption Correct Answer: Movement of drug particles from GI tract to body fluids by passive
transport or active transport
Metabolism (Bio-transformation) Correct Answer: Liver is primary site.
Excretion Correct Answer: Drug is eliminated from body in urine.
Potassium (Lab value) Correct Answer: 3.5-5
Creatinine (Lab value) Correct Answer: 0.5-1.2
BUN (Lab value) Correct Answer: 10-20
WBC (Lab value) Correct Answer: 5-10
Vancomycin (Lab value) Correct Answer: 20-40
Gentamicin Correct Answer: 5-10
Glomerular Filtration Rate (GFR)/ Creatinine Clearance (Lab value) Correct Answer: 90-120
Albumin (Lab value) Correct Answer: 3.5-5
, Additive Correct Answer: The combined effect of two drugs
Synergistic Correct Answer: Combined effect of two drugs that is greater than their original
effects combined
Antagonistic Correct Answer: The decrease of a drugs effect when another drug is added
Allergic reaction Correct Answer: Things such as Rash, Itching, Hives, Swelling,Dyspnea
Side effect Correct Answer: An effect secondary to the intended effect of drug.
Adverse effect Correct Answer: Side effects that often require medical attention.
Therapeutic effect Correct Answer: The desired action of a drug
Drug onset Correct Answer: the time required after administration of a drug for a response to be
observed.
Duration of meds Correct Answer: How long a medication remains working
Peak Correct Answer: Highest level of concentration in a patients bloodstream
Trough Correct Answer: The lowest concentration in a patients bloodstream
Polypharmacy prevention Correct Answer: obtain full list of all medications client is taking
ask about all medical providers
Teach when to stop medications especially when new ones are prescribed.
Atropine Sulfate Correct Answer: Antidote for Cholinergic Crisis
Anticholinergics Correct Answer: • Inhibits the actions of acetylcholine by occupying the
receptors
Anticholinergics Correct Answer: • Also called parasympatholytics, cholinergic blocking agents
Anticholinergics Correct Answer: • Sites of action
Heart, respiratory tract, GI, Urinary bladder, eyes and exocrine glands
Anticholinergics Correct Answer: • Major response is decreased GI motility, decreased
salivation, dilation of the pupils, and increase pulse, decrease bladder contraction
Anticholinergics • Side effects Correct Answer: o Dry mouth, dry eyes, blurred vision,
tachycardia, constipation, urinary retention, decreased sweating
Pharmaceutic Phase Correct Answer: Drug dissolves and into a solution that can cross biologic
membrane
Disintergration Correct Answer: Breakdown of tablet into smaller particles
Dissolution Correct Answer: Dissolving of smaller particles in the GI fluid before absorption
Pharmacokinetic Phase Correct Answer: Made up of Absorption, Distribution, Metabolism
(Bio-transformation) and Excretion (Elimination)
Pharmacodynamic Phase Correct Answer: Onset, Peak, Duration, Therapeutic Range, Side
Effects, Adverse Reactions
Drug distribution Correct Answer: Process where drug becomes available to body fluids and
tissues
Bioavailability Correct Answer: Percentage of administered drug that actually reaches systemic
circulation
First-pass effect Correct Answer: Where drug passes to liver first
Absorption Correct Answer: Movement of drug particles from GI tract to body fluids by passive
transport or active transport
Metabolism (Bio-transformation) Correct Answer: Liver is primary site.
Excretion Correct Answer: Drug is eliminated from body in urine.
Potassium (Lab value) Correct Answer: 3.5-5
Creatinine (Lab value) Correct Answer: 0.5-1.2
BUN (Lab value) Correct Answer: 10-20
WBC (Lab value) Correct Answer: 5-10
Vancomycin (Lab value) Correct Answer: 20-40
Gentamicin Correct Answer: 5-10
Glomerular Filtration Rate (GFR)/ Creatinine Clearance (Lab value) Correct Answer: 90-120
Albumin (Lab value) Correct Answer: 3.5-5
, Additive Correct Answer: The combined effect of two drugs
Synergistic Correct Answer: Combined effect of two drugs that is greater than their original
effects combined
Antagonistic Correct Answer: The decrease of a drugs effect when another drug is added
Allergic reaction Correct Answer: Things such as Rash, Itching, Hives, Swelling,Dyspnea
Side effect Correct Answer: An effect secondary to the intended effect of drug.
Adverse effect Correct Answer: Side effects that often require medical attention.
Therapeutic effect Correct Answer: The desired action of a drug
Drug onset Correct Answer: the time required after administration of a drug for a response to be
observed.
Duration of meds Correct Answer: How long a medication remains working
Peak Correct Answer: Highest level of concentration in a patients bloodstream
Trough Correct Answer: The lowest concentration in a patients bloodstream
Polypharmacy prevention Correct Answer: obtain full list of all medications client is taking
ask about all medical providers
Teach when to stop medications especially when new ones are prescribed.
Atropine Sulfate Correct Answer: Antidote for Cholinergic Crisis
Anticholinergics Correct Answer: • Inhibits the actions of acetylcholine by occupying the
receptors
Anticholinergics Correct Answer: • Also called parasympatholytics, cholinergic blocking agents
Anticholinergics Correct Answer: • Sites of action
Heart, respiratory tract, GI, Urinary bladder, eyes and exocrine glands
Anticholinergics Correct Answer: • Major response is decreased GI motility, decreased
salivation, dilation of the pupils, and increase pulse, decrease bladder contraction
Anticholinergics • Side effects Correct Answer: o Dry mouth, dry eyes, blurred vision,
tachycardia, constipation, urinary retention, decreased sweating
