Chapter 14: Cancer in Children (Practice)
1. What congenital malformation is commonly linked to acute leukemia
in children?
a. Down syndrome
b. Wilms tumor
c. Retinoblastoma
d. Neuroblastoma
Notes: Trisomy 21 (Down syndrome) is the most common genetic
defect linked to the development of acute leukemia. Children with
Down syndrome have a 10- to 20-fold increased risk of developing
acute
lymphoblastic and myelogenous leukemia and a higher risk for
developing acute megakaryocytic
leukemia. No current research supports a link between the other stated
congenital malformations and acute leukemia.
2. When are childhood cancers most often diagnosed?
a. During infancy
b. At peak times of physical growth
c. After diagnosis of a chronic illness
d. After an acute illness
3. Prenatal exposure to diethylstilbestrol (DES) can result in which type
of cancer?
a. Breast cancer
b. Leukemia
c. Vaginal cancer
d. Lymphoma
Notes: DES has been identified as a transplacental chemical
carcinogen; a small percentage of the daughters of women who took
DES during pregnancy developed adenocarcinomas of the vagina.
4. Currently, what percentage of children with cancer can be cured?
a. 40%
1/5
, b. 50%
c. 60%
d. 80%
2/5
1. What congenital malformation is commonly linked to acute leukemia
in children?
a. Down syndrome
b. Wilms tumor
c. Retinoblastoma
d. Neuroblastoma
Notes: Trisomy 21 (Down syndrome) is the most common genetic
defect linked to the development of acute leukemia. Children with
Down syndrome have a 10- to 20-fold increased risk of developing
acute
lymphoblastic and myelogenous leukemia and a higher risk for
developing acute megakaryocytic
leukemia. No current research supports a link between the other stated
congenital malformations and acute leukemia.
2. When are childhood cancers most often diagnosed?
a. During infancy
b. At peak times of physical growth
c. After diagnosis of a chronic illness
d. After an acute illness
3. Prenatal exposure to diethylstilbestrol (DES) can result in which type
of cancer?
a. Breast cancer
b. Leukemia
c. Vaginal cancer
d. Lymphoma
Notes: DES has been identified as a transplacental chemical
carcinogen; a small percentage of the daughters of women who took
DES during pregnancy developed adenocarcinomas of the vagina.
4. Currently, what percentage of children with cancer can be cured?
a. 40%
1/5
, b. 50%
c. 60%
d. 80%
2/5
