2023 ATI Pharmacology VERIFIED Questions&Solutions
1. Rocephin belongs to what class of anti-infectives?: 3rd
generation cephalosporin
2. Rocephin, as a cephalosporin, is contraindicated in pts. with
an allergy to this class of anti-infectives: penicillin
3. valporic acid (Depakene) indicated for: seizures
4. valporic acid (Depakene) may carry adverse side effects
such as: thrombo- cytopenia, prolonged bleeding time, life-
threatening hepatotoxicity
5. valporic acid (Depakene) may have toxic effects on this
organ: liver
6. chlorothiazide (Diuril) puts one at risk of this electrolyte
imbalance: hy- pokalemia
7. lactulose (Cephulac) is a laxative given to promote the
excretion of: ammo- nia
8. What doe lactulose (Cephulac) do?: discourages growth of
bacteria, traps ammonia in the gut, expels ammonia from the colon
9. What happens to ammonia levels in liver failure?: ammonia
levels increase in liver failure
10.toxic megacolon is: a condition characterized by paralysis of
colonic peristal- sis resulting in rapid dilatation of the bowel -- the
bowel gets bigger as feces is trapped; symptoms include tachycardia,
fever, abd tenderness/cramping, reduc- tion/cessation of diarrhea
11.filgastrim (Neupogen) is used with clients who have this
decreased count on their CBC: neutophils
12.proteinuria is related to what type of toxicity?: nephrotoxicity
13.gentamicin sulface (Garamycin) is related to this type of
toxicity: nephro- toxicity
14.metoclopramide (Reglan) is used to: control vomiting
associated with chemotherapy, postop vomiting, etc.
15.tamoxifen (Nolvadex) is used in tx of breast cancer; it
belongs to this class of drugs:: anti-estrogenic, antineoplastics
16.amantadine (Symmetrel) belongs to what class of drugs
used to treat extrapyramidal side effects: antiparkinsonian
,drugs
17.Hydroxyzine (Vistaril) belongs to which therapeutic
classes: Antianxiety agents, antihistamines, sedative/hypnotics
,18.This is a common side effect of hydroxyzine (Vistaril): Dry
mouth
19.Why return TPN to pharmacy when noticing a marked
separation of oil droplets from rest of solution?: This is called
cracking of lipid emulsion, and renders the solution unusable.
20.Does bismuth subsalicylate (Pepto Bismol) have anti-
infective properties against H. pylori?: Yes
21.What common GI disorder is caused by H. pylori?: Peptic ulcer
disease
22.Should glucocorticoids be taken on an empty stomach?: No,
because they can cause severe GI distress and lead to ulcer formation
23.Name an acceptable means of reducing the side effects of
long term oral glucocorticoid therapy: Schedule the medication
on alternate days
24.Why avoid tricyclic antidepressants during pregnancy?:
They are associ- ated with fetal anomalies, especially during the first
trimester
25.Amitriptyline (Elavil) is what type of medication?: Tricyclic
antidepressant
26.Risedronate (Actonel): Bisphosphonate used in osteoporosis;
take first thing in morning with glass water at least 30 mins prior to
eating
27.Streptomycin and furosemide taken together increase the
risk for this type of toxicity: Ototoxicity
28.This medication is used in atrial fibrillation: Propranolol
(INDERAL)
29.When the Alpha1 receptors are activated, what response is
expected?: - activation of receptors in arterioles of skin, viscera, and
mucous membranes, and veins lead to VASOCONSTRICTION
30. When the Beta1 receptors are activated, what response is
expected?-
: Heart stimulation leads to increased HR, increase myocardial
contractility, and increased rate of conduction through the AV node
31.When the Beta2 receptors are activated, what response is
expected?: Ac- tivation of receptors in the arterioles of the heart,
, lungs, and skeletal muscles lead to VASODILATION; bronchial
stimulation leads to BRONCHODILATION; activation of receptors in
uterine smooth muscle causes relaxation; activation of receptors in
liver cause glycogenolysis; skeletal muscle receptor activation leads to
muscle contraction
32. When the dopamine receptors are activated, what response
is expected?-
: activation of receptors in the kidney cause the renal blood vessels to
dilate
1. Rocephin belongs to what class of anti-infectives?: 3rd
generation cephalosporin
2. Rocephin, as a cephalosporin, is contraindicated in pts. with
an allergy to this class of anti-infectives: penicillin
3. valporic acid (Depakene) indicated for: seizures
4. valporic acid (Depakene) may carry adverse side effects
such as: thrombo- cytopenia, prolonged bleeding time, life-
threatening hepatotoxicity
5. valporic acid (Depakene) may have toxic effects on this
organ: liver
6. chlorothiazide (Diuril) puts one at risk of this electrolyte
imbalance: hy- pokalemia
7. lactulose (Cephulac) is a laxative given to promote the
excretion of: ammo- nia
8. What doe lactulose (Cephulac) do?: discourages growth of
bacteria, traps ammonia in the gut, expels ammonia from the colon
9. What happens to ammonia levels in liver failure?: ammonia
levels increase in liver failure
10.toxic megacolon is: a condition characterized by paralysis of
colonic peristal- sis resulting in rapid dilatation of the bowel -- the
bowel gets bigger as feces is trapped; symptoms include tachycardia,
fever, abd tenderness/cramping, reduc- tion/cessation of diarrhea
11.filgastrim (Neupogen) is used with clients who have this
decreased count on their CBC: neutophils
12.proteinuria is related to what type of toxicity?: nephrotoxicity
13.gentamicin sulface (Garamycin) is related to this type of
toxicity: nephro- toxicity
14.metoclopramide (Reglan) is used to: control vomiting
associated with chemotherapy, postop vomiting, etc.
15.tamoxifen (Nolvadex) is used in tx of breast cancer; it
belongs to this class of drugs:: anti-estrogenic, antineoplastics
16.amantadine (Symmetrel) belongs to what class of drugs
used to treat extrapyramidal side effects: antiparkinsonian
,drugs
17.Hydroxyzine (Vistaril) belongs to which therapeutic
classes: Antianxiety agents, antihistamines, sedative/hypnotics
,18.This is a common side effect of hydroxyzine (Vistaril): Dry
mouth
19.Why return TPN to pharmacy when noticing a marked
separation of oil droplets from rest of solution?: This is called
cracking of lipid emulsion, and renders the solution unusable.
20.Does bismuth subsalicylate (Pepto Bismol) have anti-
infective properties against H. pylori?: Yes
21.What common GI disorder is caused by H. pylori?: Peptic ulcer
disease
22.Should glucocorticoids be taken on an empty stomach?: No,
because they can cause severe GI distress and lead to ulcer formation
23.Name an acceptable means of reducing the side effects of
long term oral glucocorticoid therapy: Schedule the medication
on alternate days
24.Why avoid tricyclic antidepressants during pregnancy?:
They are associ- ated with fetal anomalies, especially during the first
trimester
25.Amitriptyline (Elavil) is what type of medication?: Tricyclic
antidepressant
26.Risedronate (Actonel): Bisphosphonate used in osteoporosis;
take first thing in morning with glass water at least 30 mins prior to
eating
27.Streptomycin and furosemide taken together increase the
risk for this type of toxicity: Ototoxicity
28.This medication is used in atrial fibrillation: Propranolol
(INDERAL)
29.When the Alpha1 receptors are activated, what response is
expected?: - activation of receptors in arterioles of skin, viscera, and
mucous membranes, and veins lead to VASOCONSTRICTION
30. When the Beta1 receptors are activated, what response is
expected?-
: Heart stimulation leads to increased HR, increase myocardial
contractility, and increased rate of conduction through the AV node
31.When the Beta2 receptors are activated, what response is
expected?: Ac- tivation of receptors in the arterioles of the heart,
, lungs, and skeletal muscles lead to VASODILATION; bronchial
stimulation leads to BRONCHODILATION; activation of receptors in
uterine smooth muscle causes relaxation; activation of receptors in
liver cause glycogenolysis; skeletal muscle receptor activation leads to
muscle contraction
32. When the dopamine receptors are activated, what response
is expected?-
: activation of receptors in the kidney cause the renal blood vessels to
dilate
