Stahl’s Essential Psychopharmacology Fifth Edition
Practice
Questions
Psychopharmac
ology
Includes Chapters: 1,2,3,4,5,6,7,8,9,13
,CHAPTER 1:
Which of the following is NOT a key neurotransmitter system targeted by
psychotropic drugs?
A) Serotonin
B) Norepinephrine
C) Dopamine
D) GABA
Answer: D) GABA
Which of the following is an example of a retrograde neurotransmitter?
A) Dopamine
B) Serotonin
C) Nitric oxide
D) GABA
Answer: C) Nitric oxide
Which enzyme adds phosphate groups to proteins to create phosphoproteins in a
signal transduction cascade?
A. Kinase
B. Phosphatase
C. Synthase
D. Protease
Answer: A. Kinase
Which of the following signal transduction cascades is activated by neurotransmitters
in the brain?
a) G-protein-linked system
b) Ion-channel-linked system
c) Hormone-linked system
d) Neurotrophin-linked system
Answer: a) G-protein-linked system and b) Ion-channel-linked system.
, Which of the following is an example of volume neurotransmission?
A) The release of acetylcholine from a presynaptic neuron to bind with postsynaptic
receptors
B) The release of serotonin from a presynaptic neuron to bind with postsynaptic
receptors
C) The release of dopamine from a presynaptic neuron to bind with extrasynaptic
receptors on neighboring neurons
D) The release of GABA from a presynaptic neuron to bind with ionotropic receptors
on postsynaptic neurons
Answer: C) The release of dopamine from a presynaptic neuron to bind with
extrasynaptic receptors on neighboring neurons.
Which enzyme is responsible for continuously pumping sodium out of the neuron to
create a gradient that powers the transport of neurotransmitters?
a) Serotonin transporter
b) Sodium–potassium ATPase
c) Vesicular monoamine transporter
d) Proton ATPase
Answer: b) Sodium–potassium ATPase
Which transporter is responsible for transporting serotonin, norepinephrine,
dopamine, and histamine into synaptic vesicles?
a) Vesicular monoamine transporter (VMAT2)
b) Vesicular acetylcholine transporter (VAChT)
c) Vesicular inhibitory amino acid transporter (VIAAT)
d) Vesicular glutamate transporter (VGluT)
Answer: a) Vesicular monoamine transporter (VMAT2)
CHAPTER 2:
Which of the following is true about inverse agonists?
A) They have no activity of their own in the absence of the agonist
B) They can reduce activity below the baseline level when no agonist is present
Practice
Questions
Psychopharmac
ology
Includes Chapters: 1,2,3,4,5,6,7,8,9,13
,CHAPTER 1:
Which of the following is NOT a key neurotransmitter system targeted by
psychotropic drugs?
A) Serotonin
B) Norepinephrine
C) Dopamine
D) GABA
Answer: D) GABA
Which of the following is an example of a retrograde neurotransmitter?
A) Dopamine
B) Serotonin
C) Nitric oxide
D) GABA
Answer: C) Nitric oxide
Which enzyme adds phosphate groups to proteins to create phosphoproteins in a
signal transduction cascade?
A. Kinase
B. Phosphatase
C. Synthase
D. Protease
Answer: A. Kinase
Which of the following signal transduction cascades is activated by neurotransmitters
in the brain?
a) G-protein-linked system
b) Ion-channel-linked system
c) Hormone-linked system
d) Neurotrophin-linked system
Answer: a) G-protein-linked system and b) Ion-channel-linked system.
, Which of the following is an example of volume neurotransmission?
A) The release of acetylcholine from a presynaptic neuron to bind with postsynaptic
receptors
B) The release of serotonin from a presynaptic neuron to bind with postsynaptic
receptors
C) The release of dopamine from a presynaptic neuron to bind with extrasynaptic
receptors on neighboring neurons
D) The release of GABA from a presynaptic neuron to bind with ionotropic receptors
on postsynaptic neurons
Answer: C) The release of dopamine from a presynaptic neuron to bind with
extrasynaptic receptors on neighboring neurons.
Which enzyme is responsible for continuously pumping sodium out of the neuron to
create a gradient that powers the transport of neurotransmitters?
a) Serotonin transporter
b) Sodium–potassium ATPase
c) Vesicular monoamine transporter
d) Proton ATPase
Answer: b) Sodium–potassium ATPase
Which transporter is responsible for transporting serotonin, norepinephrine,
dopamine, and histamine into synaptic vesicles?
a) Vesicular monoamine transporter (VMAT2)
b) Vesicular acetylcholine transporter (VAChT)
c) Vesicular inhibitory amino acid transporter (VIAAT)
d) Vesicular glutamate transporter (VGluT)
Answer: a) Vesicular monoamine transporter (VMAT2)
CHAPTER 2:
Which of the following is true about inverse agonists?
A) They have no activity of their own in the absence of the agonist
B) They can reduce activity below the baseline level when no agonist is present
