UNE Medical Biochemistry Midterm Questions
With Complete Solutions
Which of the following proteins is likely to have quaternary
structure? correct answer: A multimeric protein that contains
multiple peptide chains
Prosthetic groups are complex nonprotein molecules that
participate in catalysis by providing functional groups that form
a covalent intermediate between the enzyme and the substrate.
Which of the following is an example of a coenzyme or cofactor
that participates in a covalent catalysis reaction? correct answer:
Pyridoxal phosphate
Which of the following best describes a protein domain? correct
answer: A section of a protein structure sufficient to perform a
particular chemical or physical task
Cleavage of fructose 1,6 bisphosphate to dihydroxyacetone and
Glyceraldehyde 3-phosphate involves the breaking of a carbon-
carbon bond through a process other than oxidation or
hydrolysis. This is achieved by what class of enzymes? correct
answer: Lyase
A 55-year old man is brought to the emergency room with a
chief complaint of chest pain and tingling in his left arm.
Elevation of which of the following enzymes in circulation
would be most indicative of myocardial infarction? correct
answer: Troponin
, Allosteric activators of hemoglobin will increase substrate
binding through which of the following mechanisms? correct
answer: Binding the protein, and keeping it in the "R"
conformation
Which of the following best describes tertiary structure? correct
answer: Interactions between alpha helices and beta sheets to
form a domain
How do most enzymes reduce the activation energy needed to
move a reaction forward? correct answer: providing an active
site most complementary to the transition state
Domains are common structural elements that retain a particular
function within the protein. Which of the following is an
example of a protein domain? correct answer: An arrangement
of beta-strands connected by alpha-helices (beta-alpha-beta-
alpha)
Which amino acid would not be commonly found in the middle
of an alpha-helical domain? correct answer: Proline
Which of the following is a true statement with regards to the
malate-aspartate shuttle system? correct answer: Generates 2.5
molecules of ATP in mitochondria per each NADH from
glycolysis.
Complex II (Succinate Q-reductase) is not considered part of the
process of oxidative phosphorylation because it is unable to do
With Complete Solutions
Which of the following proteins is likely to have quaternary
structure? correct answer: A multimeric protein that contains
multiple peptide chains
Prosthetic groups are complex nonprotein molecules that
participate in catalysis by providing functional groups that form
a covalent intermediate between the enzyme and the substrate.
Which of the following is an example of a coenzyme or cofactor
that participates in a covalent catalysis reaction? correct answer:
Pyridoxal phosphate
Which of the following best describes a protein domain? correct
answer: A section of a protein structure sufficient to perform a
particular chemical or physical task
Cleavage of fructose 1,6 bisphosphate to dihydroxyacetone and
Glyceraldehyde 3-phosphate involves the breaking of a carbon-
carbon bond through a process other than oxidation or
hydrolysis. This is achieved by what class of enzymes? correct
answer: Lyase
A 55-year old man is brought to the emergency room with a
chief complaint of chest pain and tingling in his left arm.
Elevation of which of the following enzymes in circulation
would be most indicative of myocardial infarction? correct
answer: Troponin
, Allosteric activators of hemoglobin will increase substrate
binding through which of the following mechanisms? correct
answer: Binding the protein, and keeping it in the "R"
conformation
Which of the following best describes tertiary structure? correct
answer: Interactions between alpha helices and beta sheets to
form a domain
How do most enzymes reduce the activation energy needed to
move a reaction forward? correct answer: providing an active
site most complementary to the transition state
Domains are common structural elements that retain a particular
function within the protein. Which of the following is an
example of a protein domain? correct answer: An arrangement
of beta-strands connected by alpha-helices (beta-alpha-beta-
alpha)
Which amino acid would not be commonly found in the middle
of an alpha-helical domain? correct answer: Proline
Which of the following is a true statement with regards to the
malate-aspartate shuttle system? correct answer: Generates 2.5
molecules of ATP in mitochondria per each NADH from
glycolysis.
Complex II (Succinate Q-reductase) is not considered part of the
process of oxidative phosphorylation because it is unable to do
