IMMUNOTHERAPY ADMINISTRATION EXAM LATEST
2024 ACTUAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+
Who can administer chemotherapy? - ANSWER--Registered Nurses with
specialized education, prep and training. See specific state laws and statutes
How often is chemo competency reassessed> - ANSWER--Annual continuing ed
and competency assessment is recommended
What is the dose verification process? - ANSWER---confirm plan with patient
-two practitioners verify: drug name, dose, volume, rate, route, expiration date,
appearance
-document verification in chart
What PPE is required for IV Chemotherapy? - ANSWER---Gloves: two pairs, HD
tested
-Gown: disposable, back closed, long sleeved
-Respirator: NIOSH approved
-Eye & Face: face shield/mask
Neoadjuvant therapy (tumor burden) - ANSWER--Chemo BEFORE primary
treatment (common in breast and colon)
, FUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY ADMINISTRATION EXAM LATEST
2024 ACTUAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+
Adjuvant therapy - ANSWER--Chemo AFTER primary treatment (common in solid
tumor)
Bone Marrow - ANSWER--soft, sponge-like tissue in center of most bones,
produce WBC, RBC, and platelets.
Myelosuppression - ANSWER--bone marrow activity is decreased, causing less
RBC, WBC and Platelets.
Myeloablation - ANSWER--severe myelosuppression
Induction phase - ANSWER--initial phase, typically in hospital, intended
myelosuppression
Consolidation phase (intensification/postremission therapy) - ANSWER--after
successful induction, kills cancer cells left in body (ex radiation, stem cell
transplant)
Synergy - ANSWER--when one chemo drug helps another work better at the same
time
Complete response - ANSWER--no identifiable cancer present for at least one
month or longer
, FUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY ADMINISTRATION EXAM LATEST
2024 ACTUAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+
Partial response - ANSWER--Measurable tumor reduced by 50% for at least one
month with no new tumors
Stable disease - ANSWER--Tumor size reduced by less than 50% or less than 25%
increase in growth
Progressive disease - ANSWER--tumor growth more than 25% or new cancer
What are the phases of the cell cycle? - ANSWER---G1 phase
-S phase
-G2 phase
-M phase
What happens in G1 phase? - ANSWER--The cell increases in size and prepares to
replicate its DNA.
What do chemo drugs do to target S phase? - ANSWER--Prevent cell from making
DNA and/or RNA (replicating)
(ex: antifolates (methotrexate), antipyrimidines (5-fu), antipurines (hydroxyurea))
, FUNDAMENTALS OF CHEMOTHERAPY
IMMUNOTHERAPY ADMINISTRATION EXAM LATEST
2024 ACTUAL EXAM QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+
What do chemo drugs do to target G2 phase? - ANSWER--Cells prepare to divide,
chemo drugs stop development of elements needed for cell division
(ex: topoisomerase I and II inhibitors, bleomycin)
What do chemo drugs do to target M phase? - ANSWER--Cells divide, drugs
prevent cell division, including metaphase arrest or microtubular disorganization
(ex: plant alkaloids and taxanes)
What are some examples of cell cycle non-specific drugs? - ANSWER--Active
throughout the cell cycle:
-alkylating agents
-anthracycline antibiotics
-nitrosureas
-miscellaneous
What are alkylating agents? - ANSWER---cell cycle nonspecific
-damage DNA to prevent cancer cells from reproducing
-create breaks in DNA
Cyclophosphamide? - ANSWER---alkylating agent
-treats: leukemia, lymphoma, breast/ovarian CA, myeloma, neuroblastoma,
mycosis fungoides, retinoblastoma.