Heme Immunotherapy and antineoplastics Exam with complete solution

What are two situations in which it would be advantageous to temporarily suppress inflammatory responses? - AnswerTransplantation, treatment of autoimmune disease What are two situations in which it would be advantageous to enhance immune responses? - AnswerPrevention/treatment of infectious diseases and cancer what type of immunization is Vaccination considered (active vs passive)? What type of response is elicited preferably? - AnswerActive immunization Humoral response (antibody production from B/plasma cells)- this is preferably to cell-mediated immunity what two bacteria are targeted in Caries Vaccines? How do they prevent the bacterial disease process? Is there a commercially available vaccine for caries? - AnswerStreptococcus mutans and Streptococcus subrinus prevent adherence of bacteria via generation of secretory IgA antibodies and targeting isolated antigens needed by bacteria in plaque formation there is no commercially active vaccine available what are two given categories of immunostimulants? How do they work? - Answer1. Thymic extracts such as Thymosin and Thymostimulin -induce T-cell maturation -especially effective in patients with absence of thymus (DiGeorge Syndrome) 2. Levamisole (ergamisol) -antihelminthic agent -thymomimetic effects; affects multiple cell populations as well (PMNs, MQs, etc.) -show to be effective for recurrent aphthous ulcers and herpes labialis