Central-Nervous-System-Stimulants-And-Related-Drugs.pptx

Central Nervous System
Stimulants and Related Drugs




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, CNS Stimulants

 Drugs that stimulate a specific area of the brain
or spinal cord
 Neurons contain receptors for excitatory
neurotransmitters, including dopamine
(dopaminergic drugs), norepinephrine
(adrenergic drugs), and serotonin (serotonergic
drugs)
 Sympathomimetic drugs

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, Classification

 Classified according to
 Chemical structural similarities: amphetamines,
serotonin agonists, sympathomimetics, and
xanthines
 Site of therapeutic action in the central nervous
system (CNS)
 Major therapeutic uses: anti–attention deficit
disorder, antinarcoleptic, anorexiant, antimigraine,
and analeptic drugs

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, Attention Deficit
Hyperactivity Disorder (ADHD)
 Most common psychiatric disorder in children,
affecting 4% to 10% of school-age children
 Boys are affected from two to nine times more
often than girls.
 Primary symptoms of ADHD are inappropriate
ability to maintain attention span or the
presence of hyperactivity and impulsivity.
 Drug therapy for both childhood and adult ADHD
is the same.
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