CHEM 441A FINAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS.

CHEM 441A FINAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS. Instructions: 1. DO NOT begin the exam until instructed to do so. 2. SWITCH OFF your phones. 3. Make sure there is a total of 12 pages. 4. Write your Name AND Exam number (A or B) on your Scantron. 5. When finished, place Exam sheet and Scantron and return all materials to the instructor. Summary of points: 1. Answer on Scantron Section A (Q# 1….60) (60 Points) 2. Answer on the Exam Sheet Section B, C, and D (Q# 61-90) (40 Points) 3. Answer on the Exam Sheet Section E (Q# 91-93) (6 Points) 4. TOTAL 100 + 6 points A B ______ C______ 4 TOTAL 2 SECTION A – Please, answer these questions on Scantron (1x60 = 60 points). 1. In the figure below, where is a hydrogen bond acceptor located? a) B b) C c) D d) A 2. For ATP (shown below), cleavage of the bond between __________ has the largest ΔG°′. a) adenine and ribose b) β phosphate and γ phosphate c) α phosphate and β phosphate d) ribose and α phosphate 3. All of the following are important for enzyme-substrate interactions EXCEPT a) hydrogen bonds. b) van der Waals interactions c) ionic interactions. d) covalent bonds. 4. When a protein folds in an aqueous solution, which of the following is correct? a) A mixture of polar and non-polar amino acids is found in the interior of the protein. b) Polar amino acids are found in the interior of the protein c) Water is always excluded from the active site in the interior of the protein. d) Non-polar amino acids are found in the interior of the protein. 5. Which of the following is correct about biological membranes? a) Phospholipid tails are directed toward the aqueous environment b) Biological membranes are made up of a lipid monolayer. c) Phospholipid head groups are directed toward the aqueous environment. d) Molecules freely pass through the membrane. 6. Which situation described below would result in the MOST rigid biological membrane? a) A high ratio of cholesterol b) A large number of bulky, glycosylated head groups c) A high ratio of unsaturated fatty acid tails in the phospholipids d) A small amount of cholesterol 7. Which of the following three-letter amino acid sequence match with this single-letter sequence FYAKGPE? a) Phe-Tyr-Asp-Lys-Gln-Phe-Glu b) Phe-Tyr-Asn-Lys-Gly-Pro-Glu c) Phe-Tyr-Ala-Lys-Gly-Pro-Glu d) Phe-Tyr-Ala-Lys-Glu-Phe-Gln 3 8. Transformation is a transfer of DNA a) Mediated through viral infection b) Mediated through bacterial mating c) Mediated through uptake of exogenous DNA from the medium d) All the above 9. Which of the following nucleotides are used in Sanger method of DNA sequencing? a) Deoxyribonucleotides b) Ribonucleotides c) Dideoxyribonucleotides d) Diribonucleotides 10. Which of the following is the correct order for DNA condensation in eukaryotes? a) Nucleosomes, chromatin, loops, condensed coils, chromosome b) Chromatin, nucleosomes, loops, condensed coils, chromosome c) Nucleosomes, condensed coils, loops, chromatin, chromosome d) Chromatin, nucleosomes, condensed coils, loops, chromosome 11. The figure below shows a nucleosome core particle. Which of the following is INCORRECT? a) H1 histone protein is not part of the histone protein core. b) The histone protein core consists of eight histone proteins. c) DNA wraps around the histone protein core twice. d) The interactions between the DNA and the histone protein core are sequence specific. 12. Which of the following is considered gene-rich chromatin? a) Euchromatin c) Heterochromatin b) Centromeres d) Telomeres .